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Publikováno v:
GLIA, 67(8), 1417. John Wiley and Sons Inc.
Glia
GLIA, 33, 12941-12959. John Wiley and Sons Inc.
Glia
GLIA, 33, 12941-12959. John Wiley and Sons Inc.
Gliomas are a heterogenous group of malignant primary brain tumors that arise from glia cells or their progenitors and rely on accurate diagnosis for prognosis and treatment strategies. Although recent developments in the molecular biology of glioma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2d8fa43ec25b068405b10fd195da127
https://hdl.handle.net/20.500.11755/6996e14f-b62d-4cfe-9d02-95923849733c
https://hdl.handle.net/20.500.11755/6996e14f-b62d-4cfe-9d02-95923849733c
Autor:
Till Milde, Matija Snuderl, Martin Bendszus, Ralf Ketter, Catherine Keohane, Marco Prinz, Katja von Hoff, Aristotelis Tsirigos, Hildegard Dohmen, Manfred Westphal, Ute Pohl, Gabriele Schackert, Christian Koelsche, Eleonora Aronica, Bernhard Radlwimmer, Bjarne Winther Kristensen, Martin Hasselblatt, David T.W. Jones, Christian Mawrin, Dominik Sturm, Patricia Kohlhof, Peter Lichter, Annekathrin Kratz, Anne K. Braczynski, Helmut Mühleisen, Wolf Mueller, Wolfgang Brück, Stephan Frank, Andreas Unterberg, Michael Weller, Matthias A. Karajannis, Astrid Gnekow, Lukas Chavez, Andreas E. Kulozik, Christoph Geisenberger, Christine Haberler, Ori Staszewski, Amar Gajjar, Stephanie Rozsnoki, Mélanie Pagès, Olaf Witt, Paul A. Northcott, Matt Lechner, Thomas S. Jacques, Martina Deckert, Axel Benner, Jordan R. Hansford, Ingmar Blümcke, Marina Ryzhova, Gudrun Fleischhack, Jonathan Serrano, Jens Schittenhelm, Martin Sill, Sebastian Brandner, Stephan Tippelt, Dietmar R. Lohmann, Hermann L. Müller, Petra Temming, Nils W. Engel, Khalida Wani, Pablo Hernáiz Driever, Christel Herold-Mende, David W. Ellison, Arie Perry, Michael C. Frühwald, Stefan M. Pfister, Christof M. Kramm, Stefanie Brehmer, Daniel Hänggi, Jane Cryan, Torsten Pietsch, Wolfram Scheurlen, Marcel Seiz-Rosenhagen, Volkmar Hans, Adriana Olar, Werner Paulus, Chris Jones, Annie Huang, Patrick N. Harter, Felice Giangaspero, Marcel Kool, Kenneth Aldape, Marco Gessi, Silvia Hofer, Fausto J. Rodriguez, Anne Jouvet, Roland Coras, Annika K. Wefers, Leonille Schweizer, Vincent Peter Collins, Beatriz Lopes, Rolf Bjerkvig, Matthias Schick, Michel Mittelbronn, Andrey Korshunov, Johannes Schramm, Marc Zapatka, Annett Hölsken, Michael Platten, Kerstin Lindenberg, Jürgen Debus, Christian Hartmann, Ekkehard Hewer, Pascale Varlet, Melanie Bewerunge-Hudler, Till Acker, Matthias Preusser, Elisabeth J. Rushing, Michael A. Farrell, Kristian W. Pajtler, Nada Jabado, Kasthuri Kannan, Wolfgang Wick, David E. Reuss, Rolf Buslei, Nicholas G. Gottardo, Giles W. Robinson, Stefan Rutkowski, Jürgen Hench, Andreas von Deimling, Ulrich Schüller, Zane Jaunmuktane, Pieter Wesseling, Hendrik Witt, Albert J. Becker, Frank L. Heppner, Roger Fischer, Ziad Khatib, Guido Reifenberger, Arend Koch, Gabriele Calaminus, Karl H. Plate, Volker Hovestadt, Michael D. Taylor, Camelia-Maria Monoranu, Damian Stichel, Felix Sahm, Kristin Huang, David Capper, Florian Selt, Daniel Schrimpf, Rudi Beschorner, Boyan K. Garvalov
