Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Cesar Jacintho Moritz"'
Publikováno v:
Physiology. 38
Doxorubicin (DOX)-induced cardiotoxicity results in an increased risk of mortality among chemotherapy recipients. Cardiomyocyte dysfunction is caused by the off-target accumulation of DOX in cardiac mitochondria, stimulating oxidative damage and impa
Autor:
Vivian Doerr, Ryan Montalvo, Cesar Jacintho Moritz, Franccesco Boeno, Imtiaz Dowllah, Ashley Smuder
Publikováno v:
Physiology. 38
Doxorubicin (DOX) is a highly effective chemotherapeutic used in cancer treatment. However, its use is associated with the development of cardiac dysfunction, which can negatively affect patient outcomes and reduce overall survival. While no clinical