Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Ceslava Kairane"'
Publikováno v:
Journal of Chemistry, Vol 2019 (2019)
A glutathione (L-γ-glutamyl-L-cysteinylglycine, GSH) analogue, UPF1 (O-methyl-L-tyrosinylglutathione), has been shown to increase intracellular concentration of total glutahione (tGSH) in K562 cells. The synthesis of GSH is a two-step process that r
Externí odkaz:
https://doaj.org/article/744d07f6ceee4f41a41262600e45a878
Publikováno v:
Journal of Chemistry, Vol 2019 (2019)
A glutathione (L-γ-glutamyl-L-cysteinylglycine, GSH) analogue, UPF1 (O-methyl-L-tyrosinylglutathione), has been shown to increase intracellular concentration of total glutahione (tGSH) in K562 cells. The synthesis of GSH is a two-step process that r
Publikováno v:
Proceedings of the 35th European Peptide Symposium.
Autor:
Kersti Zilmer, Tiina Ristimäe, Piibe Muda, Ceslava Kairane, Mihkel Zilmer, Rein Teesalu, Krista Fischer, Priit Kampus
Publikováno v:
Journal of Hypertension. 23:105-112
To compare the effect of candesartan or amlodipine on concentrations of cellular markers of oxidative stress, plasma homocysteine and vitamins in hypertensive patients.Forty-nine middle-aged patients with untreated stage I-II essential hypertension w
Autor:
Kersti Zilmer, Toomas Karu, Mihkel Zilmer, Jane Lehtmaa, Ceslava Kairane, Anatoli Landõr, Tiiu Vihalemm, Jelena Vider, Tiiu Kullisaar
Publikováno v:
Pathophysiology. 7:263-270
The relationship between exhaustive exercise, oxidative stress, the protective capacity of the antioxidant defense system and cellular immune response has been determined. Exhaustive exercise in well-trained young men (n=19)-induced leukocytosis, dec
Publikováno v:
International Journal of Peptides
The main goal of the present paper was to examine the influence of the replacement ofγ-Glu moiety toα-Glu in glutathione and in its antioxidative tetrapeptidic analogue UPF1 (Tyr(Me)-γ-Glu-Cys-Gly), resulting inα-GSH and UPF17 (Tyr(Me)-Glu-Cys-Gl
Autor:
Riina Mahlapuu, Ceslava Kairane, Mihkel Zilmer, Kersti Ehrlich, Ingrid Oit, Katrin Ida, Ursel Soomets
Publikováno v:
Free radical research. 43(6)
Previously the authors have designed and synthesized a library of antioxidative glutathione analogues called UPF peptides which are superior to glutathione in hydroxyl radical elimination. This paper is a follow-up study which investigated the effect
Publikováno v:
Clinica chimica acta; international journal of clinical chemistry. 359(1-2)
Background To investigate whether cardioplegia-related myocardial necrosis, lactate and glutathione release are predictive for early postoperative cardiac function after coronary artery bypass grafting (CABG). Methods Twelve patients with stabile ang
Autor:
Krista Fischer, Kersti Zilmer, Tiina Ristimäe, Ceslava Kairane, Piibe Muda, Priit Kampus, Mihkel Zilmer, Rein Teesalu
Publikováno v:
Journal of hypertension. 21(12)
OBJECTIVE Intracellular glutathione in its reduced state is a principal cellular biomolecule with antioxidant activity. Glutathione and homocysteine metabolism are closely associated. As both oxidative stress and hyperhomocystinemia are associated wi
Autor:
Kersti Zilmer, Sirje Kaur, Maigi Eisen, Tiiu Vihalemm, Ceslava Kairane, Tiiu Kullisaar, Aune Rehema, Mihkel Zilmer
Publikováno v:
Biomedicinepharmacotherapy = Biomedecinepharmacotherapie. 58(4)
We investigated whether the oxidative stress (OS) caused by skin inflammation could reflect in the blood, in a 21-year-old female student sensitized to nickel, colophony and abitole with often relapsing allergic contact dermatitis (ACD). As glutathio