Výsledky vyhledávání - "Ceylan Verda Bitirim"

Akademický článek

Cardioprotective effect of extracellular vesicles derived from ticagrelor-pretreated cardiomyocyte on hyperglycemic cardiomyocytes through alleviation of oxidative and endoplasmic reticulum stress

Autor: Ceylan Verda Bitirim, Zeynep Busra Ozer, Dunya Aydos, Kardelen Genc, Seyma Demirsoy, Kamil Can Akcali, Belma Turan

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)

Abstract Extracellular vesicles (EVs) play important roles in diabetes mellitus (DM) via connecting the immune cell response to tissue injury, besides stimulation to muscle insulin resistance, while DM is associated with increased risks for major car

Externí odkaz: https://doaj.org/article/ebdb4b158ff145298057a413b4b344fc

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Insulin acts as an atypical KCNQ1/KCNE1‐current activator and reverses long QT in insulin‐resistant aged rats by accelerating the ventricular action potential repolarization through affecting the β 3 ‐adrenergic receptor signaling pathway

Autor: Erkan Tuncay, Yusuf Olgar, Aysegul Durak, Belma Turan, Ceylan Verda Bitirim

Publikováno v: Journal of Cellular Physiology. 237:1353-1371

Insufficient-heart function is associated with myocardial insulin resistance in the elderly, particularly associated with long-QT, in a dependency on dysfunctional KCNQ1/KCNE1-channels. So, we aimed to examine the contribution of alterations in KCNQ1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5dc9e2dfdf904e460af733401ccdcf83
https://doi.org/10.1002/jcp.30597

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Hemin shows antiviral activity in vitro, possibly through suppression of viral entry mediators

Autor: Mehmet Altay Unal, Ceylan Verda Bitirim, Julia Somers, Gokce Yagmur Summak, Omur Besbinar, Ebru Kocakaya, Cansu Gurcan, Hasan Nazir, Zeynep Busra Aksoy Ozer, Sibel Aysil Ozkan, Sidar Bereketoglu, Aykut Ozkul, Emek Demir, Kamil Can Akcali, Acelya Yilmazer

Heme oxygenase-1 (HO-1) is a stress-induced enzyme that catalyzes the breakdown of heme into biliverdin, carbon monoxide, and iron. Targeting HO-1 to treat severe COVID-19 has been suggested by several groups, yet the role of HO-1 in SARS-CoV-2 infec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6a5dcef7373beafea6fa999a4ee7d41d
https://doi.org/10.1101/2022.05.24.493187

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Utility investigation of automated techniques in hematopoietic progenitor cell count and viability assessment in the Good Manufacturing Practice (GMP) setting

Autor: Şükran Şeker, Klara Dalva, Orkun Cevheroğlu, Oznur Coskun, Aydin Ozturk, Pelin Kilic, Ayşe Eser Elçin, Ozge Lalegul Ulker, Pinar Baydin, Açelya Yilmazer, Mahmut Parmaksiz, Senay Ipek, Gunseli Cubukcuoglu Deniz, Meltem Bay, Gunhan Gurman, Ceylan Verda Bitirim

Publikováno v: EXPERIMENTAL BIOMEDICAL RESEARCH; Vol 3 No 4 (2020): Experimental Biomedical Research; 231-238

Aim: To compare our parameters as regards: i) cell count via two different automated cell count techniques, and ii) viability via automated trypan blue exclusion and 7-aminoactinomycin D (7-AAD) staining. Method: We used the trypan blue exclusion tec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31875b30e2ac031a07fd35db8bbbb4ef
https://doi.org/10.30714/j-ebr.2020463606

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Titin and CK2α are New Intracellular Targets in Acute Insulin Application-Associated Benefits on Electrophysiological Parameters of Left Ventricular Cardiomyocytes From Insulin-Resistant Metabolic Syndrome Rats

Autor: Aysegul Durak, Belma Turan, Ceylan Verda Bitirim

Publikováno v: Cardiovascular Drugs and Therapy. 34:487-501

Previous studies have demonstrated that a high-carbohydrate intake could induce metabolic syndrome (MetS) in male rats with marked cardiac functional abnormalities. In addition, studies mentioned some benefits of insulin application on these complica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f13026d5cd61c6862d0367b44241a46
https://doi.org/10.1007/s10557-020-06974-2

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