Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Cephalostatin 1"'
Publikováno v:
Heliyon, Vol 6, Iss 1, Pp e03025- (2020)
Herewith, we report on a method that allows to simultaneously protect both the ∆14,15 bond and the carbonyl group of the symmetrical bis-steroidal diketone 2. We found that environmentally friendly and gas-free chlorination is ideally suited to ach
Externí odkaz:
https://doaj.org/article/4836cf329b9b4141badc1801535c2e99
Publikováno v:
Heliyon 6 (2020), Nr. 1
Heliyon
Heliyon, Vol 6, Iss 1, Pp e03025-(2020)
Heliyon
Heliyon, Vol 6, Iss 1, Pp e03025-(2020)
Herewith, we report on a method that allows to simultaneously protect both the ∆14,15 bond and the carbonyl group of the symmetrical bis-steroidal diketone 2. We found that environmentally friendly and gas-free chlorination is ideally suited to ach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d577daf5ec6c606f81013fade098f2ac
https://www.repo.uni-hannover.de/handle/123456789/10949
https://www.repo.uni-hannover.de/handle/123456789/10949
Autor:
Rayala Naveen Kumar, Seongmin Lee
Publikováno v:
Steroids. 118:68-75
An efficient synthesis of the 23-deoxy-25-epi north unit of cephalostatin 1 has been achieved in 17 steps via reductive and oxidative functionalizations of hecogenin acetate with an overall yield of 3.8%. This synthesis features transetherification-m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::256046aee494136da40d57ce50d89bb4
https://doi.org/10.1016/j.steroids.2016.12.012
https://doi.org/10.1016/j.steroids.2016.12.012
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
Mansour Nawasreh
Publikováno v:
Pure and Applied Chemistry. 83:699-707
The highly tumor inhibitory cephalostatins (e.g., cephalostatin 1), a marine natural product isolated from Cephalodiscus gilcristi, have attracted us to synthesize biologically active analogues. The goal of this study is to shed more light on selecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42fca120759c69d1a58a1f03d251327e
https://doi.org/10.1351/pac-con-10-08-15
https://doi.org/10.1351/pac-con-10-08-15
Autor:
Ricardo C. Del Rosario, Eduardo R. Mendoza, Angelika M. Vollmar, Eva M. Rodriguez, Anita Rudy
Publikováno v:
Natural Computing. 10:993-1015
Understanding the mechanisms involved in apoptosis has been an area of extensive study due to its critical role in the development and homeostasis of multi-cellular organisms. Our special interest lies in understanding the apoptosis of tumor cells wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5d2639b9403b9f1315f4431f00127ec
https://doi.org/10.1007/s11047-009-9153-9
https://doi.org/10.1007/s11047-009-9153-9
Publikováno v:
Organic Letters. 11:5-8
The C14,15-dihydro-C22,25-epi north unit of cephalostatin 1 has been synthesized in 11 operations from commercially available hecogenin acetate via multiple reductions and oxidations. The key transformations include (i) Cr(VI)-catalyzed E-ring openin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77f9b68536ad24c3719178839db15cd2
https://doi.org/10.1021/ol802122p
https://doi.org/10.1021/ol802122p