Zobrazeno 1 - 10
of 1 570
pro vyhledávání: '"Cell therapies"'
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-30 (2024)
Abstract Adoptive T cell therapy is a pivotal strategy in cancer immunotherapy, demonstrating potent clinical efficacy. However, its limited durability often results in primary resistance. High-throughput screening technologies, which include both ge
Externí odkaz:
https://doaj.org/article/bedbc000af50411f9315fd5d66600049
Publikováno v:
Translational Neurodegeneration, Vol 13, Iss 1, Pp 1-19 (2024)
Abstract Background Tumorigenicity represents a critical challenge in stem cell-based therapies requiring rigorous monitoring. Conventional approaches for tumorigenicity evaluation are based on animal models and have numerous limitations. Brain organ
Externí odkaz:
https://doaj.org/article/c0a457e8605d4fd786ff0d529ed4176f
Autor:
Emma M. McErlean, Helen O. McCarthy
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-28 (2024)
Abstract Natural Killer (NK) cells are exciting candidates for cancer immunotherapy with potent innate cytotoxicity and distinct advantages over T cells for Chimeric Antigen Receptor (CAR) therapy. Concerns regarding the safety, cost, and scalability
Externí odkaz:
https://doaj.org/article/b2e42061d55e4d1e9ba4d72fcbae4d03
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-23 (2024)
Abstract Adoptive cell therapies (ACTs) have revolutionized cancer immunotherapy, prompting exploration into their application against oncoviruses. Oncoviruses such as human papillomavirus (HPV), hepatitis B virus (HBV), hepatitis C virus (HCV), and
Externí odkaz:
https://doaj.org/article/d121212ab19b4671babb5334ebe54495
Publikováno v:
Immuno-Oncology and Technology, Vol 24, Iss , Pp 100715- (2024)
Adoptive T-cell therapies (ACTs) including tumor-infiltrating lymphocytes and engineered T cells (transgenic T-cell receptor and chimeric antigen receptor T cells), have made an important impact in the field of cancer treatment over the past years. M
Externí odkaz:
https://doaj.org/article/6ef38b9b6f22495caca2bd7c8d2a65f8
Autor:
F. Salamanna, D. Contartese, G. Tedesco, A. Ruffilli, M. Manzetti, G. Viroli, M. Traversari, C. Faldini, G. Giavaresi
Publikováno v:
JOR Spine, Vol 7, Iss 3, Pp n/a-n/a (2024)
Abstract Over the past several decades, there has been a notable increase in the total number of spinal fusion procedures worldwide. Advanced spinal fusion techniques, surgical approaches, and new alternatives in grafting materials and implants, as w
Externí odkaz:
https://doaj.org/article/5503e6f93e0845329d978d418db59cad
Publikováno v:
BMC Veterinary Research, Vol 20, Iss 1, Pp 1-10 (2024)
Abstract Background Multiple sclerosis (MS) is a chronic condition that primarily manifests as demyelination of neuronal axons in the central nervous system, due to the loss or attack of oligodendroglia cells that form myelin. Stem cell therapy has s
Externí odkaz:
https://doaj.org/article/f06a78bd6c7c4beba6a78d6a29ecae3c
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-5 (2024)
Abstract The clinical application of cell therapies is becoming increasingly important for the treatment of cancer, congenital immune deficiencies, and hemoglobinopathies. These therapies have been primarily manufactured and used at academic medical
Externí odkaz:
https://doaj.org/article/0510a849cc8a462f9c68ad81b9daac86
Autor:
Gustavo Balbinot
Publikováno v:
Frontiers in Rehabilitation Sciences, Vol 4 (2024)
Spinal cord injury (SCI) is a profoundly debilitating condition with no effective treatment to date. The complex response of the central nervous system (CNS) to injury and its limited regeneration capacity pose bold challenges for restoring function.
Externí odkaz:
https://doaj.org/article/33adc9cccc8b436fb33ec6ca43117110
Autor:
Avijeet Kumar Mishra, Waseem Qasim
Publikováno v:
EJC Paediatric Oncology, Vol 3, Iss , Pp 100149- (2024)
Autologous chimeric antigen receptor (CAR) T cell therapy has revolutionised the management of certain B-cell malignancies. However, as bespoke therapies, challenges include complex manufacturing logistics and risks ranging from suboptimal harvests t
Externí odkaz:
https://doaj.org/article/3b24bea66be0487b94d4b6371d83a5c1