The Extracellular, Cellular, and Nuclear Stiffness, a Trinity in the Cancer Resistome—A Review

Autor: Sara Sofia Deville, Nils Cordes

Publikováno v: Frontiers in Oncology, Vol 9 (2019)

Alterations in mechano-physiological properties of a tissue instigate cancer burdens in parallel to common genetic and epigenetic alterations. The chronological and mechanistic interrelation between the various extra- and intracellular aspects remain

Externí odkaz: https://doaj.org/article/88e737a5185b4765acbcb35d5a4751d7

A computational framework for modeling cell���matrix interactions in soft biological tissues

Autor: Roland C. Aydin, Maximilian J. Grill, Iman Davoodi Kermani, Wolfgang A. Wall, Jay D. Humphrey, Jonas F. Eichinger, Christian J. Cyron

Publikováno v: Biomechanics and Modeling in Mechanobiology
Biomechanics and Modeling in Mechanobiology 20 (5): 1851-1870 (2021-10-01)
Eichinger, J.F.; Grill, M.J.; Kermani, I.D.; Aydin, R.C.; Wall, W.A.; Humphrey, J.D.; Cyron, C.J.: A computational framework for modeling cell–matrix interactions in soft biological tissues. In: Biomechanics and Modeling in Mechanobiology. Vol. 20 (2021) 1851-1870. (DOI: /10.1007/s10237-021-01480-2)

Living soft tissues appear to promote the development and maintenance of a preferred mechanical state within a defined tolerance around a so-called set point. This phenomenon is often referred to as mechanical homeostasis. In contradiction to the pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bfef8371fc88e78bde357607c6b1f3a

Meniscus Matrix Remodeling in Response to Compressive Forces in Dogs

Autor: Giuseppe M. Peretti, Alessia Di Giancamillo, Laura Mangiavini, Liliana Maria Carnevale, Mauro Di Giancamillo, M Agnoletto, Luca Maria Sconfienza, Maria Cristina Veronesi, Federica Boschetti, Silvia Modina, Umberto Polito

Publikováno v: Cells, Vol 9, Iss 2, p 265 (2020)
Cells
Volume 9
Issue 2

Joint motion and postnatal stress of weight bearing are the principal factors that determine the phenotypical and architectural changes that characterize the maturation process of the meniscus. In this study, the effect of compressive forces on the m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f783b16c2784264b2390a4e6d9a97863
https://www.mdpi.com/2073-4409/9/2/265

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Establishment of Sandwich Cultures of Primary Human Hepatocytes

Autor: Eva Gijbels, Mathieu Vinken, Tamara Vanhaecke

Publikováno v: Methods in Molecular Biology ISBN: 9781493994199

Primary hepatocytes and their adherent cultures are still considered as the golden standard in the field of liver-based in vitro modeling. However, they cope with progressive deterioration of their in vivo-like morphological and functional phenotype.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5b9643e6050ba02b89edf5dba0a615d
https://doi.org/10.1007/978-1-4939-9420-5_21