Zobrazeno 1 - 10
of 1 686
pro vyhledávání: '"Cellular immunotherapy"'
Publikováno v:
Bioactive Materials, Vol 42, Iss , Pp 379-403 (2024)
Adoptive immunotherapy, notably involving chimeric antigen receptor (CAR)-T cells, has obtained Food and Drug Administration (FDA) approval as a treatment for various hematological malignancies, demonstrating promising preclinical efficacy against ca
Externí odkaz:
https://doaj.org/article/8f42f26ac76442319ad7c9bcdfd7c18a
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 12323-12342 (2024)
Jiale Wu,1,2 Kaihong Shi,1,2 Wei Chao,1,2 Zeyu Qin,1,2 Youhui Hu,1,2 Yihua Yang,1,2 Yuan He,1,2 Yabing Hua,1,2 Ziming Zhao1,2 1Department of Pharmacy, Xuzhou Medical University, Xuzhou, People’s Republic of China; 2Jiangsu Key Laboratory of New Dru
Externí odkaz:
https://doaj.org/article/b6abb4012b4d4a8cbfcf009ac0fe6a0f
Autor:
Kopmar NE, Cassaday RD
Publikováno v:
Cancer Management and Research, Vol Volume 16, Pp 1587-1596 (2024)
Noam E Kopmar,1,2 Ryan D Cassaday1,2 1Division of Hematology and Oncology, Department of Medicine, University of Washington School of Medicine, Seattle, WA, USA; 2Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA, USACorresponden
Externí odkaz:
https://doaj.org/article/39b645b6b6ba4b0183e72281f86633ab
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Background Chimeric antigen receptor (CAR)-T therapy has emerged as a promising treatment for hematologic malignancies. However, cytopenia remains one of the most frequent and challenging adverse effects of this therapy. Methods We conducted
Externí odkaz:
https://doaj.org/article/d3c85e66332f47c3b2f0ba5e50178e89
Publikováno v:
Zhongliu Fangzhi Yanjiu, Vol 51, Iss 8, Pp 648-654 (2024)
Tumor immunotherapy occupies a pivotal position in the field of hematological malignancies. Chimeric antigen receptor (CAR) T-cell therapy has established a new therapeutic pattern for hematological immunotherapy and achieved satisfactory clinical re
Externí odkaz:
https://doaj.org/article/356ab3a80d3b45df983e66a0bbd94215
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-10 (2024)
Abstract Background This study details a case of a patient with advanced lung adenocarcinoma harboring an exon 19 deletion in the EGFR gene. Method A 46-year-old female patient was diagnosed with stage IVb left lung adenocarcinoma, with multiple bone
Externí odkaz:
https://doaj.org/article/80d5d3af63ff41a699171a594dbaef19
Publikováno v:
BMC Gastroenterology, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Objective To construct chimeric antigen receptor (CAR)-T cells targeting epithelial cell adhesion molecule (EpCAM) antigen (anti-EpCAM-CAR-T). Methods A third-generation CAR-T cell construct used a single-chain variable fragment derived from
Externí odkaz:
https://doaj.org/article/b4f25a948a394e4385a4b8e4413de673
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)
Cellular immunotherapy has shown considerable potential for the treatment of primary liver cancer (PLC), particularly hepatocellular carcinoma (HCC), although it is in the early stages of development. This study used bibliometric methods to delineate
Externí odkaz:
https://doaj.org/article/0dcd9b79b86d4dba8b535658a010d8ee
Autor:
Tatyana Matikhina, Cyrille J. Cohen
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionTGFβ is a major immunoinhibitory factor present in the microenvironment of solid tumors. Various cancer types acquire the ability to overexpress TGFβ to escape immune response. Specifically, TGFβ dampens cytotoxic T cell activity, and
Externí odkaz:
https://doaj.org/article/2f3cd82e18494d0b8c66415cf2725844
Autor:
Jingge Lian, Meng Li, Meng Duan, Yaqian Sun, Zilin Wang, Xinyu Guo, Jingchao Li, Guo Gao, Kangan Li
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Adoptive cellular immunotherapy as a promising and alternative cancer therapy platform is critical for future clinical applications. Natural killer (NK) cells have attracted attention as an important type of innate immune regulatory cells th
Externí odkaz:
https://doaj.org/article/b96ea4008ce04790ba1b26cd4e24fa4b