Zobrazeno 1 - 10 of 221 pro vyhledávání: '"Cerda-Nicolas M"'
1
Matched Paired Primary and Recurrent Meningiomas Points to Cell-Death Program Contributions to Genomic and Epigenomic Instability along Tumor Progression
Autor: San-Miguel T, Megias J, Monleon D, Navarro L, Munoz-Hidalgo L, Montoliu C, Meri M, Roldan P, Cerda-Nicolas M, Lopez-Gines C
Publikováno v: Cancers
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
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Meningioma (MN) is an important cause of disability, and predictive tools for estimating the risk of recurrence are still scarce. The need for objective and cost-effective techniques addressed to this purpose is well known. In this study, we present
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::e0bc2eac41302bcd1d4eebffdf1554a1
https://www.fundanet.incliva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=16884
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2
Whole-exome sequencing, EGFR amplification and infiltration patterns in human glioblastoma
Autor: Lopez-Gines C, Munoz-Hidalgo L, San-Miguel T, Megias J, Trivino J, Calabuig S, Roldan P, Cerda-Nicolas M, Monleon D
Publikováno v: American Journal of Cancer Research
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
Consejo Superior de Investigaciones Científicas (CSIC)
Glioblastoma (GBM) is the most common malignant primary brain tumor in adults. This cancer shows rapid, highly infiltrative growth, that invades individually or in small groups the surrounding tissue. The aggressive tumor biology of GBM has devastati
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::89748969742ddfdfc370b76a66ce208b
https://www.fundanet.incliva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=16492
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3
Identification of a Novel BRCA1 Alteration in Recurrent Melanocytoma Resulting in Increased Proliferation
Autor: San-Miguel T, Navarro L, Sanchez-Sendra B, Megias J, Munoz-Hidalgo L, Santonja N, Lopez-Gines C, Cerda-Nicolas M
Publikováno v: JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
Primary meningeal melanocytomas are rare tumors of the central nervous system. Although they are considered benign neoplasms, some reports describe recurrent rates up to 45%. Little is known about their genetic and epigenetic landscape because of the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::c04d374a28d26f82f21bc8df94c05aab
https://www.fundanet.incliva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=15022
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4
Somatic copy number alterations are associated with EGFR amplification and shortened survival in patients with primary glioblastoma
Autor: Munoz-Hidalgo L, San-Miguel T, Megias J, Monleon D, Navarro L, Roldan P, Cerda-Nicolas M, Lopez-Gines C
Publikováno v: NEOPLASIA
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
Glioblastoma (GBM) is the most common malignant primary tumor of the central nervous system. With no effective therapy, the prognosis for patients is terrible poor. It is highly heterogeneous and EGFR amplification is its most frequent molecular alte
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::100292fb815692c63443b77982ad107e
https://www.fundanet.incliva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=4043
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5
Pam3CSK4, a TLR2 ligand, induces differentiation of glioblastoma stem cells and confers susceptibility to temozolomide
Autor: Megias J, Martinez A, San-Miguel T, Gil-Benso R, Munoz-Hidalgo L, Albert-Bellver D, Carratala A, Gozalbo D, Lopez-Gines C, Gil M, Cerda-Nicolas M
Publikováno v: INVESTIGATIONAL NEW DRUGS
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
Glioblastoma multiforme (GBM) is the most aggressive human brain tumor, and GBM stem cells (GSC) may be responsible for its recurrence and therapeutic resistance. Toll-like receptors (TLRs), which recognize multiple ligands (endogenous and pathogen-a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::c2d8d4b9d40626286cdaedfbc2cca34a
https://www.fundanet.incliva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=3980
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6
Identification of New Genetic Clusters in Glioblastoma Multiforme: EGFR Status and ADD3 Losses Influence Prognosis
Autor: Navarro L, San-Miguel T, Megias J, Santonja N, Calabuig S, Munoz-Hidalgo L, Roldan P, Cerda-Nicolas M, Lopez-Gines C
Publikováno v: Cells
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
Glioblastoma multiforme (GB) is one of the most aggressive tumors. Despite continuous efforts to improve its clinical management, there is still no strategy to avoid a rapid and fatal outcome. EGFR amplification is the most characteristic alteration
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::d793d99aba006876354b406b3f115fd4
https://www.fundanet.incliva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=15095
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7
The Status of EGFR Modulates the Effect of miRNA-200c on ZEB1 Expression and Cell Migration in Glioblastoma Cells
Autor: Munoz-Hidalgo L, San-Miguel T, Megias J, Serna E, Calabuig-Farinas S, Monleon D, Gil-Benso R, Cerda-Nicolas M, Lopez-Gines C
Publikováno v: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
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International Journal Of Molecular Sciences
r-FIHGUV. Repositorio Institucional de Producción Científica de la Fundación de Investigación del Hospital General de Valencia
Migration of glioblastoma cells into surrounding tissue is one of the main features that makes this tumor incurable. We evaluated whole-genome miRNA expression profiling associated with different EGFR amplification patterns in 30 cases of primary gli
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::96ac476b6d12cf9df7b5cc0300add6fa
https://www.fundanet.incliva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=15399
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8
Characterization of a new glioblastoma cell line, GB-val4, with unusual TP53 mutation
Autor: Munoz-Hidalgo L, San-Miguel T, Megias J, Gil-Benso R, Cerda-Nicolas M, Lopez-Gines C
Publikováno v: Human Cell
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
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A novel cell line derived from a human glioblastoma (GB), named GB-val4, has been established and characterized. GB-val4 cells were hyperdiploid, with many numerical and structural chromosomal rearrangements. The cell line did not show mutations in I
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::12c666ec26137f7063a33b82e9add2df
https://www.fundanet.incliva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=15801
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