Zobrazeno 1 - 10
of 315
pro vyhledávání: '"Cesare Gennari"'
Autor:
Lydia Bisbal Lopez, Domenico Ravazza, Matilde Bocci, Aureliano Zana, Lucrezia Principi, Sheila Dakhel Plaza, Andrea Galbiati, Ettore Gilardoni, Jörg Scheuermann, Dario Neri, Luca Pignataro, Cesare Gennari, Samuele Cazzamalli, Alberto Dal Corso
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Immune-stimulating antibody conjugates (ISACs) equipped with imidazoquinoline (IMD) payloads can stimulate endogenous immune cells to kill cancer cells, ultimately inducing long-lasting anticancer effects. A novel ISAC was designed, featuring the IMD
Externí odkaz:
https://doaj.org/article/b9edd8a96d8444cc849c81174ca18bed
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 5071 (2022)
The human gonadotropin releasing hormone (GnRH-I) and its sea lamprey analogue GnRH-III specifically bind to GnRH receptors on cancer cells and can be used as targeting moieties for targeted tumor therapy. Considering that the selective release of dr
Externí odkaz:
https://doaj.org/article/15d665ff4feb41e794d30225838ed6cc
Autor:
Lizeth Bodero, Paula López Rivas, Barbara Korsak, Torsten Hechler, Andreas Pahl, Christoph Müller, Daniela Arosio, Luca Pignataro, Cesare Gennari, Umberto Piarulli
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 407-415 (2018)
RGD-α-amanitin and isoDGR-α-amanitin conjugates were synthesized by joining integrin ligands to α-amanitin via various linkers and spacers. The conjugates were evaluated for their ability to inhibit biotinylated vitronectin binding to the purified
Externí odkaz:
https://doaj.org/article/b6aac4e1d16e4883ac5787d77551d159
Autor:
Simone Zanella, Gianfranco Bocchinfuso, Marta De Zotti, Daniela Arosio, Franca Marino, Stefano Raniolo, Luca Pignataro, Giovanni Sacco, Antonio Palleschi, Alvaro S. Siano, Umberto Piarulli, Laura Belvisi, Fernando Formaggio, Cesare Gennari, Lorenzo Stella
Publikováno v:
Frontiers in Chemistry, Vol 7 (2019)
Tumor angiogenesis, essential for cancer development, is regulated mainly by vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs), which are overexpressed in cancer cells. Therefore, the VEGF/VEGFR interaction represents a promisi
Externí odkaz:
https://doaj.org/article/a4e1611d36f740098708cafea8c79c51
Autor:
Giovanni Sacco, Daniela Arosio, Mayra Paolillo, Andreas Gloger, Jörg Scheuermann, Luca Pignataro, Laura Belvisi, Alberto Dal Corso, Cesare Gennari
Publikováno v:
Chemistry-A European Journal, 29 (19)
Salicylaldehyde (SA) derivatives are emerging as useful fragments to obtain reversible-covalent inhibitors interacting with the lysine residues of the target protein. Here the SA installation at the C terminus of an integrin-binding cyclopeptide, lea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feb3e17944199a3240f1e4a8b4bc561d
https://hdl.handle.net/20.500.11850/604148
https://hdl.handle.net/20.500.11850/604148
Autor:
Laura Tadiello, Tommaso Gandini, Bernhard M. Stadler, Sergey Tin, Haijun Jiao, Johannes G. de Vries, Luca Pignataro, Cesare Gennari
Publikováno v:
ACS Catalysis. 12:235-246
Autor:
Tommaso Gandini, Luigi Dolcini, Lorenzo Di Leo, Matthieu Fornara, Alberto Bossi, Marta Penconi, Alberto Dal Corso, Cesare Gennari, Luca Pignataro
Publikováno v:
ChemCatChem. 14
Autor:
Alberto Dal Corso, Margaux Frigoli, Martina Prevosti, Mattia Mason, Raffaella Bucci, Laura Belvisi, Luca Pignataro, Cesare Gennari
Publikováno v:
ChemMedChem. 17(15)
Amine-carbamate self-immolative (SI) spacers represent practical and versatile tools in targeted prodrugs, but their slow degradation mechanism limits drug activation at the site of disease. We engineered a pyrrolidine-carbamate SI spacer with a tert
Autor:
Alberto Dal Corso, Cesare Gennari, Laura Belvisi, Simon Stammwitz, Giovanni Sacco, Luca Pignataro
Publikováno v:
European Journal of Organic Chemistry. 2021:1763-1767
Autor:
Cesare Gennari, Luca Pignataro
Publikováno v:
European Journal of Organic Chemistry. 2020:3192-3205