Zobrazeno 1 - 10 of 13 pro vyhledávání: '"Central Nervous System Neoplasms/drug therapy"'
1
Akademický článek
A Rare Case of Spontaneous Remission and Relapse of a Primary Central Nervous System Lymphoma
Autor: Rui Ramos, João Soares Fernandes, Marta Almeida, Rui Almeida
Publikováno v: Acta Médica Portuguesa, Vol 31, Iss 12, Pp 777-783 (2018)
Primary central nervous system lymphoma remission after steroid treatment is a well-known phenomenon, but remission without any type of treatment is extremely rare. We present a rare case of spontaneous remission of a diffuse large B-cell lymphoma of
Externí odkaz: https://doaj.org/article/4c09457e5ec5479fa1b2fb1e211c8f57
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2
CNS prophylaxis for diffuse large B-cell lymphoma
Autor: Toby A Eyre, Kerry J Savage, Chan Y Cheah, Tarec C El-Galaly, Katharine L Lewis, Pamela McKay, Matthew R Wilson, Andrew M Evens, Sabela Bobillo, Diego Villa, Matthew J Maurer, Kate Cwynarski, Andrés J M Ferreri
Publikováno v: Eyre, T A, Savage, K J, Cheah, C Y, El-Galaly, T C, Lewis, K L, McKay, P, Wilson, M R, Evens, A M, Bobillo, S, Villa, D, Maurer, M J, Cwynarski, K & Ferreri, A J M 2022, ' CNS prophylaxis for diffuse large B-cell lymphoma ', The Lancet Oncology, vol. 23, no. 9, pp. e416-e426 . https://doi.org/10.1016/S1470-2045(22)00371-0
CNS relapse in the brain parenchyma, eyes, or leptomeninges is an uncommon but devastating complication of diffuse large B-cell lymphoma. CNS prophylaxis strategies, typically involving intrathecal or high-dose antimetabolites, have been developed in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aa3c1e3efbbf620a467525e4e71a0a3
https://pubmed.ncbi.nlm.nih.gov/36055310
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3
Timing of high-dose methotrexate CNS prophylaxis in DLBCL: an analysis of toxicity and impact on R-CHOP delivery
Autor: Thomas Creasey, Nimish Shah, Jeremy Schofield, Kate Cwynarski, Matthew R. Wilson, Jeffery Smith, Toby A. Eyre, Cheuk Kie Cheung, Fiona Miall, Kim Linton, Katrina Parsons, Christopher P. Fox, Gavin Preston, Pamela McKay, Matthew J. Ahearne, Matthew A. Timmins, Almurtadha Mula Kh, Jahanzaib Khwaja, Nicolas Martinez-Calle, Johnathon Elliot
Publikováno v: Blood Adv
Wilson, M R, Eyre, T A, Martinez-Calle, N, Ahearne, M, Parsons, K E, Preston, G, Khwaja, J, Schofield, J, Elliot, J, Kh, A M, Shah, N, Cheung, C K, Timmins, M A, Creasey, T, Linton, K, Smith, J, Fox, C P, Miall, F, Cwynarski, K & McKay, P 2020, ' Timing of high-dose methotrexate CNS prophylaxis in DLBCL : An analysis of toxicity and impact on R-CHOP delivery ', Blood Advances, vol. 4, no. 15, pp. 3586-3593 . https://doi.org/10.1182/bloodadvances.2020002421
High-dose methotrexate (HD-MTX) is increasingly used as prophylaxis for patients with diffuse large B-cell lymphoma (DLBCL) at high risk of central nervous system (CNS) relapse. However, there is limited evidence to guide whether to intercalate HD-MT
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6a2409dbd0bd720cf92cdf284785ac8
https://pubmed.ncbi.nlm.nih.gov/32761231
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4
A Rare Case of Spontaneous Remission and Relapse of a Primary Central Nervous System Lymphoma
Autor: João Fernandes, Rui Ramos, Marta Almeida, Rui M. Almeida
Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Acta Médica Portuguesa, Vol 31, Iss 12, Pp 777-783 (2018)
Primary central nervous system lymphoma remission after steroid treatment is a well-known phenomenon, but remission without any type of treatment is extremely rare. We present a rare case of spontaneous remission of a diffuse large B-cell lymphoma of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdf4557e3a2e7f0d1d01dd553581e0ba
https://doi.org/10.20344/amp.10198
