Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Cencen Chu"'
Publikováno v:
Physiological Reports, Vol 11, Iss 10, Pp n/a-n/a (2023)
Abstract The voltage‐gated Nav1.5 channels mediate the fast Na+ current (INa) in cardiomyocytes initiating action potentials and cardiac contraction. Downregulation of INa, as occurs in Brugada syndrome (BrS), causes ventricular arrhythmias. The pr
Externí odkaz:
https://doaj.org/article/59434b1907a146cba2a47087a711a6dd
Autor:
David Cortes, Christopher D. McTiernan, Marc Ruel, Walfre Franco, Cencen Chu, Wenbin Liang, Erik J. Suuronen, Emilio I. Alarcon
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Abstract 3D printing was used to develop an open access device capable of simultaneous electrical and mechanical stimulation of human induced pluripotent stem cells in 6-well plates. The device was designed using Computer-Aided Design (CAD) and 3D pr
Externí odkaz:
https://doaj.org/article/79edc5e6e22f4fa2a09f0979fc660122
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 471:1551-1564
Hydrogen sulfide (H2S) is endogenously produced in pancreatic s cells and its level is elevated in diabetes. Here, we report that H2S affects insulin secretion via two mechanisms that converge on cytosolic free Ca2+ ([Ca2+]i), a key mediator of insul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::866967c96052b37484fd6b989a45ad27
https://doi.org/10.1007/s00424-019-02325-9
https://doi.org/10.1007/s00424-019-02325-9
Publikováno v:
SSRN Electronic Journal.
Background: Both inherited arrhythmogenic diseases (such as Brugada Syndrome, BrS) and heart failure are associated with reduced voltage-gated Na+ current (lNa) which promotes lethal arrhythmias and sudden deaths. We have shown that WNT/β-catenin si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81050fb877ab456ed1878663d3004434
https://doi.org/10.2139/ssrn.3815857
https://doi.org/10.2139/ssrn.3815857
Autor:
Walfre Franco, David Cortes, Marc Ruel, Christopher D. McTiernan, Erik J. Suuronen, Emilio I. Alarcon, Wenbin Liang, Cencen Chu
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
3D printing was used to develop an open access device capable of simultaneous electrical and mechanical stimulation of human induced pluripotent stem cells in 6-well plates. The device was designed using Computer-Aided Design (CAD) and 3D printed wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6505b3e9e4b9fac29c09f59a6d3af508
http://europepmc.org/articles/PMC7347879
http://europepmc.org/articles/PMC7347879
Publikováno v:
Circulation Research. 125
Aims: Both inherited arrhythmogenic diseases (such as Brugada Syndrome) and heart failure are associated with reduced voltage-gated Na + current (I Na ) which promotes lethal arrhythmias and sudden deaths. We and others have shown that Wnt/β-catenin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::039e57b880faae8e2a097f07abe7a82f
https://doi.org/10.1161/res.125.suppl_1.111
https://doi.org/10.1161/res.125.suppl_1.111
Publikováno v:
Pflugers Archiv : European journal of physiology. 471(11-12)
Hydrogen sulfide (H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::82a0d860a26dca0d6a00bf27e8dc0a19
https://pubmed.ncbi.nlm.nih.gov/31713764
https://pubmed.ncbi.nlm.nih.gov/31713764
Autor:
Aizhu, Lu, Maryam, Kamkar, Cencen, Chu, Jerry, Wang, Kaya, Gaudet, Yawen, Chen, Lauren, Lin, Weixin, Liu, Eduardo, Marbán, Wenbin, Liang
Publikováno v:
The Canadian journal of cardiology. 36(4)
Myocardial infarction and heart failure are associated with reduced voltage-gated NaWnt signalling was activated in neonatal rat ventricular myocytes by Wnt3a protein. Adenovirus expressing Wnt3a was injected into the adult rat ventricle. CRISPR/Cas9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bdd994f1c08053d28ac003f4431dc74b
https://pubmed.ncbi.nlm.nih.gov/32046907
https://pubmed.ncbi.nlm.nih.gov/32046907