Activating P2Y1 receptors improves function in arteries with repressed autophagy.

Autor: Cho JM; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT, USA.; Division of Endocrinology, Metabolism and Diabetes, Program in Molecular Medicine University of Utah School of Medicine, Salt Lake City, UT, USA., Park SK; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT, USA.; Division of Endocrinology, Metabolism and Diabetes, Program in Molecular Medicine University of Utah School of Medicine, Salt Lake City, UT, USA., Kwon OS; Department of Kinesiology, University of Connecticut, Storrs, CT, USA.; Department of Orthopedic Surgery & Center on Aging, University of Connecticut School of Medicine, Storrs, CT, USA., Taylor La Salle D; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT, USA.; Geriatric Research, Education, and Clinical Center, George E. Whalen Veterans Affairs Medical Center, Salt Lake City, UT, USA., Cerbie J; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT, USA.; Geriatric Research, Education, and Clinical Center, George E. Whalen Veterans Affairs Medical Center, Salt Lake City, UT, USA., Fermoyle CC; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT, USA.; Geriatric Research, Education, and Clinical Center, George E. Whalen Veterans Affairs Medical Center, Salt Lake City, UT, USA., Morgan D; Department of Anesthesiology, University of Utah, Salt Lake City, UT, USA., Nelson A; Geriatric Research, Education, and Clinical Center, George E. Whalen Veterans Affairs Medical Center, Salt Lake City, UT, USA., Bledsoe A; Department of Anesthesiology, University of Utah, Salt Lake City, UT, USA., Bharath LP; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT, USA.; Division of Endocrinology, Metabolism and Diabetes, Program in Molecular Medicine University of Utah School of Medicine, Salt Lake City, UT, USA., Tandar M; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT, USA., Kunapuli SP; Sol Sherry Thrombosis Research Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA., Richardson RS; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT, USA.; Geriatric Research, Education, and Clinical Center, George E. Whalen Veterans Affairs Medical Center, Salt Lake City, UT, USA.; Department of Internal Medicine, Division of Geriatrics, University of Utah, Salt Lake City, UT, USA., Anandh Babu PV; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT, USA., Mookherjee S; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT, USA.; Division of Endocrinology, Metabolism and Diabetes, Program in Molecular Medicine University of Utah School of Medicine, Salt Lake City, UT, USA., Kishore BK; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT, USA.; Nephrology Research, George E. Whalen VA Medical Center, Salt Lake City, UT, USA.; Department of Internal Medicine, Division of Nephrology, University of Utah, Salt Lake City, UT, USA., Wang F; Nephrology Research, George E. Whalen VA Medical Center, Salt Lake City, UT, USA.; Department of Internal Medicine, Division of Nephrology, University of Utah, Salt Lake City, UT, USA., Yang T; Nephrology Research, George E. Whalen VA Medical Center, Salt Lake City, UT, USA.; Department of Internal Medicine, Division of Nephrology, University of Utah, Salt Lake City, UT, USA., Boudina S; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT, USA.; Division of Endocrinology, Metabolism and Diabetes, Program in Molecular Medicine University of Utah School of Medicine, Salt Lake City, UT, USA., Trinity JD; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT, USA.; Geriatric Research, Education, and Clinical Center, George E. Whalen Veterans Affairs Medical Center, Salt Lake City, UT, USA.; Department of Internal Medicine, Division of Geriatrics, University of Utah, Salt Lake City, UT, USA., Symons JD; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT, USA.; Division of Endocrinology, Metabolism and Diabetes, Program in Molecular Medicine University of Utah School of Medicine, Salt Lake City, UT, USA.

Publikováno v: Cardiovascular research [Cardiovasc Res] 2023 Mar 17; Vol. 119 (1), pp. 252-267.

Elevated arterial shear rate increases indexes of endothelial cell autophagy and nitric oxide synthase activation in humans.

