Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Centromere localization"'
Autor:
Jude W. Grosser, Wen-Wu Guo, Xiao-Meng Wu, Kai-Dong Xie, Qiang-Ming Xia, Zhao-Ping Yin, Chunli Chen, Lu-Ke Miao
Publikováno v:
Plant Cell Reports. 39:1609-1622
The physical locations of citrus centromere are revealed by combining genetic and immunological assays for the first time and nine citrus centromere-specific markers for cytogenetics are mined. Centromere localization is challenging, because highly r
Publikováno v:
J Cell Sci
Centromere structure and function are defined by the epigenetic modification of histones at centromeric and pericentromeric chromatin. The constitutive heterochromatin found at pericentromeric regions is highly enriched for H3K9me3 and H4K20me3. Alth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38642f6d06da95ed45e4b0825aefaaa2
https://europepmc.org/articles/PMC8353524/
https://europepmc.org/articles/PMC8353524/
Publikováno v:
The Journal of Cell Biology
Kinetoplastids are evolutionarily divergent eukaryotes that have an unconventional set of kinetochore proteins. Marcianò et al. show that KKT2 and KKT3 play important roles in kinetochore assembly in Trypanosoma brucei. Centromere localization of th
Autor:
Jun Huang, Lu Yan, Long Zhang, Weiguo Lu, Junfen Xu, Xueying Yuan, Linghui Zeng, Qinfu Chen, Bing Yang, Miao Zhang, Linli Zhou, Xuan Pan, Tatsuo Fukagawa, Fangwei Wang, Haiyan Yan
Publikováno v:
Cell Reports, Vol 36, Iss 12, Pp 109740-(2021)
Summary: Bub1 is required for the kinetochore/centromere localization of two essential mitotic kinases Plk1 and Aurora B. Surprisingly, stable depletion of Bub1 by ∼95% in human cells marginally affects whole chromosome segregation fidelity. We sho
Autor:
Poornima Yedavalli, Theodor Marsoner, Katrin Schmitzer, Chiara Masnovo, Christopher J. Campbell
Chromosome biorientation is established by the four-member chromosomal passenger complex (CPC) through phosphorylation of incorrect kinetochore-microtubule attachments. During chromosome alignment, the CPC localizes to the inner centromere, the inner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7da43349541efc1563015409e2717ef
https://doi.org/10.1101/2020.09.10.288878
https://doi.org/10.1101/2020.09.10.288878
Akademický článek
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Autor:
Belinda S. Pinto, Terry L. Orr-Weaver
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Meiosis is the specialized cell division that generates haploid sperm and eggs. Proper segregation of chromosomes in meiosis is required to prevent pregnancy loss and birth defects. This requires that the replicated copies of each chromo
Publikováno v:
Genesgenetic systems. 94(4)
Gene-centromere (G-C) mapping provides insight into vertebrate genome composition, structure and evolution. Although medaka fish are important experimental animals, no genome-wide G-C map of medaka has been constructed. In this study, we used 112 int
Autor:
Aaron F. Straight, Bradley T. French
Publikováno v:
The EMBO Journal. 38
Chromosome segregation requires the centromere, the site on chromosomes where kinetochores assemble in mitosis to attach chromosomes to the mitotic spindle. Centromere identity is defined epigenetically by the presence of nucleosomes containing the h
Publikováno v:
Dev Cell
CENP-A is a centromere-specific histone H3 variant that epigenetically determines centromere identity, but how CENP-A is deposited at the centromere remains obscure. We previously reported that CENP-A K124 ubiquitylation, mediated by the CUL4A-RBX1-C