Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Cellular programming"'
Autor:
Rui-lin Li, Sheng Kang
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-11 (2024)
Abstract External constraints, such as development, disease, and environment, can induce changes in epigenomic patterns that may profoundly impact the health trajectory of fetuses and neonates into adulthood, influencing conditions like obesity. Epig
Externí odkaz:
https://doaj.org/article/ec6c65ac941240d99edf43e325b84bbd
Akademický článek
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Publikováno v:
Nanoscale. 13:16834-16846
DNA-based nanotechnology has evolved into an autonomous, highly innovative, and dynamic field of research at the nexus of supramolecular chemistry, nanotechnology, materials science, and biotechnology. DNA-based materials, including origami nanodevic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ce07debfe42ac300dfccc110b3339d1
https://doi.org/10.1039/d1nr04475c
https://doi.org/10.1039/d1nr04475c
Autor:
Rahi Patel, Wayne O. Miles, R. Ranjith Kumar, Wilhelm Haas, Brandon Nicolay, Chenyu Lin, Benedikt Obermayer, Robert Morris, Capucine Van Rechem, Myriam Boukhali, Emanuel Wyler, Nicholas J. Dyson, Swetha Rajasekaran, Jessica B. Rakijas, Eshan Khan, Christine Vogel, Markus Landthaler, Jayashree Balasubramanyam, Jalal K. Siddiqui, Sailaja Elchuri
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-1 (2021)
Communications Biology, Vol 4, Iss 1, Pp 1-1 (2021)
Inactivation of RB is one of the hallmarks of cancer, however gaps remain in our understanding of how RB-loss changes human cells. Here we show that pRB-depletion results in cellular reprogramming, we quantitatively measured how RB-depletion altered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0f73bf244aedeae715594af226b9f22
http://europepmc.org/articles/PMC8484276
http://europepmc.org/articles/PMC8484276
Autor:
Wayne O. Miles, Capucine Van Rechem, Swetha Rajasekaran, Jalal K. Siddiqui, Sailaja Elchuri, R. Ranjith Kumar, Christine Vogel, Jayashree Balasubramanyam, Robert Morris, Wilhelm Haas, Rahi Patel, Jessica B. Rakijas, Markus Landthaler, Myriam Boukhali, Benedikt Obermayer, Eshan Khan, Emanuel Wyler, Nicholas J. Dyson, Brandon Nicolay, Chenyu Lin
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Communications Biology
Communications Biology
Inactivation of RB is one of the hallmarks of cancer, however gaps remain in our understanding of how RB-loss changes human cells. Here we show that pRB-depletion results in cellular reprogramming, we quantitatively measured how RB-depletion altered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdbad3217b9b0a54197007fc429cb148
http://edoc.mdc-berlin.de/20853/1/20853oa.pdf
http://edoc.mdc-berlin.de/20853/1/20853oa.pdf
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Temporal modulation of the expression of multiple genes underlies complex complex biological phenomena. However, there are few scalable and generalizable gene circuit architectures for the programming of sequential genetic perturbations. Here, we des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb32fc2c783fbe0f20eade633804afd1
https://doi.org/10.1038/s41467-021-22978-4
https://doi.org/10.1038/s41467-021-22978-4
Autor:
Kenneth A. Dawson, Yan Yan
Nanoscale objects are processed by living organisms using highly evolved and sophisticated endogenous cellular networks, specifically designed to manage objects of this size. While these processes potentially allow nanostructures unique access to and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca5647bd7f0c63d9d5b84a93c447189d
Autor:
Daniel A. Dumesic, Lucia Carbone, Mariam Okhovat, Phillip A. Dumesic, Catherine T. Pham, Feiyang Ma, Xiangming Ding, Xin-Min Li, Marco Morselli, Matteo Pellegrini, Gregorio D. Chazenbalk, Tristan Grogan, Kevin J. Williams, Smriti Sanchita, Brett Davis, Karen L. Leung
Publikováno v:
Clinical epigenetics, vol 12, iss 1
Clinical Epigenetics
Clinical Epigenetics
Background Normal-weight polycystic ovary syndrome (PCOS) women exhibit adipose resistance in vivo accompanied by enhanced subcutaneous (SC) abdominal adipose stem cell (ASC) development to adipocytes with accelerated lipid accumulation per cell in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::244d9a220a6975f8635c815cb538a35b
https://escholarship.org/uc/item/2pb2p62c
https://escholarship.org/uc/item/2pb2p62c
Publikováno v:
Molecular Cell. 76:1-3
High plasticity to utilize different nutrients to adapt metabolic stress is one of the hallmarks for cancer cells. However, the underlying mechanisms by which cancer cells reprogram metabolic machinery in response to metabolic stress remain largely u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e692f119bab965b499ff9473b818be86
https://doi.org/10.1016/j.molcel.2019.09.002
https://doi.org/10.1016/j.molcel.2019.09.002