Zobrazeno 1 - 10
of 557
pro vyhledávání: '"Ch, Evans"'
Autor:
RE Sherwin, EB McGlinch, MA Barry, CM Lopez De Padilla, DR Montonye, CH Evans, A Atasoy-Zeybek
Publikováno v:
European Cells & Materials, Vol 46, Pp 154-170 (2023)
Tendon injuries present a considerable clinical challenge due to the limited regenerative capacity of tendons. The use of gene transfer to deliver growth factors to sites of tendon damage has been suggested as a promising strategy for improving tendo
Externí odkaz:
https://doaj.org/article/1c335fb313b241aa9680ba862c6f47c9
Autor:
CJ Peniche Silva, SA Müller, N Quirk, RE De la Vega, MJ Coenen, CH Evans, ER Balmayor, M van Griensven
Publikováno v:
European Cells & Materials, Vol 44, Pp 43-55 (2022)
The interphase between tendon and bone consists of a highly specialised tissue called enthesis. Typically, the enthesis is described as a succession of four different zones: tendon, non-mineralised fibrocartilage, mineralised fibrocartilage and bone.
Externí odkaz:
https://doaj.org/article/2da97e09d94d4b1fad71d50c4618a74a
Autor:
CV Nagelli, A Hooke, N Quirk, CL De Padilla, TE Hewett, M van Griensven, M Coenen, L Berglund, CH Evans, SA Müller
Publikováno v:
European Cells & Materials, Vol 43, Pp 153-161 (2022)
The Achilles tendon is the strongest tendon in the human body but its mechanical behaviour during failure has been little studied and the basis of its high tensile strength has not been elucidated in detail. In the present study, healthy, human, Achi
Externí odkaz:
https://doaj.org/article/c02cec0f7dbc456bbfe9d2af8b6eb653
Publikováno v:
European Cells & Materials, Vol 41, Pp 668-679 (2021)
The present review acknowledges the tremendous impact of Stephan Perren’s strain theory, considered with respect to the earlier contributions of Roux and Pauwels. Then, it provides further insight by examining how the concept of reverse dynamisatio
Externí odkaz:
https://doaj.org/article/6eff5c44e8584847a7b6b885adbc4672
Autor:
T-Y Liu, M Bartnikowski, AC Wu, M Veitch, KA Sokolowski, SM Millard, AR Pettit, V Glatt, CH Evans, JW Wells
Publikováno v:
European Cells & Materials, Vol 41, Pp 345-354 (2021)
Clinical management of delayed healing or non-union of long bone fractures and segmental defects poses a substantial orthopaedic challenge. There are suggestions in the literature that bone healing may be enhanced by inhibiting the activities of T an
Externí odkaz:
https://doaj.org/article/350f73564bb14ea8b5484ab025e30d00
Publikováno v:
European Cells & Materials, Vol 40, Pp 160-171 (2020)
There is much interest in understanding the influence of the immune system on bone healing, including a number of reports suggesting a beneficial effect of FK506 (tacrolimus) in this regard. The influence of FK506 in a rat, femoral, critical size def
Externí odkaz:
https://doaj.org/article/b0f649660b554ceba5f07e254fc65794
Publikováno v:
European Cells & Materials, Vol 38, Pp 14-22 (2019)
Bone autografting remains the clinical model of choice for resolving problematic fractures. The precise mechanisms through which the autograft promotes bone healing are unknown. The present study examined the hypothesis that cells within the autograf
Externí odkaz:
https://doaj.org/article/24e495b740214da08456cb6bd2741adb
Publikováno v:
European Cells & Materials, Vol 35, Pp 318-334 (2018)
Several growth factors (GFs) are expressed as tendons heal, but it remains unknown whether their combined application enhances the healing process. This matter was addressed by applying a combination of basic fibroblast growth factor (bFGF), bone mor
Externí odkaz:
https://doaj.org/article/c5adf0715db94ee6868a5b9967854b25
Autor:
F Liu, E Ferreira, RM Porter, V Glatt, M Schinhan, Z Shen, MA Randolph, CA Kirker-Head, C Wehling, MS Vrahas, CH Evans, JW Wells
Publikováno v:
European Cells & Materials, Vol 30, Pp 118-131 (2015)
Large segmental defects in bone fail to heal and remain a clinical problem. Muscle is highly osteogenic, and preliminary data suggest that autologous muscle tissue expressing bone morphogenetic protein-2 (BMP-2) efficiently heals critical size defect
Externí odkaz:
https://doaj.org/article/3ef358fe86804d52828a878a4dea2ba2
Publikováno v:
European Cells & Materials, Vol 23, Pp 289-299 (2012)
Very little is known about the influence of the mechanical environment on the healing of large segmental defects. This partly reflects the lack of standardised, well characterised technologies to enable such studies. Here we report the design, constr
Externí odkaz:
https://doaj.org/article/3be9ffce621b44268b999a71b4454dbc