Výsledky vyhledávání - "Ceren G. Korkmaz"

ANALYSIS OF ANDROGEN REGULATED HOMEOBOX GENE NKX3.1 DURING PROSTATE CARCINOGENESIS

Autor: Zhijun Xi, Björn Risberg, Ceren G. Korkmaz, Massimo Loda, Håvard E. Danielsen, Kemal Sami Korkmaz, Janet Kung, William R. Sellers, Judith Manola, Fahri Saatcioglu

Publikováno v: Journal of Urology. 172:1134-1139

NKX3.1 is an androgen regulated gene that is largely specific to the prostate for expression and it is predicted to encode a homeobox protein. Null alleles of NKX3.1 in mice results in impaired prostate development as well as hyperplasia and dysplasi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7b509a94992da6e5deca14787de39e0
https://doi.org/10.1097/01.ju.0000136526.78535.b8

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Potentiation of androgen receptor transcriptional activity by inhibition of histone deacetylation--rescue of transcriptionally compromised mutants

Autor: Katrine Frønsdal, Y Zhang, Ceren G. Korkmaz, Petra Isabel Lorenzo, Fahri Saatcioglu

Publikováno v: Journal of Endocrinology. 182:377-389

Androgens are critical in the development and maintenance of the male reproductive system and important in the progression of prostate cancer. The effects of androgens are mediated by the androgen receptor (AR), which is a ligand-modulated transcript

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3a65edf1978bce7c0c045c3df0a4229
https://doi.org/10.1677/joe.0.1820377

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Molecular Cloning and Characterization of STAMP1, a Highly Prostate-specific Six Transmembrane Protein that Is Overexpressed in Prostate Cancer

Autor: Massimo Loda, Fahri Saatcioglu, Kemal Sami Korkmaz, Gordon L. Hager, Ceren G. Korkmaz, Cem Elbi

Publikováno v: Journal of Biological Chemistry. 277:36689-36696

We have identified a novel gene, six transmembrane protein of prostate 1 (STAMP1), which is largely specific to prostate for expression and is predicted to code for a 490-amino acid six transmembrane protein. Using a form of STAMP1 labeled with green

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8d7017eeff74089a606eac309ea6bd9
https://doi.org/10.1074/jbc.m202414200

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Molecular cloning and characterization of STAMP2, an androgen-regulated six transmembrane protein that is overexpressed in prostate cancer

Autor: Ceren G. Korkmaz, Kemal Sami Korkmaz, Tove Irene Klokk, Piotr Kurys, Clara Hammarström, Ling Wang, Gunhild Trøen, Cem Elbi, Aud Svindland, Fahri Saatcioglu, Gordon L. Hager

Publikováno v: Oncogene. 24(31)

We have identified a novel gene, six transmembrane protein of prostate 2 (STAMP2), named for its high sequence similarity to the recently identified STAMP1 gene. STAMP2 displays a tissue-restricted expression with highest expression levels in placent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::879eed33fac9a25407e594aa102ea290
https://pubmed.ncbi.nlm.nih.gov/15897894

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NKX3.1 expression is lost in testicular germ cell tumors

Autor: Ceren G. Korkmaz, Vera M. Abeler, Fahri Saatcioglu, Tove Irene Klokk, Rolf Inge Skotheim, Kemal Sami Korkmaz, Jahn M. Nesland, Sophie D. Fosså, Ragnhild A. Lothe

Publikováno v: The American journal of pathology. 163(6)

NKX3.1 is a homeobox gene which exhibits prostate and testis specific expression. Loss of NKX3.1 expression has been implicated in prostate development and tumorigenesis, but the role of NKX3.1 in testis biology is not known. Here we show that NKX3.1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e3c5148ed89da6784d869427dc3f40f
https://pubmed.ncbi.nlm.nih.gov/14633588

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Distinctly different gene structure of KLK4/KLK-L1/prostase/ARM1 compared with other members of the kallikrein family: intracellular localization, alternative cDNA forms, and Regulation by multiple hormones

Autor: Ceren G. Korkmaz, Kemal Sami Korkmaz, Fahri Saatcioglu, Thomas G. Pretlow

Publikováno v: DNA and cell biology. 20(7)

The tissue kallikreins (KLKs) form a family of serine proteases that are involved in processing of polypeptide precursors and have important roles in a variety of physiologic and pathological processes. Common features of all tissue kallikrein genes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::872b28697f4178fdc49b5811ac76d896
https://pubmed.ncbi.nlm.nih.gov/11506707

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C-Jun N-terminal kinase is required for phorbol ester- and thapsigargin-induced apoptosis in the androgen responsive prostate cancer cell line LNCaP

Autor: Nikolai Engedal, Ceren G. Korkmaz, Fahri Saatcioglu

Publikováno v: Oncogene. 21(7)

In early, androgen dependent stages of prostate cancer, androgen withdrawal, the major course of therapy in prostate cancer, leads to a rapid regression of the tumor as a result of apoptosis. However, prostate cancer invariably progresses to an andro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::625a77c72fd3938fd81720712fe08b5f
https://pubmed.ncbi.nlm.nih.gov/11850819

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An efficient procedure for cloning hormone-responsive genes from a specific tissue

Autor: Erlend Ragnhildstveit, Kemal Sami Korkmaz, Ceren G. Korkmaz, Fahri Saatcioglu, Thomas G. Pretlow

Publikováno v: DNA and cell biology. 19(8)

Nuclear receptors form a superfamily of ligand-activated transcription factors. In contrast to the significant advances made in recent years to dissect nuclear receptor structure and their corresponding function, progress has been rather slow in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a464a854b9c86ed07c1439a29bc70a37
https://pubmed.ncbi.nlm.nih.gov/10975467

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