Nucleoside hydrolase immobilized on magnetic particles as a tool for onflow screening and characterization of inhibitors.

Autor: de Oliveira PCO; BioCrom, Organic Chemistry Department, Chemistry Institute, Fluminense Federal University, Niterói, RJ, Brazil., Ceroullo MS; BioCrom, Organic Chemistry Department, Chemistry Institute, Fluminense Federal University, Niterói, RJ, Brazil., Dos Santos MB; LNHC, Organic Chemistry Department, Chemistry Institute, Fluminense Federal University, Niterói, RJ, Brazil., Medeiros PRC; BioCrom, Organic Chemistry Department, Chemistry Institute, Fluminense Federal University, Niterói, RJ, Brazil., Marques BCB; Laboratory for Analysis and Development of Enzyme Inhibitors, Natural Products Research Institute, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil., Tinoco LW; Laboratory for Analysis and Development of Enzyme Inhibitors, Natural Products Research Institute, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil., de Souza MCBV; LNHC, Organic Chemistry Department, Chemistry Institute, Fluminense Federal University, Niterói, RJ, Brazil., da Costa Santos Boechat F; LNHC, Organic Chemistry Department, Chemistry Institute, Fluminense Federal University, Niterói, RJ, Brazil., de Moraes MC; BioCrom, Organic Chemistry Department, Chemistry Institute, Fluminense Federal University, Niterói, RJ, Brazil. Electronic address: mcmoraes@id.uff.br.

Publikováno v: Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2023 Oct 25; Vol. 235, pp. 115589. Date of Electronic Publication: 2023 Jul 20.