Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Cera Nieto"'
Autor:
Antonio Jimeno, Rene Gonzalez, Dennis R. Roop, William Robinson, Jing H. Wang, Xiao-Jing Wang, Theresa Medina, Hilary Somerset, Aik-Choon Tan, Dexiang Gao, Randi Yeager, Bettina Miller, Karina Gomez, Cera Nieto, Phuong N. Le, Loni Perrenoud, Julie Reisinger, Tugs-Saikhan Chimed, Stephen B. Keysar, Nathaniel Alzofon, J. Jason Morton
Resistance to immunotherapy is a significant challenge, and the scarcity of human models hinders the identification of the underlying mechanisms. To address this limitation, we constructed an autologous humanized mouse (aHM) model with hematopoietic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::655a6f1c1b66b2ca94647218902d75a6
https://doi.org/10.1158/1541-7786.c.6545108.v1
https://doi.org/10.1158/1541-7786.c.6545108.v1
Autor:
Antonio Jimeno, Rene Gonzalez, Dennis R. Roop, William Robinson, Jing H. Wang, Xiao-Jing Wang, Theresa Medina, Hilary Somerset, Aik-Choon Tan, Dexiang Gao, Randi Yeager, Bettina Miller, Karina Gomez, Cera Nieto, Phuong N. Le, Loni Perrenoud, Julie Reisinger, Tugs-Saikhan Chimed, Stephen B. Keysar, Nathaniel Alzofon, J. Jason Morton
Table S1. Expanded HSPC engraftment into mouse cohorts Table S2. Human immune cell presence in HM tissues Table S3a. CUHM003 mutations present at diagnosis b. Additional CUHM003 mutations present at progression c. CUHM005 mutations present at diagnos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34c3fbcf5bdeea96081d6cb3e0e4b08c
https://doi.org/10.1158/1541-7786.22526474.v1
https://doi.org/10.1158/1541-7786.22526474.v1
Autor:
Antonio Jimeno, Xiao-Jing Wang, Hilary L. Somerset, Hongmei Zhou, Christian D. Young, Traci R. Lyons, Anit Tyagi, Farshad N. Chowdhury, Cera Nieto, Phuong N. Le, Tugs-Saikhan Chimed, Bettina Miller, J. Jason Morton, Stephen B. Keysar, FangLong Wu, Karina E. Gomez
Supplemental methods, figures, and table.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7733b2ccfea5fa2647bc8d16b3ec9517
https://doi.org/10.1158/0008-5472.22425550.v1
https://doi.org/10.1158/0008-5472.22425550.v1
Autor:
Antonio Jimeno, Tin Tin Su, David Raben, Xiao-Jing Wang, Aik-Choon Tan, Hilary L. Somerset, Gijsbertus J. Pronk, Barbara Frederick, Cera Nieto, Karina E. Gomez, Tugs-Saikhan Chimed, Julie Reisinger, J. Jason Morton, Phuong N. Le, Brian C. Jackson, Bettina Miller, Nathan Gomes, Stephen B. Keysar
SF1 is related to Fig. 1 and Fig. 2. SVC112 inhibits tumor cells growth and enhances the effects of radiation. SF2 is related to Fig. 3. SVC112 combined with radiation inhibits growth of HNSCC PDX tumors. SF3. Ribo-seq analysis of HNSCC cells treated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e2738786f1307fb8529f2039916a953
https://doi.org/10.1158/0008-5472.22424839
https://doi.org/10.1158/0008-5472.22424839
Autor:
Antonio Jimeno, Tin Tin Su, David Raben, Xiao-Jing Wang, Aik-Choon Tan, Hilary L. Somerset, Gijsbertus J. Pronk, Barbara Frederick, Cera Nieto, Karina E. Gomez, Tugs-Saikhan Chimed, Julie Reisinger, J. Jason Morton, Phuong N. Le, Brian C. Jackson, Bettina Miller, Nathan Gomes, Stephen B. Keysar
Cancer stem cells (CSC) drive growth, therapy resistance, and recurrence in head and neck squamous cell carcinoma (HNSCC). Regulation of protein translation is crucial for normal stem cells and CSCs; its inhibition could disrupt stemness properties,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e245f39ab17025ce2bac7616dc4b2b11
https://doi.org/10.1158/0008-5472.c.6511879
https://doi.org/10.1158/0008-5472.c.6511879
Autor:
