Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Centre for Infectious Disease Research"'
Autor:
John Kenneth, Vasista Adiga, M. Juliana McElrath, Wesley Bonam, Christina Johnson, Stephen C. De Rosa, George D'Souza, Greg Finak, Asma Ahmed, Annapurna Vyakarnam, Raphael Gottardo, Srabanti Rakshit, Tom H. M. Ottenhoff, Kees L. M. C. Franken, Kenneth Stuart, Pravat Nalini Sahoo, Bharath K. Sundararaj
Publikováno v:
Rakshit, S, Ahmed, A, Adiga, V, Sundararaj, B K, Sahoo, P N, Kenneth, J, D'Souza, G, Bonam, W, Johnson, C, Franken, K L, Ottenhoff, T H, Finak, G, Gottardo, R, Stuart, K D, De Rosa, S C, McElrath, M J & Vyakarnam, A 2019, ' BCG revaccination boosts adaptive polyfunctional Th1/Th17 and innate effectors in IGRA+ and IGRA-Indian adults ', JCI Insight, vol. 4, no. 24, 135946506 . https://doi.org/10.1172/jci.insight.130540
JCI Insight, 4(24). AMER SOC CLINICAL INVESTIGATION INC
JCI Insight, 4(24). AMER SOC CLINICAL INVESTIGATION INC
BACKGROUND: Bacille Calmette-Guérin (BCG) vaccine is protective against Tuberculosis (TB) in children, but its efficacy wanes with age. Consequently, determining if BCG revaccination augments anti-TB immunity in young adults in TB endemic regions is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d43b4de0b76765d5b4ad58467ce08c2
https://hdl.handle.net/1887/121988
https://hdl.handle.net/1887/121988
Autor:
Aaron Briley, Adil Mohamed, Debjani Saha, Clara Si, Brad R. Rosenberg, Adolfo García-Sastre, Guojun Wang, Sarah Ballentine, Hong M. Moulton, Shashank Tripathi, Uwe Schaefer, Leon Louis Seifert, Ana M. Valero-Jimenez, Mohammad Sadic, Maren de Vries, Meike Dittmann
Publikováno v:
PLoS Pathogens, Vol 15, Iss 11, p e1007634 (2019)
PLoS Pathogens
PLoS Pathogens
Induction of vast transcriptional programs is a central event of innate host responses to viral infections. Here we report a transcriptional program with potent antiviral activity, driven by E74-like ETS transcription factor 1 (ELF1). Using microscop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dc46706a88f6d20514cbb092d9d0aae
Autor:
Sreenath Balakrishnan, Narendra M. Dixit, Harsha Raheja, Pratik Dave, Biju George, Saumitra Das, Divya Khandige Sharma
Publikováno v:
RNA Biol
Coxsackievirus B3 is an enterovirus, with positive-sense single-stranded RNA genome containing `Internal Ribosome Entry Site' (IRES) in the 5MODIFIER LETTER PRIMEUTR. Once sufficient viral proteins are synthesized in the cell from the input RNA, vira
Publikováno v:
J Biol Chem
During enteroviral infections, the canonical translation factor eukaryotic translation initiation factor 4 ? I (eIF4GI) is cleaved by viral protease 2A. The resulting C-terminal fragment is recruited by the viral internal ribosome entry site (IRES) f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::654b713abb310b575470e4dd27cfa1f5
https://europepmc.org/articles/PMC6802510/
https://europepmc.org/articles/PMC6802510/
Publikováno v:
IndraStra Global.
Bacterial cold shock proteins (CSPs) function as RNA chaperones. To assess CSP's roles in the intracellular human pathogen Salmonella Typhimurium, we analyzed their expression in varied stress conditions. We found that cold shock protein E (cspE or S
Autor:
Dipankar Nandi, Shamik Majumdar, Vasista Adiga, Supriya Rajendra Rananaware, Abinaya Raghavan
Publikováno v:
Immunology
The development of immunocompetent T cells entails a complex pathway of differentiation in the thymus. Thymic atrophy occurs with ageing and during conditions such as malnutrition, infections and cancer chemotherapy. The comparative changes in thymic
Autor:
Arunachalam Ramaiah, Soumya Nayak, Srabanti Rakshit, Abigail L. Manson, Thomas Abeel, Sivakumar Shanmugam, Pravat Nalini Sahoo, Anto Jesuraj Uday Kumar John, Jagadish Chandrabose Sundaramurthi, Sujatha Narayanan, George D'Souza, Paul von Hoegen, Tom H. M. Ottenhoff, Soumya Swaminathan, Ashlee M. Earl, Annapurna Vyakarnam
Publikováno v:
Frontiers in immunology, vol 10, iss FEB
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology
Frontiers in Immunology, 10
Ramaiah, A, Nayak, S, Rakshit, S, Manson, A L, Abeel, T, Shanmugam, S, Sahoo, P N, John, A J U K, Sundaramurthi, J C, Narayanan, S, D'souza, G, Von Hoegen, P, Ottenhoff, T H M, Swaminathan, S, Earl, A M & Vyakarnam, A 2019, ' Evidence for Highly Variable, Region-Specific Patterns of T-Cell Epitope Mutations Accumulating in Mycobacterium tuberculosis Strains ', Frontiers in Immunology, vol. 10, no. 0, 195 . https://doi.org/10.3389/fimmu.2019.00195
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology
Frontiers in Immunology, 10
Ramaiah, A, Nayak, S, Rakshit, S, Manson, A L, Abeel, T, Shanmugam, S, Sahoo, P N, John, A J U K, Sundaramurthi, J C, Narayanan, S, D'souza, G, Von Hoegen, P, Ottenhoff, T H M, Swaminathan, S, Earl, A M & Vyakarnam, A 2019, ' Evidence for Highly Variable, Region-Specific Patterns of T-Cell Epitope Mutations Accumulating in Mycobacterium tuberculosis Strains ', Frontiers in Immunology, vol. 10, no. 0, 195 . https://doi.org/10.3389/fimmu.2019.00195
Vaccines that confer protection through induction of adaptive T-cell immunity rely on understanding T-cell epitope (TCE) evolution induced by immune escape. This is poorly understood in tuberculosis (TB), an ancient, chronic disease, where CD4 T-cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28e84d4a814784e2a5a82d25c22077aa
https://escholarship.org/uc/item/4jw8w6vh
https://escholarship.org/uc/item/4jw8w6vh
Autor:
Amit Singh, Abhilash Mohan, Chandrani Thakur, Kushi Anand, Jyothi Padiadpu, Priyanka Baloni, Nagasuma Chandra, MohamedHusen Munshi
Publikováno v:
ACS Infectious Diseases. 2:592-607
The global mechanisms and associated molecular alterations that occur in drug-resistant mycobacteria are poorly understood. To address this, we obtain genomics data and then construct a genome-scale response network in isoniazid-resistant Mycobacteri
Publikováno v:
FEMS microbiology letters. 365(22)
The factors contributing to antibiotic resistance in bacteria are an important area of study. Sodium salicylate (NaSal), a non-steroidal anti-inflammatory drug (NSAID), increases antibiotic resistance by inducing the expression of MarA, a transcripti
Autor:
Shikha Yadav, Semanti Ray, Dipankar Nandi, Sanmoy Pathak, Shamik Majumdar, Vasista Adiga, Mohsen Sarikhani, Bhagawat Chandrasekar, Nagalingam R. Sundaresan
Publikováno v:
IndraStra Global.
Sepsis, a leading cause of death in intensive care units, is primarily caused due to an exaggerated immune response. The hyperactive inflammatory response mediated by immune cells against infectious organisms and their toxins results in host cell dea