Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Cellular ion homeostasis"'
RETRACTED: Liposomal valinomycin mediated cellular K+ leak promoting apoptosis of liver cancer cells
Autor:
Qian-Wen Zhang, Xing-Hua Xia, Mirza Muhammad Faran Ashraf Baig, Tian-Qi Zhang, Xiang Qin, Ting-Ting Zhai
Publikováno v:
Journal of Controlled Release. 337:317-328
Most cancer therapies are suffering from side effects to varying degrees, which might compromise the body functions and long-term health of patients. Balancing treatment efficacy and side effects has become a priority. Inspired by the concept that ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccb5dc5070c60a27093ebac98fc7000a
https://doi.org/10.1016/j.jconrel.2021.07.037
https://doi.org/10.1016/j.jconrel.2021.07.037
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Na+/H+ antiporters comprise a family of membrane proteins evolutionarily conserved in all kingdoms of life that are essential in cellular ion homeostasis. While several human homologues have long been drug targets, NhaA of Escherichia coli has become
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e512e08f808f76bc33410395176bb3f7
https://doaj.org/article/721bce5313a84b5289f7dd4b58c7b205
https://doaj.org/article/721bce5313a84b5289f7dd4b58c7b205
Publikováno v:
Autophagy
Lysosomes serve as cellular degradation and signalling centres that coordinate metabolism in response to intracellular cues and extracellular signals. Lysosomal capacity is adapted to cellular needs by transcription factors, such as TFEB and TFE3, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d35bddbfb30323b37d3cb8b875656b7
https://doi.org/10.1038/s41556-020-0535-7
https://doi.org/10.1038/s41556-020-0535-7
Publikováno v:
Journal of the American Chemical Society. 142:10769-10779
Molecules that are capable of disrupting cellular ion homeostasis offer unique opportunities to treat cancer. However, previously reported synthetic ion transporters showed limited value, as promiscuous ionic disruption caused toxicity to both health
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a510f01eafd7d920f632558f663919f
https://doi.org/10.1021/jacs.0c02134
https://doi.org/10.1021/jacs.0c02134
Autor:
Liming Xiong, Yiting Shi, Yan Guo, Jijang Li, Yu Wang, Guohua Xu, Feng Qin, Peng Yun Wang, Jian-Kang Zhu, Dai-Yin Chao, Yongqing Yang, Shuhua Yang, Luis Herrera-Estrella, Huazhong Shi, Jingrui Li, Zhizhong Gong, Yanglin Ding
Publikováno v:
Science China Life Sciences. 63:635-674
Abiotic stresses and soil nutrient limitations are major environmental conditions that reduce plant growth, productivity and quality. Plants have evolved mechanisms to perceive these environmental challenges, transmit the stress signals within cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3fb828bed3db9836f413f591e6e6af5
https://doi.org/10.1007/s11427-020-1683-x
https://doi.org/10.1007/s11427-020-1683-x
Autor:
Rui-Yu Cheng, Xiang-Yi Zhang, Xiao Fu, Yan-Ling Lan, Chang-Bao Wang, Xing-Jin He, Deng-Feng Xie, Megan Price
Publikováno v:
Frontiers in Plant Science, Vol 12 (2021)
Frontiers in Plant Science
Frontiers in Plant Science
The karst environment is characterized by low soil water content, periodic water deficiency, and poor nutrient availability, which provides an ideal natural laboratory for studying the adaptive evolution of its inhabitants. However, how species adapt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bb2452955a56aab5dcd625a48051c3c
https://www.frontiersin.org/articles/10.3389/fpls.2021.667988/full
https://www.frontiersin.org/articles/10.3389/fpls.2021.667988/full
Publikováno v:
Chinese Chemical Letters. 31:479-481
Ionophore can prominently improve the ion permeability of cell membrane and disrupt cellular ion homeostasis. Most studies regarding ionophore facilitating ion transmembrane transport focus on artificial liquid-liquid interfaces, which have large dif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7a1eda6e49b95ce75a51aef3b1edb7e
https://doi.org/10.1016/j.cclet.2019.08.009
https://doi.org/10.1016/j.cclet.2019.08.009
Publikováno v:
Journal of Experimental Botany
Plant heat shock transcription factors (HSFs) are involved in heat and other abiotic stress responses. However, their functions in salt tolerance are little known. In this study, we characterized the function of a HSF from Arabidopsis, AtHSFA7b, in s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bd5247bddcef26314b6d3ca7670b16f
https://doi.org/10.1093/jxb/erz261
https://doi.org/10.1093/jxb/erz261
Autor:
Hyoung Youn Lee, Yong Hun Jung, Jin Woong Kim, Byung Kook Lee, Tag Heo, Kyung Woon Jeung, Yong Il Min, Najmiddin Mamadjonov, Chun Song Youn
Publikováno v:
Resuscitation. 137:116-123
Several studies reported that disturbances in cellular ion homeostasis occur following ischaemia, the magnitude of which was proportional to illness severity. The changes in serum electrolyte levels following ischaemia were minor compared with the ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fc62a2baf75700e8cf794745ec8a72f
https://doi.org/10.1016/j.resuscitation.2019.02.020
https://doi.org/10.1016/j.resuscitation.2019.02.020
Autor:
Balk, Samuel D., Polimeni, Philip I., Hoon, Baldev Singh, LeStourgeon, Dana N., Mitchell, Richard S.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1979 Aug 01. 76(8), 3913-3916.
Externí odkaz:
https://www.jstor.org/stable/69737