Publikováno v:
Nature, 555(7697), 469-474. Nature Publishing Group
Nature, 555(7697), 469. Nature Publishing Group
Capper, D, Jones, D T W, Sill, M, Hovestadt, V, Schrimpf, D, Sturm, D, Koelsche, C, Sahm, F, Chavez, L, Reuss, D E, Kratz, A, Wefers, A K, Huang, K, Pajtler, K W, Schweizer, L, Stichel, D, Olar, A, Engel, N W, Lindenberg, K, Harter, P N, Braczynski, A K, Plate, K H, Dohmen, H, Garvalov, B K, Coras, R, Hölsken, A, Hewer, E, Bewerunge-Hudler, M, Schick, M, Fischer, R, Beschorner, R, Schittenhelm, J, Staszewski, O, Wani, K, Varlet, P, Pages, M, Temming, P, Lohmann, D, Selt, F, Witt, H, Milde, T, Witt, O, Aronica, E, Giangaspero, F, Rushing, E, Scheurlen, W, Geisenberger, C, Rodriguez, F J, Becker, A, Preusser, M, Haberler, C, Bjerkvig, R, Cryan, J, Farrell, M, Deckert, M, Hench, J R, Frank, S, Serrano, J, Kannan, K, Tsirigos, A, Brück, W, Hofer, S, Brehmer, S, Seiz-Rosenhagen, M, Hänggi, D, Hans, V, Rozsnoki, S, Hansford, J R, Kohlhof, P, Kristensen, B W, Lechner, M, Lopes, B, Mawrin, C, Ketter, R, Kulozik, A, Khatib, Z, Heppner, F, Koch, A, Jouvet, A, Keohane, C, Mühleisen, H, Mueller, W, Pohl, U, Prinz, M, Benner, A, Zapatka, M, Gottardo, N G, Driever, P H, Kramm, C M, Müller, H L, Rutkowski, S, von Hoff, K, Frühwald, M C, Gnekow, A, Fleischhack, G, Tippelt, S, Calaminus, G, Monoranu, C-M, Perry, A, Jones, C, Jacques, T S, Radlwimmer, B, Gessi, M, Pietsch, T, Schramm, J, Schackert, G, Westphal, M, Reifenberger, G, Wesseling, P, Weller, M, Collins, V P, Blümcke, I, Bendszus, M, Debus, J R, Huang, A, Jabado, N, Northcott, P A, Paulus, W, Gajjar, A, Robinson, G W, Taylor, M D, Jaunmuktane, Z, Ryzhova, M, Platten, M, Unterberg, A, Wick, W, Karajannis, M A, Mittelbronn, M, Acker, T, Hartmann, C, Aldape, K, Schüller, U, Buslei, R, Lichter, P, Kool, M, Herold-Mende, C, Ellison, D W, Hasselblatt, M, Snuderl, M, Brandner, S, Korshunov, A, von Deimling, A & Pfister, S M 2018, ' DNA methylation-based classification of central nervous system tumours ', Nature, vol. 555, no. 7697, pp. 469-474 . https://doi.org/10.1038/nature26000
Capper, D, Jones, D T W, Sill, M, Hovestadt, V, Schrimpf, D, Sturm, D, Koelsche, C, Sahm, F, Chavez, L, Reuss, D E, Kratz, A, Wefers, A K, Huang, K, Pajtler, K W, Schweizer, L, Stichel, D, Olar, A, Engel, N W, Lindenberg, K, Harter, P N, Braczynski, A K, Plate, K H, Dohmen, H, Garvalov, B K, Coras, R, Hölsken, A, Hewer, E, Bewerunge-Hudler, M, Schick, M, Fischer, R, Beschorner, R, Schittenhelm, J, Staszewski, O, Wani, K, Varlet, P, Pages, M, Temming, P, Lohmann, D, Selt, F, Witt, H, Milde, T, Witt, O, Aronica, E, Giangaspero, F, Rushing, E, Scheurlen, W, Geisenberger, C, Rodriguez, F