The centriolar satellite protein Cfap53 facilitates formation of the zygotic microtubule organizing center in the zebrafish embryo

Autor: Willekers, Sven, Tessadori, Federico, van der Vaart, Babet, Henning, Heiko H., Stucchi, Riccardo, Altelaar, Maarten, Roelen, Bernard A.J., Akhmanova, Anna, Bakkers, Jeroen, Sub Cell Biology, Voortplanting paard, Afd Biomol.Mass Spect. and Proteomics, Anatomie en fysiologie, Celbiologie, Al het onderzoek van de faculteit Diergeneeskunde, CS_Cancer

Publikováno v: Development (Cambridge, England), 149(16), 1. Company of Biologists Ltd
Development (Cambridge), 149(16). Company of Biologists Ltd

In embryos of most animal species, the zygotic centrosome is assembled by the centriole derived from the sperm cell and pericentriolar proteins present in the oocyte. This zygotic centrosome acts as a microtubule organizing center (MTOC) to assemble

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9201a33b12009a9e3c67971c904e84a8
https://doi.org/10.1242/dev.198762

The Tubulin Code in Mitosis and Cancer

Autor: Helder Maiato, Danilo Lopes

Publikováno v: Cells
Cells, Vol 9, Iss 2356, p 2356 (2020)

The "tubulin code" combines different a/ß-tubulin isotypes with several post-translational modifications (PTMs) to generate microtubule diversity in cells. During cell division, specific microtubule populations in the mitotic spindle are differentia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02a10aacc345646ff952f29ff23861b1
https://pubmed.ncbi.nlm.nih.gov/33114575

A Cell/Cilia Cycle Biosensor for Single-Cell Kinetics Reveals Persistence of Cilia after G1/S Transition Is a General Property in Cells and Mice

Autor: Ford, Matthew J., Yeyati, Patricia L., Mali, Girish R., Keighren, Margaret A., Waddell, Scott H., Mjoseng, Heidi K., Douglas, Adam T., Hall, Emma A., Sakaue-Sawano, Asako, Miyawaki, Atsushi, Meehan, Richard R., Boulter, Luke, Jackson, Ian J., Mill, Pleasantine, Mort, Richard L.

Publikováno v: Ford, M J, Yeyati, P, Mali, G, Keighren, M A, Waddell, S, Mjoseng, H K, Douglas, A T, Hall, E A, Sakaue-Sawano, A, Miyawaki, A, Meehan, R R, Boulter, L, Jackson, I J, Mill, P & Mort, R L 2018, ' A Cell/Cilia Cycle Biosensor for Single-Cell Kinetics Reveals Persistence of Cilia after G1/S Transition Is a General Property in Cells and Mice ', Developmental Cell, vol. 47, no. 4, pp. 509-523.e5 . https://doi.org/10.1016/j.devcel.2018.10.027
Ford, M J, Yeyati, P L, Mali, G R, Keighren, M A, Waddell, S H, Mjoseng, H K, Douglas, A T, Hall, E A, Sakaue-Sawano, A, Miyawaki, A, Meehan, R R, Boulter, L, Jackson, I J, Mill, P & Mort, R L 2018, ' A Cell/Cilia Cycle Biosensor for Single-Cell Kinetics Reveals Persistence of Cilia after G1/S Transition Is a General Property in Cells and Mice ', Developmental Cell, vol. 47, no. 4, E5, pp. 509-523 . https://doi.org/10.1016/j.devcel.2018.10.027
Developmental Cell

Summary The cilia and cell cycles are inextricably linked. Centrioles in the basal body of cilia nucleate the ciliary axoneme and sequester pericentriolar matrix (PCM) at the centrosome to organize the mitotic spindle. Cilia themselves respond to gro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::dbaa96089d1d75f1da6c917fa139efa3
https://www.pure.ed.ac.uk/ws/files/76966693/A_cell_cilia_cycle_biosensor_for_single_cell_kinetics_reveals_persistence_of_cilia_after_the_G1_S_transition_is_a_general_property_in_cells_and_mice.pdf

Analysis of centrosome and DNA damage response in PLK4 associated Seckel syndrome

Autor: Dinçer T, Yorgancıoğlu-Budak G, Ölmez A, Er İ, Dodurga Y, Özdemir ÖM, Toraman B, Yıldırım A, Sabir N, Akarsu NA, Semerci CN, Kalay E

Microcephalic primordial dwarfism (MPD) is a group of autosomal recessive inherited single-gene disorders with intrauterine and postnatal global growth failure. Seckel syndrome is the most common form of the MPD. Ten genes are known with Seckel syndr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3566::b011224b180a5134be50ae4c6cdea8fb

Zika Virus Disrupts Phospho-TBK1 Localization and Mitosis in Human Neuroepithelial Stem Cells and Radial Glia

Autor: Tamas L. Horvath, Maria Teresa Dell’Anno, Xiao-Bing Gao, Naoki Nakagawa, Anze Testen, Yalan Zhang, Tianliuyun Gao, Mihovil Pletikos, Candace Bichsel, Nenad Sestan, Mingfeng Li, Sirisha Pochareddy, Brett D. Lindenbach, Leonard K. Kaczmarek, Zhen Li, Wenqi Han, Forrest O. Gulden, Fuchen Liu, André M. M. Sousa, Stephen M. Strittmatter, Andrew T.N. Tebbenkamp, Marco Onorati, Steven Lisgo, Jernej Mlakar, Marie Flamand, Mara Popović, Eva S. Anton, Luis Varela, Klara Szigeti-Buck, Ying Zhu

Publikováno v: Cell Reports
Cell Reports, Elsevier Inc, 2016, 16 (10), pp.2576-2592. ⟨10.1016/j.celrep.2016.08.038⟩
Cell Reports, 2016, 16 (10), pp.2576-2592. ⟨10.1016/j.celrep.2016.08.038⟩
Cell Reports, Vol 16, Iss 10, Pp 2576-2592 (2016)

SummaryThe mechanisms underlying Zika virus (ZIKV)-related microcephaly and other neurodevelopment defects remain poorly understood. Here, we describe the derivation and characterization, including single-cell RNA-seq, of neocortical and spinal cord

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8842a91c108e53c206bfa4ca694b4d28
https://hal-pasteur.archives-ouvertes.fr/pasteur-01739212