Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Cesar M. Castro"'
Autor:
Judith Owokuhaisa, Eleanor Turyakira, Frank Ssedyabane, Deusdedit Tusubira, Rogers Kajabwangu, Pius Musinguzi, Martin Galiwango, Thomas C. Randall, Nathan Kakongi, Cesar M. Castro, Esther C. Atukunda, Samuel Maling
Publikováno v:
BMC Women's Health, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Cervical cancer continues to threaten women’s health, especially in low-resource settings. Regular follow-up after screening and treatment is an effective strategy for monitoring treatment outcomes. Consequently, understanding t
Externí odkaz:
https://doaj.org/article/003e32bc14c34964b940149f23162150
Autor:
Chang Yeol Lee, Hyunho Kim, Ismail Degani, Hanna Lee, Angel Sandoval, Yoonho Nam, Madeleine Pascavis, Hyun Gyu Park, Thomas Randall, Amy Ly, Cesar M. Castro, Hakho Lee
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Addressing the global disparity in cancer care necessitates the development of rapid and affordable nucleic acid (NA) testing technologies. This need is particularly critical for cervical cancer, where molecular detection of human papillomav
Externí odkaz:
https://doaj.org/article/0a51e6d890024649915f9b853635ae23
Autor:
Frank Ssedyabane, Ekwaro A. Obuku, Eve Namisango, Joseph Ngonzi, Cesar M. Castro, Hakho Lee, Thomas C. Randall, Moses Ocan, Robert Apunyo, Alison Annet Kinengyere, Rogers Kajabwangu, Aziza Tahirah Kisawe, Josephine Nambi Najjuma, Deusdedit Tusubira, Nixon Niyonzima
Publikováno v:
Gynecologic Oncology Reports, Vol 54, Iss , Pp 101424- (2024)
Studies suggest a need for new diagnostic approaches for cervical cancer including microRNA technology. In this review, we assessed the diagnostic accuracy of microRNAs in detecting cervical cancer and Cervical Intraepithelial Neoplasia (CIN).We perf
Externí odkaz:
https://doaj.org/article/12118b25f4dc4bcfa0cfd64419c738a3
Autor:
Ala Jo, Allen Green, Jamie E. Medina, Sonia Iyer, Anders W. Ohman, Eric T. McCarthy, Ferenc Reinhardt, Thomas Gerton, Daniel Demehin, Ranjan Mishra, David L. Kolin, Hui Zheng, Jinwoo Cheon, Christopher P. Crum, Robert A. Weinberg, Bo R. Rueda, Cesar M. Castro, Daniela M. Dinulescu, Hakho Lee
Publikováno v:
Advanced Science, Vol 10, Iss 27, Pp n/a-n/a (2023)
Abstract Detecting early cancer through liquid biopsy is challenging due to the lack of specific biomarkers for early lesions and potentially low levels of these markers. The current study systematically develops an extracellular‐vesicle (EV)‐bas
Externí odkaz:
https://doaj.org/article/80311c6a1d4e4c65b0abe22c8b14a2e5
Publikováno v:
Advanced Science, Vol 10, Iss 24, Pp n/a-n/a (2023)
Abstract MicroRNAs (miRNAs) in extracellular vesicles (EVs) play essential roles in cancer initiation and progression. Quantitative measurements of EV miRNAs are critical for cancer diagnosis and longitudinal monitoring. Traditional PCR‐based metho
Externí odkaz:
https://doaj.org/article/6a3f9078083241228f9217e58d02eeb6
Autor:
Yoon Ho Roh, Chang Yeol Lee, Sujin Lee, Hyunho Kim, Amy Ly, Cesar M. Castro, Jinwoo Cheon, Jae‐Hyun Lee, Hakho Lee
Publikováno v:
Advanced Science, Vol 10, Iss 10, Pp n/a-n/a (2023)
Abstract CRISPR/Cas systems offer a powerful sensing mechanism to transduce sequence‐specific information into amplified analytical signals. However, performing multiplexed CRISPR/Cas assays remains challenging and often requires complex approaches
Externí odkaz:
https://doaj.org/article/94aaa91e95774326bb16b11bbcdd4f4b
Autor:
Mi Ho Jeong, Taehwang Son, Yoo Keung Tae, Chan Hee Park, Hee Seung Lee, Moon Jae Chung, Jeong Youp Park, Cesar M. Castro, Ralph Weissleder, Jung Hyun Jo, Seungmin Bang, Hyungsoon Im
Publikováno v:
Advanced Science, Vol 10, Iss 8, Pp n/a-n/a (2023)
Abstract Cholangiocarcinoma (CCA) is a fatal disease often detected late in unresectable stages. Currently, there are no effective diagnostic methods or biomarkers to detect CCA early with high confidence. Analysis of tumor‐derived extracellular ve
Externí odkaz:
https://doaj.org/article/6a8e772253d948e1a88dc417532279e8
Autor:
Edmund J. Keliher, Thomas Reiner, Sarah Earley, Jenna Klubnick, Carlos Tassa, Andrew J. Lee, Sridhar Ramaswamy, Nabeel Bardeesy, Douglas Hanahan, Ronald A. DePinho, Cesar M. Castro, Ralph Weissleder
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 15, Iss 7, Pp 684-693 (2013)
When resectable, invasive pancreatic ductal adenocarcinoma (PDAC) is most commonly treated with surgery and radiochemotherapy. Given the intricate local anatomy and locoregional mode of dissemination, achieving clean surgical margins can be a signifi
Externí odkaz:
https://doaj.org/article/937c1a9d4cf24cadbd48cb4cc2afc3f2
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 5, Pp 388-395 (2012)
Identifying circulating tumor cells (CTCs) with greater sensitivity could facilitate early detection of cancer and rapid assessment of treatment response. Most current technologies use EpCAM expression as a CTC identifier. However, given that a signi
Externí odkaz:
https://doaj.org/article/2242c440a5a24f11862b130016408338
Autor:
Lip Ket Chin, Jun-Yeong Yang, Benjamin Chousterman, Sunghoon Jung, Do-Geun Kim, Dong-Ho Kim, Seunghun Lee, Cesar M. Castro, Ralph Weissleder, Sung-Gyu Park, Hyungsoon Im
Publikováno v:
ACS Nano
Rapid, sensitive, simultaneous quantification of multiple biomarkers in point-of-care (POC) settings could improve the diagnosis and management of sepsis, a common, potentially life-threatening condition. Compared to high-end commercial analytical sy