A Selective C–C Bond Cleavage Strategy Promoted by Visible Light

Autor: Marcelo Duarte, Igor D. Jurberg, Celso Y. Okada, Victor M. Deflon, Rafael D. C. Gallo, Amanda F. da Silva

Publikováno v: Organic Letters. 23:8916-8920

A new visible-light-promoted reaction between aryldiazoacetates and 1,3-diketones allows good yields and selectivities for C-C bond insertions, leading to the corresponding 1,4-dicarbonyl compounds. This transformation is straightforward and highly p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6416b8767ac6a2b054022a31919cc4d
https://doi.org/10.1021/acs.orglett.1c03406

Visible-Light-Mediated Strategies to Assemble Alkyl 2-Carboxylate-2,3,3-Trisubstituted β-Lactams and 5-Alkoxy-2,2,4-Trisubstituted Furan-3(2H)-ones Using Aryldiazoacetates and Aryldiazoketones

Autor: Rafael D. C. Gallo, Laiéli S. Munaretto, Victor M. Deflon, Igor D. Jurberg, Celso Y. Okada, Caio Y. dos Santos

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Two new visible-light-mediated strategies are described starting from aryldiazoacetates. The first approach describes their reaction with azides to afford the corresponding imines, and then reaction with aryldiazoketones produces alkyl 2-carboxylate-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b6310aa79b929d673336c9726dbc3b2
https://pubmed.ncbi.nlm.nih.gov/34797682

Blue light-promoted N–H insertion of amides, isatins, sulfonamides and imides into aryldiazoacetates: Synthesis of unnatural α-aryl amino acid derivatives

Autor: Igor D. Jurberg, Caio Y. dos Santos, Celso Y. Okada

Publikováno v: Tetrahedron. 76:131316

A photochemical protocol using blue light allows the N–H insertion of amides, isatins, sulfonamides and imides into aryldiazoacetates to afford the corresponding α-amino esters. This method is experimentally simple, inexpensive and tolerates numer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::35f40b2bbac49cea5b119626399e280f
https://doi.org/10.1016/j.tet.2020.131316