Výsledky vyhledávání - "Cendrine, Cabou"

Akademický článek

PI3Kβ Plays a Key Role in Apolipoprotein A-I-Induced Endothelial Cell Proliferation Through Activation of the Ecto-F1-ATPase/P2Y1 Receptors

Autor: Audrey Castaing-Berthou, Nicole Malet, Claudia Radojkovic, Cendrine Cabou, Stéphanie Gayral, Laurent Olivier Martinez, Muriel Laffargue

Publikováno v: Cellular Physiology and Biochemistry, Vol 42, Iss 2, Pp 579-593 (2017)

Background/Aims: High-density lipoproteins (HDL) exert multiple cardioprotective functions on the arterial wall, including the promotion of endothelial cell survival and proliferation. Among mechanism contributing to endothelial protection, it has be

Externí odkaz: https://doaj.org/article/2bbe027da883465bacb125d6bc1dd117

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Purinergic P2Y Receptors in Endothelium: From Vascular Physiology to Pathology, a Review Based on Recent Advances

Autor: Cendrine Cabou, Laurent O Martinez

The endothelium plays a key role in blood vessel health. At the interface of the blood, it releases several mediators that regulate local processes and that protect against the development of cardiovascular disease. In this interplay, there is increa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c366dab13a27df0c2bdd711d30aab06d
https://doi.org/10.20944/preprints202204.0291.v1

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The Interplay of Endothelial P2Y Receptors in Cardiovascular Health: From Vascular Physiology to Pathology

Autor: Cendrine Cabou, Laurent O. Martinez

Publikováno v: International journal of molecular sciences. 23(11)

The endothelium plays a key role in blood vessel health. At the interface of the blood, it releases several mediators that regulate local processes that protect against the development of cardiovascular disease. In this interplay, there is increasing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7aead75e2c6e8a1fd876be7d30f2e8d
https://pubmed.ncbi.nlm.nih.gov/35682562

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Catalytic dysregulation of SHP2 leading to Noonan syndromes affects platelet signaling and functions

Autor: Benjamin G. Neel, Philippe Valet, Alexandra Mazharian, Yotis A. Senis, Jun Mori, Bernard Payrastre, Cendrine Cabou, Thomas Edouard, Sophie Voisin, Cédric Garcia, Marie Bellio, Sonia Severin, Armelle Yart

Publikováno v: Blood. 134:2304-2317

Src homology 2 domain–containing phosphatase 2 (SHP2), encoded by the PTPN11 gene, is a ubiquitous protein tyrosine phosphatase that is a critical regulator of signal transduction. Germ line mutations in the PTPN11 gene responsible for catalytic ga

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b1cfc4223c2f883ae1350e4908af9a9
https://doi.org/10.1182/blood.2019001543

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Effect of estetrol, a selective nuclear estrogen receptor modulator, in mouse models of arterial and venous thrombosis

Autor: Olivier Lairez, Coralie Fontaine, Bernard Payrastre, Jean-François Arnal, Cédric Garcia, Anne Briaux, Cendrine Cabou, Marion Dupuis, Emmanuelle Noirrit-Esclassan, Jean-Michel Foidart, Françoise Lenfant, Marie-Cécile Valéra

Publikováno v: Molecular and Cellular Endocrinology. 477:132-139

Estetrol (E4) is a natural estrogen synthesized exclusively during pregnancy by the human fetal liver, and the physiological role of this hormone is unknown. Interestingly, E4 was recently evaluated in preclinical and phase II-III clinical studies in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::616234ec190cbda9f4d0a10c098ca1ce
https://doi.org/10.1016/j.mce.2018.06.010

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Pharmacological inhibition of the F 1 -ATPase/P2Y 1 pathway suppresses the effect of apolipoprotein A1 on endothelial nitric oxide synthesis and vasorelaxation

Autor: Paula Honorato, Marcelo González, Cendrine Cabou, Laure Frayssinhes, Bernard Masri, Claudio Aguayo, Valeria Aguilera, Laurent O. Martinez, Thibaut Duparc, Audren Fournel, Marcelo León, Anne Abot, Claude Knauf, Claudia Radojkovic, Guillaume Combes, Luis Briceño, Nicol Parada, Lamia Ghezali

