Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Cerdulatinib"'
Autor:
Ana M. Montilla, Francisco Gómez-García, Pedro J. Gómez-Arias, Jesús Gay-Mimbrera, Jorge Hernández-Parada, Beatriz Isla-Tejera, Juan Ruano
Publikováno v:
Dermatology and Therapy, Vol 9, Iss 4, Pp 655-683 (2019)
Abstract Introduction The JAK/STAT signaling pathway is involved in the immune-mediated inflammatory skin diseases atopic dermatitis (AD), vitiligo, and alopecia areata (AA), and represents a potential target when developing treatments. So far, no dr
Externí odkaz:
https://doaj.org/article/932be4320b3e4bceb4c9a6db40a9c81e
Akademický článek
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Autor:
Ning Zhang, John E. Jett, Dawn Gillmor, Kimberly McHale, Stephen Piscitelli, Randall Li, Ana B. Pavel, Jon Collins, Emma Guttman-Yassky, T. Song, Anna M. Tallman, Glenn Tabolt
Publikováno v:
Journal of Investigative Dermatology. 141:1847-1851
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1db8cb02b4358230baae9841b18a1a9e
https://doi.org/10.1016/j.jid.2020.11.031
https://doi.org/10.1016/j.jid.2020.11.031
Autor:
Antoine Wagner, Michèle Rouleau, Lyne Villeneuve, Trang Le, Cheryl Peltier, Éric P. Allain, Caroline Beaudoin, Sophie Tremblay, Fréderic Courtier, Flora Nguyen Van Long, Isabelle Laverdière, Éric Lévesque, Versha Banerji, Katrina Vanura, Chantal Guillemette
Publikováno v:
Cells; Volume 12; Issue 9; Pages: 1295
In chronic lymphocytic leukemia (CLL), an elevated glycosyltransferase UGT2B17 expression (UGT2B17HI) identifies a subgroup of patients with shorter survival and poor drug response. We uncovered a mechanism, possibly independent of its enzymatic func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c8d2439a5a40b2352b3e14d2917e446
https://doi.org/10.3390/cells12091295
https://doi.org/10.3390/cells12091295
Publikováno v:
Allergologie Select
The JAK-STAT pathway is involved in the signaling of multiple cytokines driving cutaneous inflammation in atopic dermatitis (AD). Janus kinase (JAK) inhibitors target individual receptor-associated kinases, thereby preventing the mediation of inflamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f7155655f1eacf42a8080701a668312
https://pubmed.ncbi.nlm.nih.gov/34532638
https://pubmed.ncbi.nlm.nih.gov/34532638
Autor:
Beatriz Isla-Tejera, Juan Ruano, Ana Montilla, Jorge Hernández-Parada, Francisco Gómez-García, Pedro Jesús Gómez-Arias, Jesús Gay-Mimbrera
Publikováno v:
Dermatology and Therapy
Dermatology and Therapy, Vol 9, Iss 4, Pp 655-683 (2019)
Dermatology and Therapy, Vol 9, Iss 4, Pp 655-683 (2019)
Introduction The JAK/STAT signaling pathway is involved in the immune-mediated inflammatory skin diseases atopic dermatitis (AD), vitiligo, and alopecia areata (AA), and represents a potential target when developing treatments. So far, no drugs targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::184e5993e73e294a96cd8afb909c2147
https://doi.org/10.1007/s13555-019-00329-y
https://doi.org/10.1007/s13555-019-00329-y
Publikováno v:
Microorganisms, Vol 8, Iss 1743, p 1743 (2020)
Microorganisms
Microorganisms
A common disease worldwide is known as atopic dermatitis (AD), named also as atopic eczema, which is a chronic recurrent complex inflammatory skin disorder. It affects 2–10% of the adult population and up to 20% of the pediatric population. The cli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11a0a9af14dcfff6734a7ebc27cdb84a
https://www.mdpi.com/2076-2607/8/11/1743
https://www.mdpi.com/2076-2607/8/11/1743
Autor:
Muhtarjan Osman, Manish R. Patel, Stephen D. Smith, Greg Coffey, Cristina B Guzman, Javier Munoz, Don A. Stevens, Tatyana Feldman, Brian T. Hess, Jaymes S Holland, Paul A. Hamlin, Sonali M. Smith
Publikováno v:
Blood. 138:2423-2423
Background Relapsed/refractory follicular lymphoma (FL) is a challenging disease; novel therapeutics with different mechanisms of action are needed. Spleen tyrosine kinase (SYK) and Janus kinase (JAK) signaling pathways are activated in FL and appear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a54e4b03f1f1f2adf852dc9c163db0f7
https://doi.org/10.1182/blood-2021-148313
https://doi.org/10.1182/blood-2021-148313
Autor:
Manish R. Patel, Sonali M. Smith, Cristina B Guzman, Jing C. Ye, Youn H. Kim, Tatyana Feldman, Muhtarjan Osman, Michael S. Khodadoust, Ryan A. Wilcox, Steven M. Horwitz, Paul A. Hamlin, Jaymes S Holland, Javier Munoz, Greg Coffey
Publikováno v:
Blood. 138:622-622
Background Peripheral T-cell lymphoma (PTCL) comprises a heterogeneous group of T-cell non-Hodgkin's lymphomas with poor prognosis that are often refractory to treatment. Spleen tyrosine kinase (SYK) and Janus kinase (JAK) signaling pathways are impo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa60bc2b179e090e14f440a4294b2f74
https://doi.org/10.1182/blood-2021-148352
https://doi.org/10.1182/blood-2021-148352
Publikováno v:
Oncotarget
// Ailin Guo 1,* , Pin Lu 1,* , Greg Coffey 2 , Pamela Conley 2 , Anjali Pandey 2 and Y. Lynn Wang 1 1 Department of Pathology, Lymphoma Translational Pathology, University of Chicago, Chicago, IL, USA 2 Portola Pharmaceuticals, Inc., South San Franc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ebd69bbbc14f19d6c00d24b711ead6b
https://doi.org/10.18632/oncotarget.14588
https://doi.org/10.18632/oncotarget.14588