Zobrazeno 1 - 10
of 501
pro vyhledávání: '"Cellular Assay"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 3654 (2024)
Type 2 diabetes mellitus (T2DM) is marked by persistent hyperglycemia, insulin resistance, and pancreatic β-cell dysfunction, imposing substantial health burdens and elevating the risk of systemic complications and cardiovascular diseases. While the
Externí odkaz:
https://doaj.org/article/c1df91ae44bd4bc28b8b7a09cba51969
Autor:
Aixiao Li, Ahmed Bouhss, Marie-Jeanne Clément, Cyril Bauvais, J. Paul Taylor, Guillaume Bollot, David Pastré
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
In recent years, RNA has gained traction both as a therapeutic molecule and as a therapeutic target in several human pathologies. In this review, we consider the approach of targeting RNA using small molecules for both research and therapeutic purpos
Externí odkaz:
https://doaj.org/article/22c47e5584934302a02e842601707265
Autor:
Dawid Głów, Simon Meyer, Irene García Roldán, Lara Marie Akingunsade, Kristoffer Riecken, Boris Fehse
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 22, Iss , Pp 249-262 (2021)
Since the introduction of clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9), genome editing has been broadly applied in basic research and applied biotechnology, whereas translation into clinical te
Externí odkaz:
https://doaj.org/article/6f33396e84f94dfc9ac886fa0a5d9a8b
Autor:
Huifen Ding, Sunil George, Xiaoyan Iris Leng, Michael Ihnat, Jian-Xing Ma, Guochun Jiang, David Margolis, Julie Dumond, Yuanyuan Zhang
Publikováno v:
Materials Today Advances, Vol 15, Iss , Pp 100261- (2022)
Despite being widely applied in drug development, existing in vitro 2D cell-based models are not suitable to assess chronic mitochondrial toxicity. A novel in vitro assay system mimicking in vivo micro-environment for this purpose is urgently needed.
Externí odkaz:
https://doaj.org/article/1b533cd54a144ea1a07e7619b2345fac
Akademický článek
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Publikováno v:
Nutrients, Vol 14, Iss 19, p 4141 (2022)
Vitamins are known to generate bitterness, which may contribute to an off-taste or aftertaste for some nutritional supplements. This negative sensation can lead to a reduction in their consumption. Little is known about the bitter taste threshold and
Externí odkaz:
https://doaj.org/article/029f45bab8b849809b87ab1544b634d2
Autor:
Marcel Jaron, Michael Lehky, Marta Zarà, Chris Nicole Zaydowicz, Aidin Lak, Rico Ballmann, Philip Alexander Heine, Esther Veronika Wenzel, Kai-Thomas Schneider, Federico Bertoglio, Susanne Kempter, Reinhard Wolfgang Köster, Silvia Stella Barbieri, Joop van den Heuvel, Michael Hust, Stefan Dübel, Maren Schubert
Publikováno v:
Viruses, Vol 14, Iss 10, p 2087 (2022)
Virus-like particles (VLPs) resemble authentic virus while not containing any genomic information. Here, we present a fast and powerful method for the production of SARS-CoV-2 VLP in insect cells and the application of these VLPs to evaluate the inhi
Externí odkaz:
https://doaj.org/article/059ba81e8dae4b76b6f823fda47e7e79
Autor:
Zand Z, Khaki PA, Salihi A, Sharifi M, Qadir Nanakali NM, Alasady AAB, Aziz FM, Shahpasand K, Hasan A, Falahati M
Publikováno v:
International Journal of Nanomedicine, Vol Volume 14, Pp 6989-7000 (2019)
Zahra Zand,1,* Pegah Afarinesh Khaki,2,* Abbas Salihi,3,4 Majid Sharifi,5,6 Nadir Mustafa Qadir Nanakali,7,8 Asaad AB Alasady,9 Falah Mohammad Aziz,3 Koorosh Shahpasand,10 Anwarul Hasan,11,12 Mojtaba Falahati51Department of Biochemistry and Biophysic
Externí odkaz:
https://doaj.org/article/54ddc45677384dcfbb01214829ef23ca
Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
Autor:
Irene García Roldán, Kristoffer Riecken, Simon Meyer, Dawid Głów, Lara Marie Akingunsade, Boris Fehse
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 22, Iss, Pp 249-262 (2021)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
Since the introduction of clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9), genome editing has been broadly applied in basic research and applied biotechnology, whereas translation into clinical te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44b72aaecc21d909ffa627acfdd456a5
https://doi.org/10.1016/j.omtm.2021.07.004
https://doi.org/10.1016/j.omtm.2021.07.004