Zobrazeno 1 - 10
of 444
pro vyhledávání: '"Cell-cycle inhibitors"'
Autor:
Erick Damián Castañeda-Reyes, Alejandro Gonzalez-Almazán, Alán Lubbert-Licón, Najwa Farhana Yahya, Elvira Gonzalez de Mejia
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Melanoma is the most aggressive type of skin cancer and can metastasize during primary tumor formation. This research aimed to determine the relationship between the prevention of melanoma development in a mouse model treated with liposomes
Externí odkaz:
https://doaj.org/article/fc5a2e18921342b387218b2b4ac55bd8
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
BackgroundRecent studies have shown that the high salt diet (HSD) is linked to increased dermal pro-inflammatory status and reduced extracellular matrix (ECM) expression in inflamed skin of mice. Decreased ECM content is a known aging phenotype of th
Externí odkaz:
https://doaj.org/article/d60ff1b49d1d4986aa215c499f933fc8
Autor:
Lin Zhao, Yi Sun, Xiaoran Yang, Ling Tian, Lize Li, Fangfang Wang, Xiaoye Niu, Lei Diao, Haiyan Li
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Cardiotoxicity and QT interval prolongation have been a common cause of withdrawal of drugs from the market. FCN-437c is an oral, second-generation, potent, and selective CDK4/6 inhibitor for the treatment of patients with HR+/HER2- metastatic breast
Externí odkaz:
https://doaj.org/article/f2cebee37b224c779304de53b04a4ef2
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Externí odkaz:
https://doaj.org/article/ecc747bc67854535a483e533d4d08865
Autor:
Nour Hisham Al-Ziftawi, Shereen Elazzazy, Mohammed Fasihul Alam, Asrul Shafie, Anas Hamad, Salha Bbujassoum, Mohamed Izham Mohamed Ibrahim
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionPalbociclib and ribociclib are indicated in the first-line treatment of hormonal receptor-positive HER-2 negative (HR+/HER2- negative) advanced breast cancer. Although randomized-controlled trials (RCTs) proved their clinical efficacy, th
Externí odkaz:
https://doaj.org/article/18d8b86038294dddb393c817669b1024
Akademický článek
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Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/48889d017f334e9c8e416ed708a32860
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/cd6bd581b13345e380055c7933ea0867
Autor:
Kamila Kaminska, Nina Akrap, Johan Staaf, Carla L. Alves, Anna Ehinger, Anna Ebbesson, Ingrid Hedenfalk, Lukas Beumers, Srinivas Veerla, Katja Harbst, Sidse Ehmsen, Signe Borgquist, Åke Borg, Alejandro Pérez-Fidalgo, Henrik J. Ditzel, Ana Bosch, Gabriella Honeth
Publikováno v:
Breast Cancer Research, Vol 23, Iss 1, Pp 1-18 (2021)
Abstract Background Resistance to endocrine treatment in metastatic breast cancer is a major clinical challenge. Clinical tools to predict both drug resistance and possible treatment combination approaches to overcome it are lacking. This unmet need
Externí odkaz:
https://doaj.org/article/7cbcb174cf144b08807aab383e525e6b
Autor:
Alexandre Bergeron, Vanessa Hertig, Louis Villeneuve, Vincent Chauvette, Ismail El‐Hamamsy, Angelino Calderone
Publikováno v:
Physiological Reports, Vol 10, Iss 8, Pp n/a-n/a (2022)
Abstract Male sex and hypertension represent risk factors in the progression of an aortic aneurysm. The present study examined the morphological/cellular phenotype of the ascending aorta (AA) of male and female patients diagnosed with a bicuspid aort
Externí odkaz:
https://doaj.org/article/ac2483885a0c4829a1e457446ba9afb5