Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity.

Autor: Hamid MHBA; CAMS Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Cespedes PF; CAMS Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK., Jin C; CAMS Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Department of Cardiothoracic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China., Chen JL; CAMS Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; MRC Translational Immune Discovery Unity, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Gileadi U; MRC Translational Immune Discovery Unity, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Antoun E; CAMS Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Liang Z; CAMS Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Target Discovery Institute, Centre for Medicines Discovery, University of Oxford, Oxford, UK., Gao F; CAMS Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Teague R; CAMS Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK., Manoharan N; CAMS Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Maldonado-Perez D; CAMS Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK., Khalid-Alham N; Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Oxford, UK.; Oxford National Institute of Health Research (NIHR) Biomedical Research Centre, John Radcliffe Hospital, Oxford, UK., Cerundolo L; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK., Ciaoca R; CAMS Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Hester SS; Target Discovery Institute, Centre for Medicines Discovery, University of Oxford, Oxford, UK., Pinto-Fernández A; CAMS Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Target Discovery Institute, Centre for Medicines Discovery, University of Oxford, Oxford, UK., Draganov SD; CAMS Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Target Discovery Institute, Centre for Medicines Discovery, University of Oxford, Oxford, UK., Vendrell I; CAMS Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Target Discovery Institute, Centre for Medicines Discovery, University of Oxford, Oxford, UK., Liu G; CAMS Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Yao X; CAMS Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Kvalvaag A; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.; Department of Molecular Cell Biology, Institute of Cancer Research, Oslo University Hospital, Oslo, Norway., Dominey-Foy DCC; CAMS Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Nanayakkara C; CAMS Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Kanellakis N; CAMS Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Oxford National Institute of Health Research (NIHR) Biomedical Research Centre, John Radcliffe Hospital, Oxford, UK.; Laboratory of Pleural and Lung Cancer Translational Research, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Oxford Centre for Respiratory Medicine, Churchill Hospital, Oxford University Hospitals, Oxford, UK., Chen YL; CAMS Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; MRC Translational Immune Discovery Unity, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Waugh C; Flow Cytometry Facility, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Clark SA; Flow Cytometry Facility, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Clark K; Flow Cytometry Facility, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Sopp P; Flow Cytometry Facility, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Rahman NM; CAMS Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Oxford National Institute of Health Research (NIHR) Biomedical Research Centre, John Radcliffe Hospital, Oxford, UK.; Laboratory of Pleural and Lung Cancer Translational Research, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Oxford Centre for Respiratory Medicine, Churchill Hospital, Oxford University Hospitals, Oxford, UK., Verrill C; CAMS Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.; Oxford National Institute of Health Research (NIHR) Biomedical Research Centre, John Radcliffe Hospital, Oxford, UK., Kessler BM; CAMS Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Target Discovery Institute, Centre for Medicines Discovery, University of Oxford, Oxford, UK., Ogg G; CAMS Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; MRC Translational Immune Discovery Unity, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Fernandes RA; CAMS Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Fisher R; CAMS Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Target Discovery Institute, Centre for Medicines Discovery, University of Oxford, Oxford, UK., Peng Y; CAMS Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; MRC Translational Immune Discovery Unity, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Dustin ML; CAMS Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK., Dong T; CAMS Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK. tao.dong@ndm.ox.ac.uk.; MRC Translational Immune Discovery Unity, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK. tao.dong@ndm.ox.ac.uk.

Publikováno v: Nature immunology [Nat Immunol] 2024 May; Vol. 25 (5), pp. 834-846. Date of Electronic Publication: 2024 Apr 01.

Focusing on CD8⁺ T-cell phenotypes: improving solid tumor therapy.

Autor: Yao, Zhouchi¹ (AUTHOR), Zeng, Yayun² (AUTHOR), Liu, Cheng¹ (AUTHOR), Jin, Huimin² (AUTHOR), Wang, Hong³ (AUTHOR), Zhang, Yue² (AUTHOR) 2021000048@usc.edu.cn, Ding, Chengming¹ (AUTHOR) 2018011096@usc.edu.cn, Chen, Guodong¹ (AUTHOR) chenguodong@usc.edu.cn, Wu, Daichao^1,2 (AUTHOR) wudaichao@usc.edu.cn

Publikováno v: Journal of Experimental & Clinical Cancer Research (17569966). 9/28/2024, Vol. 43 Issue 1, p1-30. 30p.

Chemotherapy-elicited extracellular vesicle CXCL1 from dying cells promotes triple-negative breast cancer metastasis by activating TAM/PD-L1 signaling.

Autor: Wang, Shengqi^1,2,3,4 (AUTHOR), Li, Jing² (AUTHOR), Hong, Shicui² (AUTHOR), Wang, Neng^2,4,5 (AUTHOR), Xu, Shang² (AUTHOR), Yang, Bowen^1,2 (AUTHOR), Zheng, Yifeng^1,2,4 (AUTHOR), Zhang, Juping^1,2,4 (AUTHOR), Pan, Bo^1,2 (AUTHOR), Hu, Yudie^1,2 (AUTHOR), Wang, Zhiyu^1,2,3,4,5 (AUTHOR) wangzhiyu@gzucm.edu.cn

Publikováno v: Journal of Experimental & Clinical Cancer Research (17569966). 4/23/2024, Vol. 43 Issue 1, p1-23. 23p.

Distinct roles for type I and type III interferons in virulent human metapneumovirus pathogenesis.

Autor: Zhang, Yu¹ (AUTHOR), Xu, Jiuyang^1,2 (AUTHOR), Miranda-Katz, Margot¹ (AUTHOR), Sojati, Jorna¹ (AUTHOR), Tollefson, Sharon J.³ (AUTHOR), Manni, Michelle L.¹ (AUTHOR), Alcorn, John F.¹ (AUTHOR), Sarkar, Saumendra N.⁴ (AUTHOR), Williams, John V.^1,4,5 (AUTHOR) jvw@pitt.edu

Publikováno v: PLoS Pathogens. 2/5/2024, Vol. 20 Issue 2, p1-25. 25p.

Is the tumor cell side of the immunological synapse a polarized secretory domain?

Autor: Biolato, Andrea Michela, Filali, Liza, Fernandes, Diogo Pereira, Moreau, Flora, Mgrditchian, Takouhie, Hoffmann, Céline, Thomas, Clément

Publikováno v: Frontiers in Immunology; 2024, p1-9, 9p