Zobrazeno 1 - 10
of 291
pro vyhledávání: '"Cem Akin"'
Autor:
Alan L. Shields, Fiona Taylor, Roger E. Lamoureux, Brad Padilla, Kas Severson, Tanya Green, Anthony L. Boral, Cem Akin, Frank Siebenhaar, Brenton Mar
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 18, Iss 1, Pp 1-11 (2023)
Abstract Background The Indolent Systemic Mastocytosis Symptom Assessment Form (ISM-SAF) (©Blueprint Medicines Corporation), a 12-item daily diary that assesses 11 signs and symptoms of indolent systemic mastocytosis (ISM) and smoldering systemic ma
Externí odkaz:
https://doaj.org/article/94b4b613e6f74b538a3b3852443317a6
Autor:
Jason Gotlib, Mariana Castells, Hanneke Oude Elberink, Frank Siebenhaar, Karin Hartmann, Sigurd Broesby-Olsen, Tracy I. George, Jens Panse, Ivan Alvarez-Twose, Deepti Radia, Tsewang Tashi, Cristina Bulai Livideanu, Vito Sabato, Paul Van Daele, Sonia Cerquozzi, Ingunn Dybedal, Andreas Reiter, Celalettin Ustun, Philippe Schafhausen, Prithviraj Bose, Daniel J. Deangelo, Lindsay Rein, Pankit Vachhani, Massimo Triggiani, Mark Rafferty, Nauman Butt, Stephen Oh, Friederike Wortmann, Johanna Ungerstedt, Minakshi Taparia, Andrew T. Kuykendall, Cecilia Arana Yi, Mattias Mattsson, William Shomali, Matthew Giannetti, Ilda Bidollari, Hui-Min Lin, Robyn Scherber, Maria Roche, Cem Akin, Marcus Maurer
Publikováno v:
HemaSphere, Vol 7, p e7796003 (2023)
Externí odkaz:
https://doaj.org/article/060bc67958084d12a5551ad176dad26a
Autor:
Peter Valent, Cem Akin, Michel Arock, Karoline V. Gleixner, Hildegard Greinix, Olivier Hermine, Hans-Peter Horny, Daniel Ivanov, Alberto Orfao, Werner Rabitsch, Andreas Reiter, Axel Schulenburg, Karl Sotlar, Wolfgang R. Sperr, Celalettin Ustun
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15125 (2023)
Advanced systemic mastocytosis (SM) is a heterogeneous group of myeloid neoplasms characterized by an uncontrolled expansion of mast cells (MC) in one or more internal organs, SM-induced tissue damage, and poor prognosis. Advanced SM can be categoriz
Externí odkaz:
https://doaj.org/article/6cb7db1987fb4a19b16cbf0a80918070
Autor:
Fiona Taylor, Cem Akin, Roger E. Lamoureux, Brad Padilla, Tanya Green, Anthony L. Boral, Iyar Mazar, Brenton Mar, Alan L. Shields, Frank Siebenhaar
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-12 (2021)
Abstract Background Advanced systemic mastocytosis (AdvSM), indolent systemic mastocytosis (ISM), and smoldering systemic mastocytosis (SSM) are rare diseases characterized by neoplastic mast cell infiltration of more than one organ. A content-valid
Externí odkaz:
https://doaj.org/article/e7491e39c049481e9d007aca4e635049
Autor:
Brad Padilla, Alan L. Shields, Fiona Taylor, Xiaoran Li, Jeffrey Mcdonald, Tanya Green, Anthony L. Boral, Hui-Min Lin, Cem Akin, Frank Siebenhaar, Brenton Mar
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-10 (2021)
Abstract Background Indolent systemic mastocytosis (ISM) is a rare, clonal mast cell neoplasm characterized by severe, unpredictable symptoms. The Indolent Systemic Mastocytosis Symptom Assessment Form (ISM-SAF) items compose a Total Symptom Score (T
Externí odkaz:
https://doaj.org/article/f99dc0e48e5b4368acd4c26be63b00b4
Autor:
Peter Valent, Cem Akin, Karin Hartmann, Ivan Alvarez-Twose, Knut Brockow, Olivier Hermine, Marek Niedoszytko, Juliana Schwaab, Jonathan J. Lyons, Melody C. Carter, Hanneke Oude Elberink, Joseph H. Butterfield, Tracy I. George, Georg Greiner, Celalettin Ustun, Patrizia Bonadonna, Karl Sotlar, Gunnar Nilsson, Mohamad Jawhar, Frank Siebenhaar, Sigurd Broesby-Olsen, Selim Yavuz, Roberta Zanotti, Magdalena Lange, Boguslaw Nedoszytko, Gregor Hoermann, Mariana Castells, Deepti H. Radia, Javier I. Muñoz-Gonzalez, Wolfgang R. Sperr, Massimo Triggiani, Hanneke C. Kluin-Nelemans, Stephen J. Galli, Lawrence B. Schwartz, Andreas Reiter, Alberto Orfao, Jason Gotlib, Michel Arock, Hans-Peter Horny, Dean D. Metcalfe
