Zobrazeno 1 - 10
of 1 871
pro vyhledávání: '"Cellular signaling"'
Publikováno v:
Diabetes, Metabolic Syndrome and Obesity, Vol Volume 17, Pp 3151-3161 (2024)
Xiuju Guan,1 Yue Liu,2 Yajuan An,1 Xinshuang Wang,1 Liping Wei,2 Xin Qi2 1School of Graduate Studies, Tianjin University of Traditional Chinese Medicine, Tianjin, People’s Republic of China; 2Department of Cardiology, Tianjin Union Medical Center,
Externí odkaz:
https://doaj.org/article/0fff6bf9f05840b3bfc7a7ae8f61cff6
Autor:
Liu Jianwei, Gu Jianguo
Publikováno v:
Acta Biochimica et Biophysica Sinica, Vol 56, Pp 1199-1207 (2024)
FMS-like tyrosine kinase 3 (FLT3) is a receptor tyrosine kinase expressed in hematopoietic cells. Internal-tandem duplication domain (ITD) mutation and tyrosine kinase domain (TKD) mutation are the two most common mutations in acute myeloid leukemia
Externí odkaz:
https://doaj.org/article/a040752fc06f4781813d074953acfa5a
Autor:
Yuetong Wang, Qiaoming Li, Yahui Ding, Chenfei Luo, Jun Yang, Na Wang, Ning Jiang, Tiange Yao, Guohao Wang, Guoming Shi, Steven X. Hou
Publikováno v:
Advanced Science, Vol 11, Iss 39, Pp n/a-n/a (2024)
Abstract The small G protein Arf1 has been identified as playing a selective role in supporting cancer stem cells (CSCs), making it an attractive target for cancer therapy. However, the current Arf1 inhibitors have limited translational potential due
Externí odkaz:
https://doaj.org/article/3123fbd059c74f3b8874b217b59b7168
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Externí odkaz:
https://doaj.org/article/e09612daaa0b426caa5b9ecce365beb2
Autor:
Youngjae Ryu, Aboubacar Wague, Xuhui Liu, Brian T. Feeley, Adam R. Ferguson, Kazuhito Morioka
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Mechanical stimuli, such as stretch, shear stress, or compression, activate a range of biomolecular responses through cellular mechanotransduction. In the nervous system, studies on mechanical stress have highlighted key pathophysiological mechanisms
Externí odkaz:
https://doaj.org/article/e41a6032422d4663a32487440f52a3b6
Publikováno v:
Journal of King Saud University: Science, Vol 36, Iss 9, Pp 103372- (2024)
The enzyme protein kinase G1 (PRKG1) plays a crucial role in cellular signaling pathways such as smooth muscle relaxation, neuronal signaling, and platelet aggregation. The dysregulation of PRKG1 leads to different diseases, making it a promising dru
Externí odkaz:
https://doaj.org/article/a434a82542fe48c99d130e5a5944aec4
Autor:
Hannah Zuppe, Erin Reed
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Dementia is an umbrella term used to describe deterioration of cognitive function. It is the seventh leading cause of death and is one of the major causes of dependence among older people globally. Alzheimer’s Disease (AD) contributes to approximat
Externí odkaz:
https://doaj.org/article/2a2e3643be094dd2872106921ac532ab
Autor:
Kathryn A. F. Pennel, Phimmada Hatthakarnkul, Colin S. Wood, Guang-Yu Lian, Sara S. F. Al-Badran, Jean A. Quinn, Assya Legrini, Jitwadee Inthagard, Peter G. Alexander, Hester van Wyk, Ahmad Kurniawan, Umar Hashmi, Michael A. Gillespie, Megan Mills, Aula Ammar, Jennifer Hay, Ditte Andersen, Colin Nixon, Selma Rebus, David K. Chang, Caroline Kelly, Andrea Harkin, Janet Graham, David Church, Ian Tomlinson, Mark Saunders, Tim Iveson, Tamsin R. M. Lannagan, Rene Jackstadt, Noori Maka, Paul G. Horgan, Campbell S. D. Roxburgh, Owen J. Sansom, Donald C. McMillan, Colin W. Steele, Nigel B. Jamieson, James H. Park, Antonia K. Roseweir, Joanne Edwards
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-20 (2024)
Abstract Colorectal cancer (CRC) is a heterogenous malignancy underpinned by dysregulation of cellular signaling pathways. Previous literature has implicated aberrant JAK/STAT3 signal transduction in the development and progression of solid tumors. I
Externí odkaz:
https://doaj.org/article/3b63169b435447a19a5fb490ee037279
Autor:
Michał Rurek
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
The rapid development of the COVID-19 pandemic resulted in a closer analysis of cell functioning during β-coronavirus infection. This review will describe evidence for COVID-19 as a syndrome with a strong, albeit still underestimated, mitochondrial
Externí odkaz:
https://doaj.org/article/c1ee35356f2146f199494f33ada2ee39