Autor: Park SK; Department of Nutrition and Integrative Physiology, University of Utah , Salt Lake City, Utah., La Salle DT; Department of Nutrition and Integrative Physiology, University of Utah , Salt Lake City, Utah.; Geriatric Research, Education, and Clinical Center, George E. Wahlen Department of Veterans Affairs Medical Center, and Department of Internal Medicine, University of Utah , Salt Lake City, Utah., Cerbie J; Department of Nutrition and Integrative Physiology, University of Utah , Salt Lake City, Utah.; Geriatric Research, Education, and Clinical Center, George E. Wahlen Department of Veterans Affairs Medical Center, and Department of Internal Medicine, University of Utah , Salt Lake City, Utah., Cho JM; Department of Nutrition and Integrative Physiology, University of Utah , Salt Lake City, Utah., Bledsoe A; Department of Anesthesiology, University of Utah , Salt Lake City, Utah., Nelson A; Geriatric Research, Education, and Clinical Center, George E. Wahlen Department of Veterans Affairs Medical Center, and Department of Internal Medicine, University of Utah , Salt Lake City, Utah., Morgan DE; Department of Anesthesiology, University of Utah , Salt Lake City, Utah., Richardson RS; Department of Nutrition and Integrative Physiology, University of Utah , Salt Lake City, Utah.; Geriatric Research, Education, and Clinical Center, George E. Wahlen Department of Veterans Affairs Medical Center, and Department of Internal Medicine, University of Utah , Salt Lake City, Utah.; Division of Geriatrics, Department of Internal Medicine, University of Utah , Salt Lake City, Utah., Shiu YT; Division of Nephrology and Hypertension, Department of Internal Medicine, University of Utah , Salt Lake City, Utah., Boudina S; Department of Nutrition and Integrative Physiology, University of Utah , Salt Lake City, Utah.; Division of Endocrinology, Metabolism, and Diabetes, and Molecular Medicine Program, University of Utah School of Medicine , Salt Lake City, Utah., Trinity JD; Department of Nutrition and Integrative Physiology, University of Utah , Salt Lake City, Utah.; Geriatric Research, Education, and Clinical Center, George E. Wahlen Department of Veterans Affairs Medical Center, and Department of Internal Medicine, University of Utah , Salt Lake City, Utah.; Division of Geriatrics, Department of Internal Medicine, University of Utah , Salt Lake City, Utah., Symons JD; Department of Nutrition and Integrative Physiology, University of Utah , Salt Lake City, Utah.; Division of Endocrinology, Metabolism, and Diabetes, and Molecular Medicine Program, University of Utah School of Medicine , Salt Lake City, Utah.

Publikováno v: American journal of physiology. Heart and circulatory physiology [Am J Physiol Heart Circ Physiol] 2019 Jan 01; Vol. 316 (1), pp. H106-H112. Date of Electronic Publication: 2018 Nov 09.

Dysfunctional and Dysregulated Nitric Oxide Synthases in Cardiovascular Disease: Mechanisms and Therapeutic Potential.

Autor: Roy, Roman¹ (AUTHOR) roman.roy@kcl.ac.uk, Wilcox, Joshua² (AUTHOR) joshua.wilcox@kcl.ac.uk, Webb, Andrew J.³ (AUTHOR) andrew.1.webb@kcl.ac.uk, O'Gallagher, Kevin^1,4 (AUTHOR) kevin.o'gallagher@kcl.ac.uk

Publikováno v: International Journal of Molecular Sciences. Oct2023, Vol. 24 Issue 20, p15200. 21p.

Cerebral blood flow dynamics: Is there more to the story at exercise onset?

Autor: Ashley, John^1,2,3 (AUTHOR), Shelley, Joe³ (AUTHOR), Song, Jiwon³ (AUTHOR), Sun, Jongjoo³ (AUTHOR), Larson, Rebecca D.⁴ (AUTHOR), Larson, Daniel J.⁵ (AUTHOR), Berkowitz, Ari⁶ (AUTHOR), Yabluchanskiy, Andriy⁷ (AUTHOR), Kellawan, J. Mikhail³ (AUTHOR) kellawan@ou.edu

Publikováno v: Physiological Reports. Jun2023, Vol. 11 Issue 11, p1-14. 14p.

Influence of Shear Stress, Inflammation and BRD4 Inhibition on Human Endothelial Cells: A Holistic Proteomic Approach.

Autor: Jarausch, Johannes^1,2 (AUTHOR), Neuenroth, Lisa¹ (AUTHOR), Andag, Reiner¹ (AUTHOR), Leha, Andreas^3,4 (AUTHOR), Fischer, Andreas^1,4,5 (AUTHOR), Asif, Abdul R.^1,4 (AUTHOR), Lenz, Christof^1,6 (AUTHOR), Eidizadeh, Abass¹ (AUTHOR) abass.eidizadeh@med.uni-goettingen.de

Publikováno v: Cells (2073-4409). Oct2022, Vol. 11 Issue 19, p3086. 16p.