J, Becker, A, Preusser, M, Haberler, C, Bjerkvig, R, Cryan, J, Farrell, M, Deckert, M, Hench, J, Frank, S, Serrano, J, Kannan, K, Tsirigos, A, Brück, W, Hofer, S, Brehmer, S, Seiz-Rosenhagen, M, Hänggi, D, Hans, V, Rozsnoki, S, Hansford, J R, Kohlhof, P, Kristensen, B W, Lechner, M, Lopes, B, Mawrin, C, Ketter, R, Kulozik, A, Khatib, Z, Heppner, F, Koch, A, Jouvet, A, Keohane, C, Mühleisen, H, Mueller, W, Pohl, U, Prinz, M, Benner, A, Zapatka, M, Gottardo, N G, Driever, P H, Kramm, C M, Müller, H L, Rutkowski, S, Von Hoff, K, Frühwald, M C, Gnekow, A, Fleischhack, G, Tippelt, S, Calaminus, G, Monoranu, C M, Perry, A, Jones, C, Jacques, T S, Radlwimmer, B, Gessi, M, Pietsch, T, Schramm, J, Schackert, G, Westphal, M, Reifenberger, G, Wesseling, P, Weller, M, Collins, V P, Blümcke, I, Bendszus, M, Debus, J, Huang, A, Jabado, N, Northcott, P A, Paulus, W, Gajjar, A, Robinson, G W, Taylor, M D, Jaunmuktane, Z, Ryzhova, M, Platten, M, Unterberg, A, Wick, W, Karajannis, M A, Mittelbronn, M, Acker, T, Hartmann, C, Aldape, K, Schüller, U, Buslei, R, Lichter, P, Kool, M, Herold-Mende, C, Ellison, D W, Hasselblatt, M, Snuderl, M, Brandner, S, Korshunov, A, Von Deimling, A & Pfister, S M 2018, ' DNA methylation-based classification of central nervous system tumours ', Nature, vol. 555, no. 7697, pp. 469-474 . https://doi.org/10.1038/nature26000
Nature, 555(7697), 469. Nature Publishing Group
Capper, D, Jones, D T W, Sill, M, Hovestadt, V, Schrimpf, D, Sturm, D, Koelsche, C, Sahm, F, Chavez, L, Reuss, D E, Kratz, A, Wefers, A K, Huang, K, Pajtler, K W, Schweizer, L, Stichel, D, Olar, A, Engel, N W, Lindenberg, K, Harter, P N, Braczynski, A K, Plate, K H, Dohmen, H, Garvalov, B K, Coras, R, Hölsken, A, Hewer, E, Bewerunge-Hudler, M, Schick, M, Fischer, R, Beschorner, R, Schittenhelm, J, Staszewski, O, Wani, K, Varlet, P, Pages, M, Temming, P, Lohmann, D, Selt, F, Witt, H, Milde, T, Witt, O, Aronica, E, Giangaspero, F, Rushing, E, Scheurlen, W, Geisenberger, C, Rodriguez, F J, Becker, A, Preusser, M, Haberler, C, Bjerkvig, R, Cryan, J, Farrell, M, Deckert, M, Hench, J R, Frank, S, Serrano, J, Kannan, K, Tsirigos, A, Brück, W, Hofer, S, Brehmer, S, Seiz-Rosenhagen, M, Hänggi, D, Hans, V, Rozsnoki, S, Hansford, J R, Kohlhof, P, Kristensen, B W, Lechner, M, Lopes, B, Mawrin, C, Ketter, R, Kulozik, A, Khatib, Z, Heppner, F, Koch, A, Jouvet, A, Keohane, C, Mühleisen, H, Mueller, W, Pohl, U, Prinz, M, Benner, A, Zapatka, M, Gottardo, N G, Driever, P H, Kramm, C M, Müller, H L, Rutkowski, S, von Hoff, K, Frühwald, M C, Gnekow, A, Fleischhack, G, Tippelt, S, Calaminus, G, Monoranu, C-M, Perry, A, Jones, C, Jacques, T S, Radlwimmer, B, Gessi, M, Pietsch, T, Schramm, J, Schackert, G, Westphal, M, Reifenberger, G, Wesseling, P, Weller, M, Collins, V P, Blümcke, I, Bendszus, M, Debus, J R, Huang, A, Jabado, N, Northcott, P A, Paulus, W, Gajjar, A, Robinson, G W, Taylor, M D, Jaunmuktane, Z, Ryzhova, M, Platten, M, Unterberg, A, Wick, W, Karajannis, M A, Mittelbronn, M, Acker, T, Hartmann, C, Aldape, K, Schüller, U, Buslei, R, Lichter, P, Kool, M, Herold-Mende, C, Ellison, D W, Hasselblatt, M, Snuderl, M, Brandner, S, Korshunov, A, von Deimling, A & Pfister, S M 2018, ' DNA methylation-based classification of central nervous system tumours ', Nature, vol. 555, no. 7697, pp. 469-474 . https://doi.org/10.1038/nature26000