Publikováno v: Acta Physiologica
Acta Physiologica, Wiley, 2019, 1, pp.e13268. ⟨10.1111/apha.13268⟩
Acta Physiologica, Wiley, 2019, 1 (3), pp.e13268. ⟨10.1111/apha.13268⟩
Acta Physiologica 3 (226), e13268. (2019)
Acta Physiologica, 2019, 1 (3), pp.e13268. ⟨10.1111/apha.13268⟩

C. Radojkovic and L.O. Martinez are co-senior authors.; International audience; AIM:The contribution of apolipoprotein A1 (APOA1), the major apolipoprotein of high-density lipoprotein (HDL), to endothelium-dependent vasodilatation is unclear, and the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89721503e92f900cb14dd61aa841a880
https://www.hal.inserm.fr/inserm-02393118

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Pharmacological inhibition of the F

Autor: Cendrine, Cabou, Paula, Honorato, Luis, Briceño, Lamia, Ghezali, Thibaut, Duparc, Marcelo, León, Guillaume, Combes, Laure, Frayssinhes, Audren, Fournel, Anne, Abot, Bernard, Masri, Nicol, Parada, Valeria, Aguilera, Claudio, Aguayo, Claude, Knauf, Marcelo, González, Claudia, Radojkovic, Laurent O, Martinez

Publikováno v: Acta physiologica (Oxford, England). 226(3)

The contribution of apolipoprotein A1 (APOA1), the major apolipoprotein of high-density lipoprotein (HDL), to endothelium-dependent vasodilatation is unclear, and there is little information regarding endothelial receptors involved in this effect. Ec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7a669bb8f74c881fea331b5aff5f0c9e
https://pubmed.ncbi.nlm.nih.gov/30821416

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Impact of PI3Kα (Phosphoinositide 3-Kinase Alpha) Inhibition on Hemostasis and Thrombosis

Autor: Bernard Payrastre, Ashraf Ragab, Cendrine Cabou, Typhaine Anquetil, Cécile V. Denis, Marie-Pierre Gratacap, Sonia Severin, Romain Solinhac, Pierre-Alexandre Laurent, Béatrice Hechler, Pierre Mangin, Bart Vanhaesebroeck

Publikováno v: Arteriosclerosis, thrombosis, and vascular biology. 38(9)

Objective— PI3Kα (phosphoinositide 3-kinase alpha) is a therapeutic target in oncology, but its role in platelets and thrombosis remains ill characterized. In this study, we have analyzed the role of PI3Kα in vitro, ex vivo, and in vivo in 2 mode

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5ecf48e5a76bd999b75e0f8d72ba3ba
https://pubmed.ncbi.nlm.nih.gov/30354258

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Essential role of class II PI3K-C2α in platelet membrane morphology

Autor: Gaëtan Chicanne, Childérick Séverac, Bernard Payrastre, Marie-Pierre Gratacap, Frédérique Gaits-Iacovoni, Cendrine Cabou, Bart Vanhaesebroeck, Maria A. Whitehead, Claire Chaussade, Sonia Severin, Colin Valet

Publikováno v: Blood. 126:1128-1137

The physiologic roles of the class II phosphoinositide 3-kinases (PI3Ks) and their contributions to phosphatidylinositol 3-monophosphate (PI3P) and PI(3,4)P2 production remain elusive. Here we report that mice heterozygous for a constitutively kinase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b6e139c0f2bab8c0f7f2176b63ef06eb
https://doi.org/10.1182/blood-2015-03-636670

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Ecto-F1-ATPase/P2Y pathways in metabolic and vascular functions of high density lipoproteins

Autor: Cendrine Cabou, Laeticia Lichtenstein, Laurent O. Martinez, Bertrand Perret, Souad Najib

Publikováno v: Atherosclerosis. 238:89-100

The atheroprotective property of High Density Lipoprotein (HDL) is supported by many epidemiological studies and cellular and in vivo approaches on animal models. While the anti-atherogenic effects of HDL are thought to derive primarily from its role

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47ed4c8e42e399f5709d23725ea49385
https://doi.org/10.1016/j.atherosclerosis.2014.11.017

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