Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Celvie L, Yuan"'
Autor:
Cai Zhang, Joonbae Seo, Kazutoshi Murakami, Esam S. B. Salem, Elise Bernhard, Vishnupriya J. Borra, Kwangmin Choi, Celvie L. Yuan, Calvin C. Chan, Xiaoting Chen, Taosheng Huang, Matthew T. Weirauch, Senad Divanovic, Nathan R. Qi, Hala Einakat Thomas, Carol A. Mercer, Haruhiko Siomi, Takahisa Nakamura
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
The RNA-induced silencing complex (RISC) represses gene expression via micro-RNA guided mRNA silencing. Here, the authors show that RISC component Argonaute 2 in the liver regulates energy metabolism by inducing microRNAs that cause metabolic disrupt
Externí odkaz:
https://doaj.org/article/38c391e9f41444b882b89e0d90e18efc
Autor:
Takahisa Nakamura, Ryan C. Kunz, Cai Zhang, Taishi Kimura, Celvie L. Yuan, Brenna Baccaro, Yuka Namiki, Steven P. Gygi, Gökhan S. Hotamisligil
Publikováno v:
Cell Reports, Vol 11, Iss 2, Pp 295-307 (2015)
Aberrant stress and inflammatory responses are key factors in the pathogenesis of obesity and metabolic dysfunction, and the double-stranded RNA-dependent kinase (PKR) has been proposed to play an important role in integrating these pathways. Here, w
Externí odkaz:
https://doaj.org/article/317f8e3d842c4ff381a6c698c808cbdc
Autor:
Minjie Wei, Zhenhua Chen, Huilin Huang, Jun Liu, Ke-Ren Zhou, Markus Müschen, Juan Du, Xi Jiang, Shu Tao, Chenying Li, Mingli Sun, Hang Yin, Jianjun Chen, Xiwei Wu, Gang Xiao, Yueh-Chiang Hu, Xi Qin, Franziska Auer, Ying Qing, Jian-Hua Yang, Celvie L. Yuan, Jun-Lin Guan, Lei Dong, Chao Shen, Hanjun Qin, Chuan He, Gang Huang, Boxuan Simen Zhao, Huizhe Wu, Hengyou Weng, Wen-Ju Sun, Yunzhu Dong, Yile Zhou, Liang-Hu Qu, Zhike Lu, Rui Su, Lars Klemm, Zhixiang Zuo, Miao Sun, Xiaolan Deng, Tong Wu, Ana Mesquita
Publikováno v:
Nature. 567:414-419
DNA and histone modifications have notable effects on gene expression1. Being the most prevalent internal modification in mRNA, the N6-methyladenosine (m6A) mRNA modification is as an important post-transcriptional mechanism of gene regulation2–4 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec9971bb9405907554d87e9df7e2574c
https://doi.org/10.1038/s41586-019-1016-7
https://doi.org/10.1038/s41586-019-1016-7
Autor:
Ana Mesquita, Hailing Shi, Wen-Ju Sun, Stefan Hüttelmaier, Xi Jiang, Huilin Huang, Minjie Wei, Boxuan Simen Zhao, Jianjun Chen, Lei Dong, Yungui Wang, Xi Qin, Yueh-Chiang Hu, Sigrid Nachtergaele, Miao Sun, Kenneth D. Greis, Chang Liu, Kyle Ferchen, Rui Su, Jennifer R. Skibbe, Celvie L. Yuan, Huizhe Wu, Liang-Hu Qu, Xiaolan Deng, Chuan He, Chao Hu, Jian-Hua Yang, Jun-Lin Guan, Chenying Li, Hengyou Weng
Publikováno v:
Nature cell biology
N6-methyladenosine (m6A) is the most prevalent modification in eukaryotic messenger RNAs (mRNAs) and is interpreted by its readers, such as YTH domain-containing proteins, to regulate mRNA fate. Here, we report the insulin-like growth factor 2 mRNA-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca65e7e08bbb21521ab9f96800ebca04
http://europepmc.org/articles/PMC5826585
http://europepmc.org/articles/PMC5826585
Autor:
Huilin, Huang, Hengyou, Weng, Keren, Zhou, Tong, Wu, Boxuan Simen, Zhao, Mingli, Sun, Zhenhua, Chen, Xiaolan, Deng, Gang, Xiao, Franziska, Auer, Lars, Klemm, Huizhe, Wu, Zhixiang, Zuo, Xi, Qin, Yunzhu, Dong, Yile, Zhou, Hanjun, Qin, Shu, Tao, Juan, Du, Jun, Liu, Zhike, Lu, Hang, Yin, Ana, Mesquita, Celvie L, Yuan, Yueh-Chiang, Hu, Wenju, Sun, Rui, Su, Lei, Dong, Chao, Shen, Chenying, Li, Ying, Qing, Xi, Jiang, Xiwei, Wu, Miao, Sun, Jun-Lin, Guan, Lianghu, Qu, Minjie, Wei, Markus, Müschen, Gang, Huang, Chuan, He, Jianhua, Yang, Jianjun, Chen
