Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Cerys E Currie"'
Autor:
Cerys E. Currie, Emma Ford, Lucy Benham Whyte, Deborah M. Taylor, Bettina P. Mihalas, Muriel Erent, Adele L. Marston, Geraldine M. Hartshorne, Andrew D. McAinsh
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Human beings arise from serial mitotic divisions of a single fertilised egg. Here through live cell imaging of fertilized embryos the authors show that the first mitotic division is error prone and can contribute to preimplantation mosaicism.
Externí odkaz:
https://doaj.org/article/070a5d4d39354b38a6e1e9964ca0f05e
Autor:
Bettina P Mihalas, Gerard H Pieper, Cerys E Currie, David A Kelly, Geraldine M Hartshorne, Andrew D McAinsh, Richard A Anderson, Adele L Marston
Aneuploid human eggs (oocytes) are a major cause of infertility, miscarriage and chromosomal disorders. Such aneuploidies increase greatly as women age, originating from defective linkages between sister-chromatids (cohesion) in meiosis. We found evi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8aba372407f70b532f47644e9d946d2
https://doi.org/10.1101/2023.01.13.523952
https://doi.org/10.1101/2023.01.13.523952
Autor:
Cerys E. Currie, Emma Ford, Deborah M. Taylor, Andrew D. McAinsh, Muriel Erent, Adele L. Marston, Geraldine M. Hartshorne
Aneuploidy in human embryos is surprisingly prevalent and increases drastically with maternal age, resulting in miscarriages, infertility and birth defects. Frequent errors during the meiotic divisions cause this aneuploidy, while age-independent err
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3df264913dcf751a81b68fe05ac271d5
https://doi.org/10.1101/2020.07.17.208744
https://doi.org/10.1101/2020.07.17.208744
Autor:
Jonathan B. A. Millar, Cerys E. Currie, Christopher A. Smith, Mar Mora-Santos, Andrew D. McAinsh
Publikováno v:
Current biology : CB. 28(17)
Error-free chromosome segregation during mitosis depends on a functional spindle assembly checkpoint (SAC). The SAC is a multi-component signalling system that is recruited to unattached or incorrectly attached kinetochores to catalyse the formation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec6258718d82a0aa21149034c51fa45c
https://pubmed.ncbi.nlm.nih.gov/30205061
https://pubmed.ncbi.nlm.nih.gov/30205061
Autor:
Jonathan B. A. Millar, Andrew D. McAinsh, Christopher A. Smith, Cerys E. Currie, Maria Dm Mora-Santos
Error-free chromosome segregation during mitosis depends on a functional spindle assembly checkpoint (SAC). The SAC is a multi-component signaling system that is recruited to incorrectly attached kinetochores to catalyze the formation of a soluble in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5454b7dc83f718f39f95660f75c23e68
https://doi.org/10.1101/278820
https://doi.org/10.1101/278820