Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Cellular quiescence"'
Publikováno v:
Biomolecules, Vol 13, Iss 11, p 1662 (2023)
(1) Background: The LEO1 (Left open reading frame 1) protein is a conserved subunit of the PAF1C complex (RNA polymerase II-associated factor 1 complex). PAF1C has well-established mechanistic functions in elongation of transcription and RNA processi
Externí odkaz:
https://doaj.org/article/f1e28d7437774fccb6b62f7be2070917
Autor:
Trevor G. Shepherd, Frederick A. Dick
Publikováno v:
Cell Division, Vol 17, Iss 1, Pp 1-11 (2022)
Abstract In cancer, dormancy refers to a clinical state in which microscopic residual disease becomes non-proliferative and is largely refractory to chemotherapy. Dormancy was first described in breast cancer where disease can remain undetected for d
Externí odkaz:
https://doaj.org/article/c63c33b94dcf4743a7ad5ec8b4ab60d4
Autor:
Karin Ortmayr, Mattia Zampieri
Publikováno v:
Molecular Systems Biology, Vol 18, Iss 9, Pp n/a-n/a (2022)
Abstract Quiescent cancer cells are rare nondiving cells with the unique ability to evade chemotherapies and resume cell division after treatment. Despite the associated risk of cancer recurrence, how cells can reversibly switch between rapid prolife
Externí odkaz:
https://doaj.org/article/fcae0e5559a94c6d9da8b4bf5c4a83bf
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The balance between cell quiescence and proliferation is fundamental to tissue physiology and homeostasis. Recent studies have shown that quiescence is not a passive and homogeneous state but actively maintained and heterogeneous. These cellular char
Externí odkaz:
https://doaj.org/article/df07caa816c5433c9b5f6fe9ec4c3cbc
Autor:
Eriko Oya, Mickaël Durand-Dubief, Adiel Cohen, Vladimir Maksimov, Catherine Schurra, Jun-ichi Nakayama, Ronit Weisman, Benoit Arcangioli, Karl Ekwall
Publikováno v:
Epigenetics & Chromatin, Vol 12, Iss 1, Pp 1-12 (2019)
Abstract Background Cellular quiescence is a reversible differentiation state during which cells modify their gene expression program to inhibit metabolic functions and adapt to a new cellular environment. The epigenetic changes accompanying these al
Externí odkaz:
https://doaj.org/article/4ae462d8821e495d99787821827ef7e3
Akademický článek
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Autor:
Jungeun Sarah Kwon, Nicholas J. Everetts, Xia Wang, Weikang Wang, Kimiko Della Croce, Jianhua Xing, Guang Yao
Publikováno v:
Cell Reports, Vol 20, Iss 13, Pp 3223-3235 (2017)
Quiescence is a non-proliferative cellular state that is critical to tissue repair and regeneration. Although often described as the G0 phase, quiescence is not a single homogeneous state. As cells remain quiescent for longer durations, they move pro
Externí odkaz:
https://doaj.org/article/384d8d4c54f2412e9904866d6c608482
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 117, Iss , Pp - (2019)
The inhibitory roles of limonin have been revealed in various tumors. However, the roles and related mechanism of limonin in hepatocellular carcinoma (HCC) progression are still confused. Here, we collected non-adherent spheroids formed by HCC cells
Externí odkaz:
https://doaj.org/article/760a169ff07b4384b0b9f0bbc28d2fdc
Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
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Autor:
Valeriia Gulaia, Vadim Kumeiko, Nikita Shved, Eduardas Cicinskas, Stanislav Rybtsov, Alexey Ruzov, Alexander Kagansky
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Cellular quiescence is a reversible, non-cycling state controlled by epigenetic, transcriptional and niche-associated molecular factors. Quiescence is a condition where molecular signaling pathways maintain the poised cell-cycle state whilst enabling
Externí odkaz:
https://doaj.org/article/4a0a51a062c64132b4eaed349b4376b9