Publikováno v:
HemaSphere, Vol 5, Iss 11, p e646 (2021)
Mastocytosis is a hematologic neoplasm characterized by expansion and focal accumulation of neoplastic mast cells (MC) in diverse organs, including the skin, bone marrow (BM), spleen, liver, and gastrointestinal tract. The World Health Organization c
Externí odkaz:
https://doaj.org/article/baa6c70f9bed4d09abd7657782291f35
Autor:
Celalettin Ustun, Elizabeth Morgan, Erica E. M. Moodie, Sheeja Pullarkat, Cecilia Yeung, Sigurd Broesby‐Olsen, Robert Ohgami, Young Kim, Wolfgang Sperr, Hanne Vestergaard, Dong Chen, Philip M. Kluin, Michelle Dolan, Krzysztof Mrózek, David Czuchlewski, Hans‐Peter Horny, Tracy I. George, Thomas Kielsgaard Kristensen, Nam K. Ku, Cecilia Arana Yi, Michael Boe Møller, Guido Marcucci, Linda Baughn, Ana‐Iris Schiefer, J. R. Hilberink, Vinod Pullarkat, Ryan Shanley, Jessica Kohlschmidt, Janie Coulombe, Amandeep Salhotra, Lori Soma, Christina Cho, Michael A. Linden, Cem Akin, Jason Gotlib, Gregor Hoermann, Jason Hornick, Ryo Nakamura, Joachim Deeg, Clara D. Bloomfield, Daniel Weisdorf, Mark R. Litzow, Peter Valent, Gerwin Huls, Miguel‐Angel Perales, Gautam Borthakur
Publikováno v:
Cancer Medicine, Vol 7, Iss 9, Pp 4447-4455 (2018)
Abstract Background Although the prognosis of core‐binding factor (CBF) acute myeloid leukemia (AML) is better than other subtypes of AML, 30% of patients still relapse and may require allogeneic hematopoietic cell transplantation (alloHCT). Howeve
Externí odkaz:
https://doaj.org/article/094eb1a2e98b464ea81e0fe6a9fdcc3c
Proposed Terminology and Classification of Pre-Malignant Neoplastic Conditions: A Consensus Proposal
Autor:
Peter Valent, Cem Akin, Michel Arock, Christoph Bock, Tracy I. George, Stephen J. Galli, Jason Gotlib, Torsten Haferlach, Gregor Hoermann, Olivier Hermine, Ulrich Jäger, Lukas Kenner, Hans Kreipe, Ravindra Majeti, Dean D. Metcalfe, Alberto Orfao, Andreas Reiter, Wolfgang R. Sperr, Philipp B. Staber, Karl Sotlar, Charles Schiffer, Giulio Superti-Furga, Hans-Peter Horny
Publikováno v:
EBioMedicine, Vol 26, Iss C, Pp 17-24 (2017)
Cancer evolution is a step-wise non-linear process that may start early in life or later in adulthood, and includes pre-malignant (indolent) and malignant phases. Early somatic changes may not be detectable or are found by chance in apparently health
Externí odkaz:
https://doaj.org/article/96962f26c4874573a72884840f5fa579
Autor:
Michel Arock, Ghaith Wedeh, Gregor Hoermann, Siham Bibi, Cem Akin, Barbara Peter, Karoline V. Gleixner, Karin Hartmann, Joseph H. Butterfield, Dean D. Metcalfe, Peter Valent
Publikováno v:
Haematologica, Vol 103, Iss 11 (2018)
Mastocytosis is a term used to denote a group of rare diseases characterized by an abnormal accumulation of neoplastic mast cells in various tissues and organs. In most patients with systemic mastocytosis, the neoplastic cells carry activating mutati
Externí odkaz:
https://doaj.org/article/dc75137b7b6942c2804e59269d3c8d19
Autor:
Jan Romantowski, Aleksandra Górska, Marek Niedoszytko, Theo Gulen, Marta Gruchała-Niedoszytko, Bogusław Nedoszytko, Magdalena Lange, Knut Brockow, Michel Arock, Cem Akin, Peter Valent
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 3, p 1454 (2021)
Primary and secondary mast cell activation syndromes (MCAS) can occur in patients with mastocytosis. During the past few years our knowledge about the pathogenesis and disease-triggering mechanisms in MCAS and mastocytosis have increased substantiall
Externí odkaz:
https://doaj.org/article/a0f464358ebd4a83ab5fa18e099a594a