Publikováno v:
Nature
DNA and histone modifications exhibit noticeable impacts on gene expression1. Being the most prevalent internal modification in mRNA, N6-Methyladenosine (m6A) mRNA modification emerges as an important post-transcriptional mechanism of gene regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::354f711174bdd07c716380b503f6a51d
https://pubmed.ncbi.nlm.nih.gov/30867593
https://pubmed.ncbi.nlm.nih.gov/30867593
Autor:
Rui Su, Wen-Ju Sun, Huizhe Wu, Liang-Hu Qu, Chang Liu, Kenneth D. Greis, Xi Jiang, Yungui Wang, Boxuan Simen Zhao, Jianjun Chen, Celvie L. Yuan, Chenying Li, Chao Hu, Miao Sun, Sigrid Nachtergaele, Jian-Hua Yang, Kyle Ferchen, Hengyou Weng, Jun-Lin Guan, Xiaolan Deng, Xi Qin, Stefan Hüttelmaier, Chuan He, Hailing Shi, Minjie Wei, Jennifer R. Skibbe, Lei Dong, Huilin Huang, Yueh-Chiang Hu, Ana Mesquita
Publikováno v:
Nature Cell Biology. 22:1288-1288
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c40550155b46cc262897db85e6cc718
https://doi.org/10.1038/s41556-020-00580-y
https://doi.org/10.1038/s41556-020-00580-y
Autor:
Hala Einakat Thomas, Matthew T. Weirauch, Kwangmin Choi, Xiaoting Chen, Nathan Qi, Haruhiko Siomi, Takahisa Nakamura, Esam S. B. Salem, Kazutoshi Murakami, Joonbae Seo, Senad Divanovic, Cai Zhang, Celvie L. Yuan, Vishnupriya J. Borra, Elise Bernhard, Taosheng Huang, Carol A. Mercer, Calvin C. Chan
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
RNA silencing inhibits mRNA translation. While mRNA translation accounts for the majority of cellular energy expenditure, it is unclear if RNA silencing regulates energy homeostasis. Here, we report that hepatic Argonaute 2 (Ago2)-mediated RNA silenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2f0b2483b787cb6f5a4e85c9b67e4bf
https://pubmed.ncbi.nlm.nih.gov/30201950
https://pubmed.ncbi.nlm.nih.gov/30201950
Autor:
Yuka Namiki, Taishi Kimura, Ryan C. Kunz, Gökhan S. Hotamisligil, Cai Zhang, Takahisa Nakamura, Steven P. Gygi, Celvie L. Yuan, Brenna Baccaro
Publikováno v:
Cell Reports, Vol 11, Iss 2, Pp 295-307 (2015)
SummaryAberrant stress and inflammatory responses are key factors in the pathogenesis of obesity and metabolic dysfunction, and the double-stranded RNA-dependent kinase (PKR) has been proposed to play an important role in integrating these pathways.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1662eda4d0b6525de6fde140a2d34d41
Autor:
Celvie L, Yuan, Yueh-Chiang, Hu
Publikováno v:
Advances in experimental medicine and biology. 1016
The use of animal models, particularly rodents, has been immensely important to nearly all aspects of biomedical research, from basic science exploration to translational discoveries into clinical applications. The transgenic core facility that provi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3939d18f783e602cad3e7f182938d41e
https://pubmed.ncbi.nlm.nih.gov/29130154
https://pubmed.ncbi.nlm.nih.gov/29130154
Autor:
Celvie L. Yuan, Yueh-Chiang Hu
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783319639031
The use of animal models, particularly rodents, has been immensely important to nearly all aspects of biomedical research, from basic science exploration to translational discoveries into clinical applications. The transgenic core facility that provi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bba535f6cf7f8ac3e764d3514be40185
https://doi.org/10.1007/978-3-319-63904-8_4
https://doi.org/10.1007/978-3-319-63904-8_4
