Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Cenfu Wei"'
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 9549 (2022)
The HER2/neu signaling pathway is one of the most frequently mutated in human cancer. Although therapeutics targeting this pathway have good efficacy, cancer cells frequently develop resistance. The HER2 gene encodes the full-length HER2 protein, as
Externí odkaz:
https://doaj.org/article/ba29ab2fb76f46398b7c83b58b5a4dde
Autor:
Xiaofei Du, Giorgio Grasselli, Dana H. Simmons, Christopher M. Gomez, Justine Shih, Christian Hansel, Heather K. Titley, Silas E. Busch, Claire Piochon, Cenfu Wei
Publikováno v:
Biological Psychiatry Global Open Science. 2:450-459
Background Autism spectrum disorder (ASD) patients often show altered responses to sensory stimuli as well as motor deficits, including an impairment of delay eyeblink conditioning (EBC), which involves integration of sensory signals in the cerebellu
Publikováno v:
The Cerebellum.
Publikováno v:
The Cerebellum.
MicroRNAs, a class of small RNA regulators, function throughout neurodevelopment, from neural stem cell neurogenesis to neuronal maturation, synaptic formation, and plasticity. α1ACT, a transcription factor (TF), plays a critical role in neonatal ce
Autor:
Xiaofei Du, João L. Carvalho-de-Souza, Natalie Petrossian, Ramon Latorre, Timothy C. Hain, Julia Staisch, Willy Carrasquel-Ursulaez, Christopher M. Gomez, Francisco Bezanilla, Yenisleidy Lorenzo, Michael Xu, Tomoya Kubota, Naileth Gonzalez, Cenfu Wei
Publikováno v:
Proc Natl Acad Sci U S A
Despite a growing number of ion channel genes implicated in hereditary ataxia, it remains unclear how ion channel mutations lead to loss-of-function or death of cerebellar neurons. Mutations in the gene KCNMA1 , encoding the α-subunit of the BK chan
Autor:
Yan Li, Ann C. Palmenberg, Jack Godfrey, Xiaofei Du, Daniel Parviz Hejazi Pastor, Christian Hansel, Jorge Andrade, Giorgio Grasselli, Eshaan R. Rao, Christopher M. Gomez, Cenfu Wei
Publikováno v:
Neuron. 102:770-785.e7
Summary Postnatal cerebellar development is a precisely regulated process involving well-orchestrated expression of neural genes. Neurological phenotypes associated with CACNA1A gene defects have been increasingly recognized, yet the molecular princi