Capper, D, Jones, D T W, Sill, M, Hovestadt, V, Schrimpf, D, Sturm, D, Koelsche, C, Sahm, F, Chavez, L, Reuss, D E, Kratz, A, Wefers, A K, Huang, K, Pajtler, K W, Schweizer, L, Stichel, D, Olar, A, Engel, N W, Lindenberg, K, Harter, P N, Braczynski, A K, Plate, K H, Dohmen, H, Garvalov, B K, Coras, R, Hölsken, A, Hewer, E, Bewerunge-Hudler, M, Schick, M, Fischer, R, Beschorner, R, Schittenhelm, J, Staszewski, O, Wani, K, Varlet, P, Pages, M, Temming, P, Lohmann, D, Selt, F, Witt, H, Milde, T, Witt, O, Aronica, E, Giangaspero, F, Rushing, E, Scheurlen, W, Geisenberger, C, Rodriguez, F J, Becker, A, Preusser, M, Haberler, C, Bjerkvig, R, Cryan, J, Farrell, M, Deckert, M, Hench, J, Frank, S, Serrano, J, Kannan, K, Tsirigos, A, Brück, W, Hofer, S, Brehmer, S, Seiz-Rosenhagen, M, Hänggi, D, Hans, V, Rozsnoki, S, Hansford, J R, Kohlhof, P, Kristensen, B W, Lechner, M, Lopes, B, Mawrin, C, Ketter, R, Kulozik, A, Khatib, Z, Heppner, F, Koch, A, Jouvet, A, Keohane, C, Mühleisen, H, Mueller, W, Pohl, U, Prinz, M, Benner, A, Zapatka, M, Gottardo, N G, Driever, P H, Kramm, C M, Müller, H L, Rutkowski, S, Von Hoff, K, Frühwald, M C, Gnekow, A, Fleischhack, G, Tippelt, S, Calaminus, G, Monoranu, C M, Perry, A, Jones, C, Jacques, T S, Radlwimmer, B, Gessi, M, Pietsch, T, Schramm, J, Schackert, G, Westphal, M, Reifenberger, G, Wesseling, P, Weller, M, Collins, V P, Blümcke, I, Bendszus, M, Debus, J, Huang, A, Jabado, N, Northcott, P A, Paulus, W, Gajjar, A, Robinson, G W, Taylor, M D, Jaunmuktane, Z, Ryzhova, M, Platten, M, Unterberg, A, Wick, W, Karajannis, M A, Mittelbronn, M, Acker, T, Hartmann, C, Aldape, K, Schüller, U, Buslei, R, Lichter, P, Kool, M, Herold-Mende, C, Ellison, D W, Hasselblatt, M, Snuderl, M, Brandner, S, Korshunov, A, Von Deimling, A & Pfister, S M 2018, ' DNA methylation-based classification of central nervous system tumours ', Nature, vol. 555, no. 7697, pp. 469-474 . https://doi.org/10.1038/nature26000
Accurate pathological diagnosis is crucial for optimal management of patients with cancer. For the approximately 100 known tumour types of the central nervous system, standardization of the diagnostic process has been shown to be particularly challen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5047d9e6db898ab95d5c17d081d6d9b6
https://doi.org/10.1038/nature26000
https://doi.org/10.1038/nature26000
Autor:
