Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Cencan Xing"'
Autor:
Zehua Zeng, Yuqing Ma, Lei Hu, Bowen Tan, Peng Liu, Yixuan Wang, Cencan Xing, Yuanyan Xiong, Hongwu Du
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Single-cell sequencing is frequently affected by “omission” due to limitations in sequencing throughput, yet bulk RNA-seq may contain these ostensibly “omitted” cells. Here, we introduce the single cell trajectory blending from Bulk
Externí odkaz:
https://doaj.org/article/0dc87be26c624f4cb6b11b305a734a3e
Autor:
Cencan Xing, Zehua Zeng, Yaqi Li, Bo Gong, Weimin Shen, Roshan Shah, Lu Yan, Hongwu Du, Anming Meng
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Activation of nodal genes is critical for mesoderm and endoderm induction. Our previous study reported that zebrafish nodal genes ndr1/squint and ndr2/cyclops are coordinately regulated by maternal Eomesa, Hwa-activated β-catenin (Hwa/β-catenin) si
Externí odkaz:
https://doaj.org/article/a80006aeef0b41438bfbb2765d32efa8
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Nodal proteins provide crucial signals for mesoderm and endoderm induction. In zebrafish embryos, the nodal genes ndr1/squint and ndr2/cyclops are implicated in mesendoderm induction. It remains elusive how ndr1 and ndr2 expression is regulated spati
Externí odkaz:
https://doaj.org/article/00716515314e4e3aa01a254dac1cc9f2
Autor:
Xiaoshuang Zhang, Jinghui Zhang, Cencan Xing, Zehua Zeng, Wenhuan Guo, Roshan Shah, Yongzhong Bian, Jingjie Yang, Wangyu Bi, Donghui Wang, Yingxian Li, Hongwu Du
Publikováno v:
Cytotherapy. 24:59-71
Background aims Stem cell therapy is a novel therapy being explored for AD. The molecular mechanism of its effect is still unclear. The authors investigated the effects and mechanism by injection of SHEDs into an AD mouse model. Methods SHEDs were cu
Cellular state identification and trajectory inference enable reconstructions of cell fate dynamics from single-cell RNA sequencing. However, the identification of cell fate trajectories requires a large number of computational resources or known bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c4686d8684841be01d938b56eeb66be
https://doi.org/10.1101/2022.09.28.510020
https://doi.org/10.1101/2022.09.28.510020
Autor:
Weimin Shen, Bo Gong, Cencan Xing, Lin Zhang, Jiawei Sun, Yuling Chen, Changmei Yang, Lu Yan, Luxi Chen, Likun Yao, Guangyuan Li, Haiteng Deng, Xiaotong Wu, Anming Meng
Publikováno v:
Cell. 185:4954-4970.e20
Nuclear pore complexes (NPCs) are channels for nucleocytoplasmic transport of proteins and RNAs. However, it remains unclear whether composition, structure, and permeability of NPCs dynamically change during the cleavage period of vertebrate embryos
Autor:
Lin Zhang, Guangyuan Li, Bo Gong, Yuling Chen, Cencan Xing, Haiteng Deng, Likun Yao, Anming Meng, Changmei Yang, Luxi Chen, Weimin Shen
Publikováno v:
SSRN Electronic Journal.
Highlights ● NPCs matures gradually in the zebrafish embryo after fertilization ● Maternal TFs cannot transport into nuclei efficiently in embryos before ZGA ● Nuclear pore complex maturity controls TFs nuclear transport and ZGA onset ● Dysfu
Autor:
Bo Leng, Yutian Pan, Wenjuan Zhang, Xiumin Li, Yi Su, Yu Xue, Xuqiao Mei, Cencan Xing, Jiaofen Lin, Xu Jingjin, Juhui Qiu, Yiqun Huang, Jinmei Lin
Publikováno v:
Biochemical and Biophysical Research Communications. 496:654-660
Osteoporosis is a global public health concern and, it can result from numerous pathogenic mechanisms, many of which are closely related with age, nutritional disorders, endocrine imbalance, or adverse drug side effects presented by glucocorticoids,
Publikováno v:
Biochemical and biophysical research communications. 508(2)
With co-treatment of potassium oxonate (PO) and xanthine sodium salt (XSS), a zebrafish larva model of acute hyperuricemia has been constructed for the first time. The results show PO 200 μM + XSS 10 μM, PO 300 μM + XSS 15 μM, and PO 400 μM + XS
Publikováno v:
Journal of Molecular Cell Biology. 7:48-61
The zebrafish sensory posterior lateral line (pLL) has become an attractive model for studying collective cell migration and cell morphogenesis. Recent studies have indicated that chemokine, Wnt/β-catenin, Fgf, and Delta-Notch signaling pathways par