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5
Alectinib versus Crizotinib in Untreated ALK-Positive Non–Small-Cell Lung Cancer
Autor: Rafael Rosell, Alice T. Shaw, Ali Zeaiter, Shirish M. Gadgeel, Emmanuel Mitry, Bogdana Balas, Jin S. Ahn, Maurice Perol, Johannes Noe, Sai-Hong Ignatius Ou, Peter N. Morcos, D. Ross Camidge, Solange Peters, Tony Mok, Dong Wan Kim, Rafal Dziadziuszko, Sophie Golding
Publikováno v: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
The New England journal of medicine, vol. 377, no. 9, pp. 829-838
Alectinib, a highly selective inhibitor of anaplastic lymphoma kinase (ALK), has shown systemic and central nervous system (CNS) efficacy in the treatment of ALK-positive non-small-cell lung cancer (NSCLC). We investigated alectinib as compared with
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18d35d488c552e94e96cbf18b7922921
https://doi.org/10.1056/nejmoa1704795
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6
Treatment strategies, outcomes and prognostic factors in 291 patients with secondary CNS involvement by diffuse large B-cell lymphoma
Autor: Brian K. Link, Eldad J. Dann, Roopesh Kansara, Maja Bech Juul, Gita Thanarajasingam, Adir Shaulov, Umar Farooq, Michael Roost Clausen, Daniel J. Smith, Andrés J.M. Ferreri, Diego Villa, Joseph M. Connors, Michael Gilbertson, Chan Yoon Cheah, Tarec Christoffer El-Galaly, Thomas Stauffer Larsen, Carrie A. Thompson, Martin Hutchings, Inger Lise Gade, John F. Seymour, Neta Goldschmidt, Teresa Calimeri, Kerry J. Savage, Jakob Werner Hansen, Grzegorz S. Nowakowski, Stephen Opat, Mette Dahl Bendtsen, Laurie H. Sehn, Staffan Holmberg, N. George Mikhaeel, Matthew J. Maurer, C. Cecchetti, Tsofia Inbar, Sabrina Cordua
Publikováno v: El-Galaly, T C, Cheah, C Y, Bendtsen, M D, Nowakowski, G S, Kansara, R, Savage, K J, Connors, J M, Sehn, L H, Goldschmidt, N, Shaulov, A, Farooq, U, Link, B K, Ferreri, A J M, Calimeri, T, Cecchetti, C, Dann, E J, Thompson, C A, Inbar, T, Maurer, M J, Gade, I L, Juul, M B, Hansen, J W, Holmberg, S, Larsen, T S, Cordua, S, Mikhaeel, N G, Hutchings, M, Seymour, J F, Clausen, M R, Smith, D, Opat, S, Gilbertson, M, Thanarajasingam, G & Villa, D 2018, ' Treatment strategies, outcomes and prognostic factors in 291 patients with secondary CNS involvement by diffuse large B-cell lymphoma ', European Journal of Cancer, vol. 93, pp. 57-68 . https://doi.org/10.1016/j.ejca.2018.01.073
PURPOSE: Secondary CNS involvement (SCNS) is a profoundly adverse complication of diffuse large B-cell lymphoma. Evidence from older series indicated a median overall survival (OS) < 6 months; however, data from the immunochemotherapy era are limited
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2b4286ba19f96fcf65520e603491c18
https://pure.au.dk/portal/da/publications/treatment-strategies-outcomes-and-prognostic-factors-in-291-patients-with-secondary-cns-involvement-by-diffuse-large-bcell-lymphoma(f3dacb05-0ad4-4eb4-86b5-eff16e7f2727).html
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7
Akademický článek
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8
The role of cytotoxic drugs in the treatment of central nervous system gliomas
Autor: Bart Neyns, Haeseleer, Miguel D., Anne Rogiers, Joy Van de Cauter, Cristo Chaskis, Alex Michotte, Herwig Strik
Publikováno v: Vrije Universiteit Brussel
Acta neurologica Belgica
Gliomas are the most frequent subtype of primary brain tumors. They are lethal tumors, characterized by diffuse infiltration of the brain and a high resistance to conventional cancer therapies. Following maximal neurosurgical resection, bound to the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::dfcf086cf401a92eff3426f0bbe092b8
https://hdl.handle.net/20.500.14017/ca361c3d-dac3-4bba-ad9e-c5bebbc4c81b
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