Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Cesar Mendoza-Martinez"'
Design of the Global Health chemical diversity library v2 for screening against infectious diseases.
Autor:
Caroline Wilson, J Mark F Gardner, David W Gray, Beatriz Baragana, Paul G Wyatt, Alex Cookson, Stephen Thompson, Cesar Mendoza-Martinez, Michael J Bodkin, Ian H Gilbert, Gary J Tarver
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 12, p e0011799 (2023)
There is a need for novel chemical matter for phenotypic and target-based screens to find starting points for drug discovery programmes in neglected infectious diseases and non-hormonal contraceptives that disproportionately affect Low- and Middle-In
Externí odkaz:
https://doaj.org/article/ae7dc23b661c42e4b35f3b3a4b1a1f7f
An in-silico drug repurposing study was carried out to search for potential COVID-19 antiviral agents. A dataset of 1615 FDA-approved drugs was docked in the active site of SARS CoV-2 Main protease. A subset of the top scoring hit compounds was subje
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2771e41983170bc3a48fb62887befd96
https://doi.org/10.26434/chemrxiv.12085083
https://doi.org/10.26434/chemrxiv.12085083
Autor:
Juan L. Bautista, Hugo Torrens, Martha Irene Bucio Torres, Adriana Moreno-Rodríguez, Eduardo Pérez-Campos, Francisco Hernández-Luis, Yolanda Guevara-Gómez, Margarita Cabrera-Bravo, Cesar Mendoza Martinez, Socorro Pina-Canseco, Paz María Salazar-Schettino
Publikováno v:
European journal of medicinal chemistry. 87
In this study thiosemicarbazones derivatives of 5-[(trifluoromethyl)phenylthio]-2-furaldehyde were synthesized and evaluated in terms of their efficiency in challenging the growth of epimastigote forms of Trypanosoma cruzi, the etiological agent of C