Zobrazeno 1 - 10
of 641
pro vyhledávání: '"Cellular origin"'
Autor:
Shibo Zhang, Yi Li, Meihan Chu, Kexin Yu, Yangguang Su, Kun Zhou, Ying Wang, Xin Zhang, Xiujie Chen
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Hepatocellular carcinoma metastasis occurs mainly in the portal vein and lymph node metastasis, and is the main cause of patient death. However, the cellular origins and driving mechanisms of hepatocellular carcinoma metastasis have not been
Externí odkaz:
https://doaj.org/article/de279ef353dd4d86acfa21f5191a2a1e
Autor:
Akira Nishijima, Katsutoshi Oda, Kosei Hasegawa, Takahiro Koso, Kayo Asada, Yuji Ikeda, Ayumi Taguchi, Daichi Maeda, Genta Nagae, Shingo Tsuji, Kenji Tatsuno, Yuriko Uehara, Akira Kurosaki, Sho Sato, Michihiro Tanikawa, Kenbun Sone, Mayuyo Mori, Masako Ikemura, Keiichi Fujiwara, Tetsuo Ushiku, Yutaka Osuga, Hiroyuki Aburatani
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract The cellular origin of clear cell ovarian carcinoma (CCOC), a major histological subtype of ovarian carcinoma remains elusive. Here, we explored the candidate cellular origin and identify molecular subtypes using integrated genomic/epigenomi
Externí odkaz:
https://doaj.org/article/a2d3c4a31a7e42538b3288347db60cbd
Publikováno v:
Cancer Biology & Therapy, Vol 25, Iss 1 (2024)
Chronic lymphocytic leukemia (CLL) and multiple myeloma (MM) are hematological disorders affecting B cells. The clonal relationship between CLL and MM has not always been clarified, although this information is critical to understanding its pathogene
Externí odkaz:
https://doaj.org/article/15984173ec3b4ece98c09544e822e93a
Autor:
Kiyoshi Saeki, Ian S. Wood, Wei Chuan Kevin Wang, Shilpa Patil, Yanping Sun, David F. Schaeffer, Gloria H. Su, Janel L. Kopp
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 18, Iss 5, Pp 101387- (2024)
Background & Aims: Pancreatic ductal adenocarcinoma can develop from precursor lesions, including pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasm (IPMN). Previous studies indicated that loss of Acvr1b accelerates the
Externí odkaz:
https://doaj.org/article/c27ef1153cab422c94a5c4539953f4d7
Akademický článek
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Akademický článek
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Autor:
Yuchen Li, Ye Li, Shulin Yu, Ling Qian, Kun Chen, Hongyan Lai, Hena Zhang, Yan Li, Yalei Zhang, Sijia Gu, Zhiqiang Meng, Shenglin Huang, Peng Wang
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 26, Iss , Pp 488-501 (2021)
Identification of clinically applicable molecular subtypes of pancreatic ductal adenocarcinoma (PDAC) is crucial to improving patient outcomes. However, the traditional tissue-dependent transcriptional subtyping strategies are invasive and not amenab
Externí odkaz:
https://doaj.org/article/118721b6ec3c44b18fa528378701db65
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 2851-2859 (2020)
Extracellular vesicles (EVs) are complex ecosystems that can be derived from all body cells and circulated in the body fluids. Characterizing the tissue-cellular source contributing to circulating EVs provides biological information about the cell or
Externí odkaz:
https://doaj.org/article/66166cd6fc1a4810b0c379fda7acf0fa
Autor:
Ziyu Li, Shuisheng Yu, Xuyang Hu, Yiteng Li, Xingyu You, Dasheng Tian, Li Cheng, Meige Zheng, Juehua Jing
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
The failure of axonal regeneration after spinal cord injury (SCI) results in permanent loss of sensorimotor function. The persistent presence of scar tissue, mainly fibrotic scar and astrocytic scar, is a critical cause of axonal regeneration failure
Externí odkaz:
https://doaj.org/article/de6abaf9990540f3b7c4f84ca1b427b6
Autor:
Ka-Cheuk Liu, Alethia Villasenor, Maria Bertuzzi, Nicole Schmitner, Niki Radros, Linn Rautio, Kenny Mattonet, Ryota L Matsuoka, Sven Reischauer, Didier YR Stainier, Olov Andersson
Publikováno v:
eLife, Vol 10 (2021)
To investigate the role of the vasculature in pancreatic β-cell regeneration, we crossed a zebrafish β-cell ablation model into the avascular npas4l mutant (i.e. cloche). Surprisingly, β-cell regeneration increased markedly in npas4l mutants owing
Externí odkaz:
https://doaj.org/article/5fcefc8ad85f405783b16d404e47a553