Hilary Somerset, William A. Robinson, Bettina Miller, Julie Reisinger, Tugs-Saikhan Chimed, Antonio Jimeno, Phuong Le, John Morton, Rene Gonzalez, Cera Nieto, Randi Yeager, Loni Perrenoud, Xiao-Jing Wang, Stephen B. Keysar, Dennis R. Roop, Karina E. Gomez, Jing Wang, Dexiang Gao, Aik Choon Tan, Nathaniel Alzofon, Theresa Medina
Publikováno v:
Mol Cancer Res
Molecular cancer research : MCR, vol 19, iss 2
Molecular cancer research : MCR, vol 19, iss 2
Resistance to immunotherapy is a significant challenge, and the scarcity of human models hinders the identification of the underlying mechanisms. To address this limitation, we constructed an autologous humanized mouse (aHM) model with hematopoietic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d2883a4191178afbbc43532edf2c00f
https://doi.org/10.1158/1541-7786.mcr-20-0686
https://doi.org/10.1158/1541-7786.mcr-20-0686
Autor:
Brian C. Jackson, John Morton, Hilary Somerset, Nathan Gomes, Aik Choon Tan, Barbara Frederick, Julie Reisinger, Phuong Le, Xiao-Jing Wang, David Raben, Stephen B. Keysar, Tin Tin Su, Gijsbertus J. Pronk, Cera Nieto, Karina E. Gomez, Bettina Miller, Tugs-Saikhan Chimed, Antonio Jimeno
Publikováno v:
Cancer research, vol 80, iss 5
Cancer Res
Cancer Res
Cancer stem cells (CSC) drive growth, therapy resistance, and recurrence in head and neck squamous cell carcinoma (HNSCC). Regulation of protein translation is crucial for normal stem cells and CSCs; its inhibition could disrupt stemness properties,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c49c07fb49c525adbd924d98ccdec88
https://doi.org/10.1158/0008-5472.can-19-3232
https://doi.org/10.1158/0008-5472.can-19-3232
Autor:
Etienne Danis, Elizabeth E. Smith, Claire M. Gillette, Lindsey Ulkus Rodrigues, Lina Romero, Kathleen C. Torkko, Lauren K. Jillson, Donna M. Peehl, Leah Rider, Scott D. Cramer, Cera Nieto, Anis Karimpour-Fard, James C. Costello, Rosalie Nolley, M. Scott Lucia
Publikováno v:
Mol Cancer Res
Prostate cancer genomic subtypes that stratify aggressive disease and inform treatment decisions at the primary stage are currently limited. Previously, we functionally validated an aggressive subtype present in 15% of prostate cancer characterized b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bee2b164330a610756cc40d1e1e10475
https://europepmc.org/articles/PMC8254790/
https://europepmc.org/articles/PMC8254790/
Autor:
Hilary Somerset, Phuong Le, Farshad N. Chowdhury, Tugs-Saikhan Chimed, Antonio Jimeno, Karina E. Gomez, Bettina Miller, Carissa M. Thomas, Julie Reisinger, Stephen B. Keysar, Cera Nieto, Xiao-Jing Wang, John Morton
Publikováno v:
Oral Oncol
Objectives To describe differences in cancer stem cell (CSC) presence and behavior associated with their intratumor compartment of origin using a patient-derived xenograft (PDX) model of oral cavity squamous cell carcinoma (OCSCC). Materials and meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2bf719a2a413e42b25d62c43e747a28
https://pubmed.ncbi.nlm.nih.gov/31586893
https://pubmed.ncbi.nlm.nih.gov/31586893
Autor:
Bettina Miller, Julie Reisinger, Phuong Le, Cera Nieto, Brian C. Jackson, Hilary Somerset, Stephen B. Keysar, Karina E. Gomez, John Morton, Tugs-Saikhan Chimed, Antonio Jimeno, Xiao-Jing Wang, Justin R. Eagles
Publikováno v:
Molecular carcinogenesis, vol 58, iss 3
Wnt pathway activation maintains the cancer stem cell (CSC) phenotype and promotes tumor progression, making it an attractive target for anti-cancer therapy. Wnt signaling at the tumor and tumor microenvironment (TME) front have not been investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1b02cda2af4cda6bf6096aefa64787b
https://escholarship.org/uc/item/4mk0n6nc
https://escholarship.org/uc/item/4mk0n6nc