Zobrazeno 1 - 10
of 260
pro vyhledávání: '"Ceshi Chen"'
Autor:
Wei Li, Chuanyu Yang, Zhuo Cheng, Yuanyuan Wu, Sihan Zhou, Xiaowei Qi, Yi Zhang, Jinhui Hu, Mingjin Xie, Ceshi Chen
Publikováno v:
MedComm, Vol 5, Iss 8, Pp n/a-n/a (2024)
Abstract Colorectal cancer (CRC) is one of the most common malignancies worldwide. In the clinical realm, platinum‐based drugs hold an important role in the chemotherapy of CRC. Nonetheless, a multitude of patients, due to tumor protein 53 (TP53) g
Externí odkaz:
https://doaj.org/article/b58a674ecc524aa083d0d3a7f9c21779
Autor:
Qiaodan Deng, Jiankun Qiang, Cuicui Liu, Jiajun Ding, Juchuanli Tu, Xueyan He, Jie Xia, Xilei Peng, Siqin Li, Xian Chen, Wei Ma, Lu Zhang, Yi‐Zhou Jiang, Zhi‐Ming Shao, Ceshi Chen, Suling Liu, Jiahui Xu, Lixing Zhang
Publikováno v:
Advanced Science, Vol 11, Iss 29, Pp n/a-n/a (2024)
Abstract Breast tumor‐initiating cells (BTICs) of triple‐negative breast cancer (TNBC) tissues actively repair DNA and are resistant to treatments including chemotherapy, radiotherapy, and targeted therapy. Herein, it is found that a previously r
Externí odkaz:
https://doaj.org/article/1e3b009041f14a21a1f006ddc2dac957
Autor:
Wenmin Chen, Yue Wu, Chuanyu Yang, Wenlong Ren, Lei Hou, Huichun Liang, Tingyue Wu, Yanjie Kong, Jiao Wu, Yu Rao, Ceshi Chen
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 116972- (2024)
Breast cancer is one of the most prevalent malignancies affecting women worldwide, underscoring the urgent need for more effective and specific treatments. Proteolysis-targeting chimeras (PROTACs) have emerged as a promising strategy to develop new l
Externí odkaz:
https://doaj.org/article/6b83428d32704c5497033a2f9e81117e
Autor:
Fei Luo, Mingda Zhang, Bowen Sun, Chenxin Xu, Yi Yang, Yingwen Zhang, Shanshan Li, Guoyu Chen, Ceshi Chen, Yanxin Li, Haizhong Feng
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-21 (2024)
Abstract Background Cancer stem-like cell is a key barrier for therapeutic resistance and metastasis in various cancers, including breast cancer, yet the underlying mechanisms are still elusive. Through a genome-wide lncRNA expression profiling, we i
Externí odkaz:
https://doaj.org/article/d683b299b311482783d9ef43f7f2af04
Autor:
Tingyue Wu, Wenjing Liu, Hui Chen, Lei Hou, Wenlong Ren, Longlong Zhang, Jinhui Hu, Haijun Chen, Ceshi Chen
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Triple-negative breast cancer (TNBC) is regarded as the deadliest subtype of breast cancer because of its high heterogeneity, aggressiveness, and limited treatment options. Toxoflavin has been reported to possess antitumor activity. In this
Externí odkaz:
https://doaj.org/article/02fe06658cf745deac4a18f1926b57bb
Autor:
Ruipeng Lu, Jingjing Hong, Tong Fu, Yu Zhu, Ruiqi Tong, Di Ai, Shuai Wang, Qingsong Huang, Ceshi Chen, Zhiming Zhang, Rui Zhang, Huiling Guo, Boan Li
Publikováno v:
Advanced Science, Vol 11, Iss 24, Pp n/a-n/a (2024)
Abstract Triple‐negative breast cancer (TNBC), the most aggressive subtype of breast cancer, has a poor prognosis and lacks effective treatment strategies. Here, the study discovered that TNBC shows a decreased expression of epithelial transcriptio
Externí odkaz:
https://doaj.org/article/ab0398d027b94c8ead8e36d482b54297
Autor:
Zhuo Cheng, Maobo Huang, Wei Li, Lei Hou, Li Jin, Qijin Fan, Linqiang Zhang, Chengbin Li, Li Zeng, Chuanyu Yang, Bin Liang, Fubing Li, Ceshi Chen
Publikováno v:
Cell Death and Disease, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract The NLRP3 inflammasome plays an important role in protecting the host from infection and aseptic inflammation, and its regulatory mechanism is not completely understood. Dysregulation of NLRP3 can cause diverse inflammatory diseases. HECTD3
Externí odkaz:
https://doaj.org/article/8b7cb02cb6e6428aa58c29ecd930264c
Autor:
Qiuxia Cui, Jian Sun, Jingping Yuan, Juanjuan Li, Chuanyu Yang, Guangshi Du, Chengang Zhou, Pu Qiu, Jidong Gao, Yuanqi Zhang, Dewei Jiang, Ceshi Chen
Publikováno v:
Genes and Diseases, Vol 11, Iss 1, Pp 91-94 (2024)
Externí odkaz:
https://doaj.org/article/d22b9a91e73b4680b10fa092aabdec8d
Autor:
Zhenbin Wang, Lei Zhang, Bing Li, Jiagui Song, Miao Yu, Jing Zhang, Ceshi Chen, Jun Zhan, Hongquan Zhang
Publikováno v:
Cell Death and Disease, Vol 14, Iss 10, Pp 1-17 (2023)
Abstract Myoepithelium plays an important role in mammary gland development, but less is known about the molecular mechanism underlying how myoepithelium controls acinus differentiation during gestation. Herein, we found that loss of Kindlin-2 in myo
Externí odkaz:
https://doaj.org/article/d497c7d7e5664bf68317baeaea7feaee
Publikováno v:
Cancer Medicine, Vol 12, Iss 15, Pp 16386-16404 (2023)
Abstract Background Breast cancer (BC) seriously threatens women's health. Aspirin plays a key role in the treatment and prognosis of BC. Objective To explore the effect of low‐dose aspirin on BC radiotherapy through the mechanism of exosomes and n
Externí odkaz:
https://doaj.org/article/5f250d58fe5d4b6fab9fe62f44a7a600