Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Ceri H. Davies"'
Publikováno v:
Journal of Pharmacological Sciences, Vol 95, Iss 2, Pp 240-247 (2004)
We examined if a range of carbonic anhydrase inhibitors (CAIs) interacted with the high-voltage activated voltage-sensitive calcium channels (VSCCs) encoded by the human α1E subunit. Whole-cell recordings were made from HEK293 cells stably expressin
Externí odkaz:
https://doaj.org/article/49509ac95eb645c5be8205fc9a5d3569
Autor:
Rebecca Evans, Haruhide Kimura, Robert Alexander, Ceri H. Davies, Hélène Faessel, Deborah S. Hartman, Takashi Ishikawa, Emiliangelo Ratti, Kohei Shimizu, Motohisa Suzuki, Shinichiro Tanaka, Hiroshi Yukitake, Yves Dauvilliers, Emmanuel Mignot
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Narcolepsy type 1 (NT1) is a sleep disorder caused by a loss of orexinergic neurons. Narcolepsy type 2 (NT2) is heterogeneous; affected individuals typically have normal orexin levels. Following evaluation in mice, the effects of the orexin 2 recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2359c6452ab5701e434a27ca5102585
https://doi.org/10.1073/pnas.2207531119
https://doi.org/10.1073/pnas.2207531119
Autor:
Elizabeth Tilley, Caroline M. Voss, Douglass M. Turnbull, Nichola Z. Lax, Zoe Powell, Mark O. Cunningham, Blanca I. Aldana, Sophie Nichols, Ceri H. Davies, Alistair Jenkins, Shuna Whyte, Felix Chan, Claire Nicholson, Helle S. Waagepetersen
Publikováno v:
Brain. 142:391-411
Approximately one-quarter of patients with mitochondrial disease experience epilepsy. Their epilepsy is often severe and resistant towards conventional antiepileptic drugs. Despite the severity of this epilepsy, there are currently no animal models a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c142aaee585b28d68c12ad95346f158f
https://doi.org/10.1093/brain/awy320
https://doi.org/10.1093/brain/awy320
Autor:
Katherine L. Gibbs, Bernadett Kalmar, Elena R. Rhymes, Alexander D. Fellows, Mahmood Ahmed, Paul Whiting, Ceri H. Davies, Linda Greensmith, Giampietro Schiavo
Publikováno v:
Cell Death and Disease, Vol 9, Iss 6, Pp 1-16 (2018)
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease caused by the degeneration of upper and lower motor neurons. Defects in axonal transport have been observed pre-symptomatically in the SOD1G93A mouse model of ALS, and have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::97f2de01ae7ab163f73455b34d387e4b
http://link.springer.com/article/10.1038/s41419-018-0624-8
http://link.springer.com/article/10.1038/s41419-018-0624-8
Autor:
Anita K Roopun, Mark A Kramer, Lucy M Carracedo, Marcus Kaiser, Ceri H Davies, Roger D Traub, Nancy J Kopell, Miles A Whittington
Publikováno v:
Frontiers in Neuroscience, Vol 2 (2008)
Multiple local neuronal circuits support different, discrete frequencies of network rhythm in neocortex. Relationships between different frequencies correspond to mechanisms designed to minimise interference, couple activity via stable phase interact
Externí odkaz:
https://doaj.org/article/3427d75dd1c448f28ea5dea88e3d67b4
Autor:
Claudia Racca, Martin J. Gillies, Steven J. Middleton, Fiona E. N. LeBeau, Andrea Bibbig, Ceri H. Davies, Miles A. Whittington, H.L. Garner
Generation of gamma rhythms in reciprocally connected areas of cortex produces synchronous neuronal firing, although little is known about the consequences of gamma rhythms when generated in nonreciprocally connected regions. This nonreciprocity exis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07333853183951408dc1832535d94201
https://ora.ox.ac.uk/objects/uuid:c1a94c06-2896-4263-b1df-622a6da19b60
https://ora.ox.ac.uk/objects/uuid:c1a94c06-2896-4263-b1df-622a6da19b60
Autor:
Laura Rosen, Ceri H. Davies, Venkatesha Murthy, Robert Alexander, Emiliangelo Ratti, Patricio O'Donnell
Publikováno v:
International Journal of Neuropsychopharmacology
The paucity of novel drugs for neuropsychiatric indications contrasts with the remarkable recent advances in neuroscience research. We have identified 5 challenges the field needs to address and recommend potential solutions. First, we need to drive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf2503b1cbbe3a2340296b43eafdaa87
https://doi.org/10.1093/ijnp/pyz027
https://doi.org/10.1093/ijnp/pyz027
Autor:
Theodore Brookings, Michael F. Murphy, Graham T. Dempsey, Owen B. McManus, Luis A. Williams, Vaibhav Joshi, Ceri H. Davies, Christopher A. Werley, Johannes Grosse, John Ferrante
Publikováno v:
Neurochemical research. 44(3)
Induced pluripotent stem (iPS) cells offer the exciting opportunity for modeling neurological disorders in vitro in the context of a human genetic background. While significant progress has been made in advancing the use of iPS cell-based disease mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d885ea95c40fee7cbe17d35dfd2875f
https://pubmed.ncbi.nlm.nih.gov/30603979
https://pubmed.ncbi.nlm.nih.gov/30603979
Autor:
Wheaton Little, Ceri H. Davies
Publikováno v:
Neuropharmacology. 120
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de2d454ff53d43337851456fcd5e3d1c
https://pubmed.ncbi.nlm.nih.gov/28476641
https://pubmed.ncbi.nlm.nih.gov/28476641
Autor:
Paul Bryan Wren, Roberto Arban, Frank A Gray, Ceri H. Davies, Dino Montanari, Jessica L. Schneck, T. Gregg Davis, A. Richard Rutter, Michele Negri, Palmina Cavallini, Alessandro Poffe, Elena Vicentini
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 350:153-163
Small molecule phosphodiesterase (PDE) 4 inhibitors have long been known to show therapeutic benefit in various preclinical models of psychiatric and neurologic diseases because of their ability to elevate cAMP in various cell types of the central ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ec1494680d1840df35a21a219888b5f
https://doi.org/10.1124/jpet.114.214155
https://doi.org/10.1124/jpet.114.214155