Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Cezar Gavrilovici"'
Autor:
Devansh Agarwal, Nicholas Dash, Kevin W. Mazo, Manan Chopra, Maria P. Avila, Amit Patel, Ryan M. Wong, Cairang Jia, Hope Do, Jie Cheng, Colette Chiang, Shawna L. Jurlina, Mona Roshan, Michael W. Perry, Jong M. Rho, Risa Broyer, Cassidy D. Lee, Robert N. Weinreb, Cezar Gavrilovici, Nicholas W. Oesch, Derek S. Welsbie, Karl J. Wahlin
Publikováno v:
npj Regenerative Medicine, Vol 8, Iss 1, Pp 1-18 (2023)
Abstract In optic neuropathies, including glaucoma, retinal ganglion cells (RGCs) die. Cell transplantation and endogenous regeneration offer strategies for retinal repair, however, developmental programs required for this to succeed are incompletely
Externí odkaz:
https://doaj.org/article/382428f7635b42d8a434f9b8270d4a90
Publikováno v:
Neurobiology of Disease, Vol 48, Iss 3, Pp 317-328 (2012)
Interneuronal functional diversity is thought to be an important factor in the control of neural network oscillations in many brain regions. Specifically, interneuron action potential firing patterns are thought to modulate brain rhythms. In neurolog
Externí odkaz:
https://doaj.org/article/17ef931414dc45dcb7767ced120467c5
Autor:
Deepika Dogra, Paola L. Meza‐Santoscoy, Cezar Gavrilovici, Renata Rehak, Cristiane L. R. de la Hoz, Kingsley Ibhazehiebo, Jong M. Rho, Deborah M. Kurrasch
Publikováno v:
Epilepsia.
Autor:
Deepika Dogra, Paola L. Meza-Santoscoy, Renata Rehak, Cristiane L R de la Hoz, Cezar Gavrilovici, Kingsley Ibhazehiebo, Jong M. Rho, Deborah M. Kurrasch
ObjectiveKCNA1 mutations are associated with a rare neurological movement disorder known as episodic ataxia type 1 (EA1), with epilepsy as a common comorbidity. Current medications only provide partial relief to ataxia and/or seizures, making new dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08caf1feec59d20c6af6075a84331b0e
https://doi.org/10.1101/2022.09.28.509973
https://doi.org/10.1101/2022.09.28.509973
Autor:
Yulan Jiang, Minh Dang Nguyen, Jong M. Rho, Milène Vandal, Fan Gao, G. Campbell Teskey, Sukyoung Lee, Sang Ki Park, Morris H. Scantlebury, Cezar Gavrilovici, Li-Huei Tsai, Ivana Kiroski
Publikováno v:
Cereb Cortex
Cerebral cortex (New York, N.Y. : 1991), vol 30, iss 9
Cerebral cortex (New York, N.Y. : 1991), vol 30, iss 9
The glycoprotein Reelin maintains neuronal positioning and regulates neuronal plasticity in the adult brain. Reelin deficiency has been associated with neurological diseases. We recently showed that Reelin is depleted in mice with a targeted disrupti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf5af9f13aa514061182f5abea1d2a1b
https://resolver.caltech.edu/CaltechAUTHORS:20200522-124105657
https://resolver.caltech.edu/CaltechAUTHORS:20200522-124105657
Autor:
Cezar Gavrilovici, Jong M. Rho
Publikováno v:
Journal of inherited metabolic disease, vol 44, iss 1
Metabolic epilepsies arise in the context of rare inborn errors of metabolism (IEM), notably glucose transporter type 1 deficiency syndrome, succinic semialdehyde dehydrogenase deficiency, pyruvate dehydrogenase complex deficiency, nonketotic hypergl
Autor:
Yulan Jiang, Ivana Kiroski, Jong M. Rho, Minh Dang Nguyen, Cezar Gavrilovici, G. Campbell Teskey
Publikováno v:
Cerebral Cortex Communications
Mutations in cytoskeletal proteins can cause early infantile and childhood epilepsies by misplacing newly born neurons and altering neuronal connectivity. In the adult epileptic brain, cytoskeletal disruption is often viewed as being secondary to abe
Autor:
Deborah M. Kurrasch, Renata Rehak, Do Young Kim, Gaurav Kaushik, Jong M. Rho, Nandan Nath, Shun-Chieh Ma, Paola L Meza Santoscoy, Cristiane L. de la Hoz, Lucas Scott, Kingsley Ibhazehiebo, Cezar Gavrilovici
Publikováno v:
Brain
Brain : a journal of neurology, vol 141, iss 3
Brain : a journal of neurology, vol 141, iss 3
Drug discovery in epilepsy has historically been biased towards transmembrane channels and receptors. Ibhazehiebo et al. describe a novel, metabolism-based drug discovery platform that assays for bioenergetic changes in zebrafish models, and demonstr
Autor:
Muhammad Iqbal Choudhary, Cezar Gavrilovici, Michael O. Poulter, Atta-ur Rahman, Shabana Usman Simjee, Syed Uzair Ali Shah, Margaret Fahnestock, Muhammad Nadeem Ashraf, Farzana Shaheen
Publikováno v:
Journal of Neurochemistry. 126:651-661
Here, we explore the mechanism of action of isoxylitone (ISOX), a molecule discovered in the plant Delphinium denudatum, which has been shown to have anticonvulsant properties. Patch-clamp electrophysiology assayed the activity of ISOX on voltage-gat