Zobrazeno 1 - 10
of 294
pro vyhledávání: '"Cg, Begley"'
Autor:
T Haimowitz, Arnone, SK Chunduru, GS Kapoor, Y Mitsuuchi, CG Begley, SC Beck, ME Seipel, Y Deng, SM Condon, CA Benetatos, MA McKinlay
Publikováno v:
Cell Death Discovery
The inhibitor of apoptosis (IAP) proteins have pivotal roles in cell proliferation and differentiation, and antagonizing IAPs in certain cancer cell lines results in induction of cell death. A variety of IAP antagonist compounds targeting the baculov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b760e7bc7de64e5935eefe0ef26fbd95
http://europepmc.org/articles/PMC5238498
http://europepmc.org/articles/PMC5238498
Autor:
BA Miller, J Floros, JY Cheung, DM Wojchowski, L Bell, CG Begley, NJ Elwood, J Kreider, C Christian
Publikováno v:
Blood. 84:2971-2976
Steel factor is one of the growth factors that controls the proliferation and differentiation of hematopoietic cells and SCL, also known as Tcl-5 or Tal-1, is a transcription factor involved in erythropoiesis. In this report, we studied the role of S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf30018fcead08ec95ba2e575c798bb4
https://doi.org/10.1182/blood.v84.9.2971.bloodjournal8492971
https://doi.org/10.1182/blood.v84.9.2971.bloodjournal8492971
Distinct changes in pulmonary surfactant homeostasis in common beta-chain- and GM-CSF-deficient mice
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 278(6)
Pulmonary alveolar proteinosis (PAP) is caused by inactivation of either granulocyte-macrophage colony-stimulating factor (GM-CSF) or GM receptor common β-chain (βc) genes in mice [GM(−/−), βc(−/−)], demonstrating a critical role of GM-CSF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0f5e3ee61830d21f94a4fc421c8cfba
https://pubmed.ncbi.nlm.nih.gov/10835321
https://pubmed.ncbi.nlm.nih.gov/10835321
Autor:
Jf, Seymour, Cg, Begley, Dirksen U, Jeffrey Presneill, Na, Nicola, Pe, Moore, Od, Schoch, van Asperen P, Roth B, Burdach S, Ar, Dunn
Publikováno v:
Europe PubMed Central
The pathogenesis of acquired pulmonary alveolar proteinosis (PAP), a rare lung disease characterized by excessive surfactant accumulation within the alveolar space, remains obscure. Gene-targeted mice lacking the hematopoietic growth factor granulocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ba085e55a9b304b428f538d848427378
https://pubmed.ncbi.nlm.nih.gov/9763547
https://pubmed.ncbi.nlm.nih.gov/9763547
Publikováno v:
Europe PubMed Central
The SCL/TAL-1 gene encodes a basic helix-loop-helix transcription factor that is expressed in multipotent hematopoietic progenitors before lineage commitment. Its expression is maintained during differentiation along erythroid, mast, and megakaryocyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e2d5ac2d45f8b686df2f0bb14a2b6824
https://pubmed.ncbi.nlm.nih.gov/7632958
https://pubmed.ncbi.nlm.nih.gov/7632958
Publikováno v:
Europe PubMed Central
The SCL gene encodes a member of the helix-loop-helix (HLH) family of transcription factors and is reportedly involved in up to 25% of T-cell acute lymphoblastic leukemia (T-ALL). We have surveyed over 120 primary human tumors including melanomas, my
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::89aa06359e20e98e4894918d95dff977
https://pubmed.ncbi.nlm.nih.gov/1625484
https://pubmed.ncbi.nlm.nih.gov/1625484
Publikováno v:
Europe PubMed Central
The alpha-chain of the interleukin 2 receptor (IL-2R alpha) is expressed on monocytes and macrophages after activation by bacterial lipopolysaccharide (LPS) and interferon-gamma (IFN-gamma). In the present study, we investigated whether the expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8a0bd17b0586020c9e8046ef98fe4af3
https://pubmed.ncbi.nlm.nih.gov/1587308
https://pubmed.ncbi.nlm.nih.gov/1587308
Autor:
D Metcalf, CG Begley, GR Johnson, NA Nicola, MA Vadas, AF Lopez, DJ Williamson, GG Wong, SC Clark, EA Wang
Publikováno v:
Blood. 67:37-45
Recombinant human granulocyte-macrophage colony-stimulating factor (rH GM-CSF) was purified to homogeneity from medium conditioned by COS cells transfected with a cloned human GM-CSF cDNA and shown to be an effective proliferative stimulus in human m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71a4125679bd547a45a41db9de45cb43
https://doi.org/10.1182/blood.v67.1.37.bloodjournal67137
https://doi.org/10.1182/blood.v67.1.37.bloodjournal67137
Autor:
Aw, Burgess, Cg, Begley, Gr, Johnson, Af, Lopez, Dj, Williamson, Jj, Mermod, Richard Simpson, Schmitz A, Jf, Delamarter
Publikováno v:
Europe PubMed Central
Human granulocyte-macrophage colony stimulating factor (GM-CSF) has been synthesized in high yield using a temperature inducible plasmid in Escherichia coli. The human GM-CSF is readily isolated from the bacterial proteins because of its differential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2bb85515208d4296d526b526f28a5c3
https://doi.org/10.1182/blood.v69.1.43.bloodjournal69143
https://doi.org/10.1182/blood.v69.1.43.bloodjournal69143
Publikováno v:
Blood. 68(1)
The survival of purified human blood neutrophils and eosinophils was monitored using microwell cultures. Survival was enhanced in cultures containing human or murine colony-stimulating factors (CSFs). The survival of both cell types was enhanced by p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab8296a3935f80c6f60b6672cb329733
https://pubmed.ncbi.nlm.nih.gov/3487354
https://pubmed.ncbi.nlm.nih.gov/3487354