Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Cesar O. Romero"'
Autor:
Sarah R. Anderson, Jacqueline M. Roberts, Jianmin Zhang, Michael R. Steele, Cesar O. Romero, Alejandra Bosco, Monica L. Vetter
Publikováno v:
Cell Reports, Vol 27, Iss 7, Pp 2002-2013.e5 (2019)
Summary: Microglia have important remodeling functions in neurodevelopment, aging, and disease, with evidence for molecular diversity. However, the signaling pathways and environmental cues that drive diverse states of microglia are incompletely unde
Externí odkaz:
https://doaj.org/article/3f807dfbacd947a08f1456532e56880f
Autor:
Alejandra Bosco, Cesar O. Romero, Kevin T. Breen, Alexis A. Chagovetz, Michael R. Steele, Balamurali K. Ambati, Monica L. Vetter
Publikováno v:
Disease Models & Mechanisms, Vol 8, Iss 5, Pp 443-455 (2015)
Microglia serve key homeostatic roles, and respond to neuronal perturbation and decline with a high spatiotemporal resolution. The course of all chronic CNS pathologies is thus paralleled by local microgliosis and microglia activation, which begin at
Externí odkaz:
https://doaj.org/article/106e3c0efa1b4828a68b11cf39462a2b
Autor:
Cesar O. Romero, Michael R. Steele, Sarah R. Anderson, Amanda G. Kautzman, Monica L. Vetter, Jianmin Zhang, Dorothy P. Schafer
Publikováno v:
The Journal of Neuroscience. 39:2025-2040
Microglia play important roles in shaping the developing CNS, and at early stages they have been proposed to regulate progenitor proliferation, differentiation, and neuronal survival. However, these studies reveal contradictory outcomes, highlighting
Autor:
Alejandra Bosco, Michael R. Steele, Cesar O. Romero, William W. Hauswirth, Sanford L. Boye, Kevin T. Breen, Vince A. Chiodo, Sarah R. Anderson, Stephen Tomlinson, Monica L. Vetter
Dysregulation of the complement system is implicated in neurodegeneration, including human and animal glaucoma. Optic nerve and retinal damage in glaucoma is preceded by local complement upregulation and activation, but whether targeting this early i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc1ea28ca67073736646c85b51a0105c
https://doi.org/10.1101/369181
https://doi.org/10.1101/369181
Autor:
Alejandra Bosco, William W. Hauswirth, Sarah R. Anderson, V. Chiodo, Kevin T. Breen, Cesar O. Romero, Sanford L. Boye, Michael R. Steele, Monica L. Vetter, Stephen Tomlinson
Publikováno v:
Acta Ophthalmologica. 95
Autor:
Alejandra Bosco, Sanford Boyle, Monica L. Vetter, William W. Hauswirth, Stephen Tomlinson, Kevin T. Breen, Cesar O. Romero, Vince A. Chiodo, Sarah R. Anderson, Michael R. Steele
Publikováno v:
Molecular Immunology. 102:136
Publikováno v:
Journal of visualized experiments : JoVE. (99)
Microglia, which are CNS-resident neuroimmune cells, transform their morphology and size in response to CNS damage, switching to an activated state with distinct functions and gene expression profiles. The roles of microglial activation in health, in
Autor:
Cesar O. Romero, Denise M. Inman, Alejandra Bosco, Samuel D. Crish, Philip J. Horner, Monica L. Vetter, Michael R. Steele, David J. Calkins
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43602 (2012)
PLoS ONE
PLoS ONE
Glaucoma is a neurodegenerative disease that results in the progressive decline and ultimate death of retinal ganglion cells (RGCs). While multiple risk factors are associated with glaucoma, the mechanisms leading to onset and progression of the dise
Autor:
Alejandra Bosco, Samuel D Crish, Michael R Steele, Cesar O Romero, Denise M Inman, Philip J Horner, David J Calkins, Monica L Vetter
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43602 (2012)
Glaucoma is a neurodegenerative disease that results in the progressive decline and ultimate death of retinal ganglion cells (RGCs). While multiple risk factors are associated with glaucoma, the mechanisms leading to onset and progression of the dise
Externí odkaz:
https://doaj.org/article/3a10033f1acd459c89a9afb505aa51fa