Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Cerebrospinal fluid penetration"'
Akademický článek
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Autor:
João Paulo Telles, Felipe Francisco Tuon, Victoria Stadler Tasca Ribeiro, Carolina Hikari Yamada, Juliano Gasparetto, Juliette Cieslinski, Dayana Dos Santos Oliveira
Publikováno v:
Therapeutic Drug Monitoring. 43:807-811
Background This study aimed to evaluate the utility of a commercial kit used to measure serum vancomycin concentrations to determine vancomycin concentrations in cerebrospinal fluid (CSF) samples and evaluate CSF penetration when administered as a co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb61f0fa55461262862a26d8d6d90e71
https://doi.org/10.1097/ftd.0000000000000907
https://doi.org/10.1097/ftd.0000000000000907
Akademický článek
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Publikováno v:
J Pediatr Pharmacol Ther
Pharmacokinetic data regarding ceftaroline fosamil (CPT) penetration into cerebrospinal fluid (CSF) are limited to a rabbit model (15% inflamed) and adult case reports. We describe serum and CSF CPT concentrations in a 21-year-old, 34.8 kg female, me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0963aefb0424449ffb4c884de9fb8e18
https://doi.org/10.5863/1551-6776-25.4.336
https://doi.org/10.5863/1551-6776-25.4.336
Autor:
Cody J. Peer, William D. Figg, Priya Shankarappa, Cynthia McCully, Rafael C. Garcia, Arman Odabas, Katherine E. Warren
Publikováno v:
Cancer Chemother Pharmacol
PURPOSE: Pexidartinib (PLX3397) is a colony-stimulating factor-1 receptor (CSF-1R) inhibitor under clinical evaluation for potential CNS tumor treatment. This study aims to evaluate plasma pharmacokinetic parameters and estimate CNS penetrance of pex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c5710742a7f5b902c1e2b55637e5722
https://doi.org/10.1007/s00280-020-04071-7
https://doi.org/10.1007/s00280-020-04071-7
Autor:
Hiroyuki Yamaguchi, Keisuke Kirita, Nobuyuki Yamamoto, Takayuki Suetsugu, Kazushige Wakuda, Kenji Chibana, Yuki Nakatani, Toshihide Yokoyama, Noriyuki Ebi, Kohji Inoue, Hirotsugu Kenmotsu, Kenji Sugio, Taishi Harada, Hiroshi Mukae, Kenichi Yoshimura, Kentaro Tanaka, Kazuhiko Nakagawa, Satoru Miura, Minoru Fukuda, Kentaro Ito
Publikováno v:
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 16(12)
Objectives Osimertinib has been reported to be effective against central nervous system (CNS) metastasis from activating EGFR mutation-positive NSCLC. Nevertheless, the true antitumor effects of osimertinib alone for CNS metastasis are unclear becaus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a977e035074b3403883e676c449fbf11
https://pubmed.ncbi.nlm.nih.gov/34419684
https://pubmed.ncbi.nlm.nih.gov/34419684
Autor:
Melissa Lassig-Smith, Jeffrey Lipman, Fekade B. Sime, Janine Stuart, Suzanne L. Parker, Saurabh Pandey, Jason A. Roberts, Steven C. Wallis, Therese Starr
Publikováno v:
Antimicrobial Agents and Chemotherapy
The aim of this study was to describe the pharmacokinetics of ceftolozane-tazobactam in plasma and cerebrospinal fluid (CSF) of infected critically ill patients. In a prospective observational study, critically ill patients (≥18 years) with an indw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc4c080ebfb40a7438c68f571c849155
https://doi.org/10.1128/aac.01698-20
https://doi.org/10.1128/aac.01698-20
Autor:
James R. Woodworth, Michael L. Zeckel
This chapter seeks to provide an overview of clinically useful information regarding the pharmacokinetics, clinical uses, and safety profile of vancomycin. Vancomycin exhibits poor oral bioavailability. Following oral administration, only trace amoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ca6168a610d58c03cc3b2b7d2217507
https://doi.org/10.1201/9781003067269-9
https://doi.org/10.1201/9781003067269-9
Autor:
Takeshi Kitazaki, Takashi Seto, Noriyuki Ebi, Taishi Harada, Takeharu Yamanaka, Kenji Sugio, Yoshimasa Shiraishi, Daisuke Himeji, Mitsuhiro Takenoyama, Akinobu Hamada, Takayuki Shimose, Kaname Nosaki
Publikováno v:
Oncologist
Lessons Learned This phase II trial evaluated the efficacy of erlotinib for patients with non-small cell lung cancer with leptomeningeal metastasis. The 17 cerebrospinal fluid specimens that were available for epidermal growth factor receptor mutatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::451063f262e9827092f94c45bac62a34
https://pubmed.ncbi.nlm.nih.gov/32654250
https://pubmed.ncbi.nlm.nih.gov/32654250
Autor:
Eiichi Ishii, Kyoko Moritani, Kozo Nagai, Hisamichi Tauchi, Toshihiro Jogamoto, Takahiro Motoki, Kaori Aibara, Fumihiro Ochi, Mari Tezuka
Publikováno v:
Clinical Pediatrics. 57:1672-1676
We evaluated the efficacy of linezolid treatment in 6 children with health care–associated meningitis or ventriculitis (HCAMV) caused by gram-positive cocci. All children were diagnosed and treated at the Ehime University Hospital between January 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a47fb98cc437e608e4a84e6615b37d46
https://doi.org/10.1177/0009922818803399
https://doi.org/10.1177/0009922818803399