Tom Mikkelsen, Rogier Versteeg, Christelle Dufour, Jens Schittenhelm, Umut H. Toprak, Eleonora Aronica, Sariah Allen, Stefan M. Pfister, Arie Perry, Dominique Figarella-Branger, David T.W. Jones, Stephan Wolf, Irene Slavc, Christian Mawrin, Pieter Wesseling, Nada Jabado, Cynthia Cowdrey, David W. Ellison, Andreas von Deimling, Jörg Felsberg, Michael A. Grotzer, Pascale Varlet, Michael C. Frühwald, Volker Hovestadt, Timothy E. Van Meter, Gnanaprakash Balasubramanian, V. Peter Collins, Wolfram Scheurlen, Christian Hagel, Volkmar Hans, Johannes Gojo, Irina Leis, Michael D. Taylor, Catherine Keohane, Marco Prinz, Rachid Drissi, Maria Łastowska, Istvan Vajtai, Anne Jouvet, Sonika Dahiya, Marietta Wolter, Matthias Schlesner, Till Milde, Chris Jones, Pascal Johann, Kristian W. Pajtler, Anna Maria Buccoliero, Marina Ryzhova, David Scheie, Kenneth Aldape, Matija Snuderl, Martin Ebinger, Bret C. Mobley, Sebastian Brabetz, Joanna J. Phillips, Tarek Shalaby, Silvia Hofer, Christian Koelsche, Christel Herold-Mende, Barbara C. Worst, Martin U. Schuhmann, Jüri Reimand, Walter Berger, Stephan Frank, Diana Carvalho, Daniela Lötsch, Christof M. Kramm, Amar Gajjar, David Capper, Peter van Sluis, Ivo Buchhalter, Christine Haberler, Katja von Hoff, Stefan Rutkowski, Roland Eils, Martin Hasselblatt, Ulrich Schüller, Maryam Fouladi, Jochen Rößler, Guido Reifenberger, Brent A. Orr, Andrew S. Moore, Alan Mackay, Marc Remke, André O. von Bueren, Felix Sahm, Jan Koster, Karel Zitterbart, Dominik Sturm, Paul A. Northcott, Peter Lichter, Matthias A. Karajannis, Stefan Holm, Martin Sill, Wiesława Grajkowska, Stéphanie Puget, Felice Giangaspero, Marcel Kool, Reinhard Schneppenheim, Lynn Ann Forrester, Mariarita Santi, Torsten Pietsch, Camelia M. Monoranu, Richard Volckmann, Iris Fried, Matthew Schniederjan, Andrey Korshunov, Elke Pfaff, Rainer Grobholz, Jacques Grill
Publikováno v:
Cell, Vol. 164, No 5 (2016) pp. 1060-1072
Cell, 164, 5, pp. 1060-72
Cell, 164(5), 1060-1072. Cell Press
Sturm, D, Orr, B A, Toprak, U H, Hovestadt, V, Jones, D T W, Capper, D, Sill, M, Buchhalter, I, Northcott, P A, Leis, I, Ryzhova, M, Koelsche, C, Pfaff, E, Allen, S J, Balasubramanian, G, Worst, B C, Pajtler, K W, Brabetz, S, Johann, P D, Sahm, F, Reimand, J, Mackay, A, Carvalho, D M, Remke, M, Phillips, J J, Perry, A, Cowdrey, C, Drissi, R, Fouladi, M, Giangaspero, F, Lastowska, M, Grajkowska, W, Scheurlen, W, Pietsch, T, Hagel, C, Gojo, J, Loetsch, D, Berger, W, Slavc, I, Haberler, C, Jouvet, A, Holm, S, Hofer, S, Prinz, M, Keohane, C, Fried, I, Mawrin, C, Scheie, D, Mobley, B C, Schniederjan, M J, Santi, M, Buccoliero, A M, Dahiya, S, Kramm, C M, von Bueren, A O, von Hoff, K, Rutkowski, S, Herold-Mende, C, Fruehwald, M C, Milde, T, Hasselblatt, M, Wesseling, P, Roessler, J, Schueller, U, Ebinger, M, Schittenhelm, J, Frank, S, Grobholz, R, Vajtai, I, Hans, V, Schneppenheim, R, Zitterbart, K, Collins, V P, Aronica, E, Varlet, P, Puget, S, Dufour, C, Grill, J, Figarella-Branger, D, Wolter, M, Schuhmann, M U, Shalaby, T, Grotzer, M, van