Zobrazeno 1 - 10
of 574
pro vyhledávání: '"Cellular Potts model"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
3D cell culture models replicate tissue complexity and aim to study cellular interactions and responses in a more physiologically relevant environment compared to traditional 2D cultures. However, the spherical structure of these models makes it diff
Externí odkaz:
https://doaj.org/article/0ce9f064189748cba2871c36f5e251c2
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
3D multicellular self-organized cluster models, e.g., organoids are promising tools for developing new therapeutic modalities including gene and cell therapies, pharmacological mechanistic and screening assays. Various applications of these models ha
Externí odkaz:
https://doaj.org/article/47a0780eb61f462e948e7f8954fc5db2
Publikováno v:
Applied Sciences, Vol 14, Iss 16, p 7028 (2024)
Power consumption is a significant challenge in the sustainability of computational science. The growing energy demands of increasingly complex simulations and algorithms lead to substantial resource use, which conflicts with global sustainability go
Externí odkaz:
https://doaj.org/article/009e1b99642440e987003d420e13fab6
Autor:
Rose Una, Tilmann Glimm
Publikováno v:
PeerJ, Vol 12, p e16974 (2024)
We investigate the behavior of systems of cells with intracellular molecular oscillators (“clocks”) where cell-cell adhesion is mediated by differences in clock phase between neighbors. This is motivated by phenomena in developmental biology and
Externí odkaz:
https://doaj.org/article/b523c77d9170490dab585826468c02e3
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Epithelial-mesenchymal transition (EMT) and immune resistance mediated by Programmed Death-Ligand 1 (PD-L1) upregulation are established drivers of tumor progression. Their bi-directional crosstalk has been proposed to facilitate tumor immunoevasion,
Externí odkaz:
https://doaj.org/article/cc17b7a0b83a4c5bbcf5d006a6bb64cc
Publikováno v:
Frontiers in Applied Mathematics and Statistics, Vol 9 (2023)
Collective cell migration is an important process during biological development and tissue repair but may turn malignant during tumor invasion. Mathematical and computational models are essential to unravel the mechanisms of self-organization that un
Externí odkaz:
https://doaj.org/article/98b1a15a6f93496abc24ef3f5ab66e40
Publikováno v:
Biophysics and Physicobiology, Vol 20 (2023)
To computationally investigate the recent experimental finding such that extracellular ATP release caused by exogeneous mechanical forces promote wound closure, we introduce a mathematical model, the Cellular Potts Model (CPM), which is a popular dis
Externí odkaz:
https://doaj.org/article/66d08e93380d4893bfc49b5fc3defe4c
Akademický článek
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Akademický článek
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Publikováno v:
Life, Vol 13, Iss 2, p 427 (2023)
Mathematical and computational models are used to describe biomechanical processes in multicellular systems. Here, we develop a model to analyse how two types of epithelial cell layers interact during tissue invasion depending on their cellular prope
Externí odkaz:
https://doaj.org/article/f98ca5cee51648c49cf4ff17e10632ec