Meter, T, Monoranu, C-M, Felsberg, J, Reifenberger, G, Snuderl, M, Forrester, L A, Koster, J, Versteeg, R, Volckmann, R, van Sluis, P, Wolf, S, Mikkelsen, T, Gajjar, A, Aldape, K, Moore, A S, Taylor, M D, Jones, C, Jabado, N, Karajannis, M A, Eils, R, Schlesner, M, Lichter, P, von Deimling, A, Pfister, S M, Ellison, D W, Korshunov, A & Kool, M 2016, ' New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs ', Cell, vol. 164, no. 5, pp. 1060-1072 . https://doi.org/10.1016/j.cell.2016.01.015
Cell
Cell, 2016, 164, pp.1060-1072. ⟨10.1016/j.cell.2016.01.015⟩
Cell, Elsevier, 2016, 164, pp.1060-1072. ⟨10.1016/j.cell.2016.01.015⟩
Cell, 164, 1060-72
Cell, 164(5), 1060. Cell Press
Cell, 164, 5, pp. 1060-72
Cell, 164(5), 1060-1072. Cell Press
Sturm, D, Orr, B A, Toprak, U H, Hovestadt, V, Jones, D T W, Capper, D, Sill, M, Buchhalter, I, Northcott, P A, Leis, I, Ryzhova, M, Koelsche, C, Pfaff, E, Allen, S J, Balasubramanian, G, Worst, B C, Pajtler, K W, Brabetz, S, Johann, P D, Sahm, F, Reimand, J, Mackay, A, Carvalho, D M, Remke, M, Phillips, J J, Perry, A, Cowdrey, C, Drissi, R, Fouladi, M, Giangaspero, F, Lastowska, M, Grajkowska, W, Scheurlen, W, Pietsch, T, Hagel, C, Gojo, J, Loetsch, D, Berger, W, Slavc, I, Haberler, C, Jouvet, A, Holm, S, Hofer, S, Prinz, M, Keohane, C, Fried, I, Mawrin, C, Scheie, D, Mobley, B C, Schniederjan, M J, Santi, M, Buccoliero, A M, Dahiya, S, Kramm, C M, von Bueren, A O, von Hoff, K, Rutkowski, S, Herold-Mende, C, Fruehwald, M C, Milde, T, Hasselblatt, M, Wesseling, P, Roessler, J, Schueller, U, Ebinger, M, Schittenhelm, J, Frank, S, Grobholz, R, Vajtai, I, Hans, V, Schneppenheim, R, Zitterbart, K, Collins, V P, Aronica, E, Varlet, P, Puget, S, Dufour, C, Grill, J, Figarella-Branger, D, Wolter, M, Schuhmann, M U, Shalaby, T, Grotzer, M, van Meter, T, Monoranu, C-M, Felsberg, J, Reifenberger, G, Snuderl, M, Forrester, L A, Koster, J, Versteeg, R, Volckmann, R, van Sluis, P, Wolf, S, Mikkelsen, T, Gajjar, A, Aldape, K, Moore, A S, Taylor, M D, Jones, C, Jabado, N, Karajannis, M A, Eils, R, Schlesner, M, Lichter, P, von Deimling, A, Pfister, S M, Ellison, D W, Korshunov, A & Kool, M 2016, ' New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs ', Cell, vol. 164, no. 5, pp. 1060-1072 . https://doi.org/10.1016/j.cell.2016.01.015
Cell
Cell, 2016, 164, pp.1060-1072. ⟨10.1016/j.cell.2016.01.015⟩
Cell, Elsevier, 2016, 164, pp.1060-1072. ⟨10.1016/j.cell.2016.01.015⟩
Cell, 164, 1060-72
Cell, 164(5), 1060. Cell Press
Item does not contain fulltext Primitive neuroectodermal tumors of the central nervous system (CNS-PNETs) are highly aggressive, poorly differentiated embryonal tumors occurring predominantly in young children but also affecting adolescents and adult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5ce75bf4ceb1b2f119f15b978d9c6da
https://doi.org/10.1016/j.cell.2016.01.015
https://doi.org/10.1016/j.cell.2016.01.015
