Zobrazeno 1 - 10
of 344
pro vyhledávání: '"Cell stemness"'
Publikováno v:
Shanghai Jiaotong Daxue xuebao. Yixue ban, Vol 44, Iss 11, Pp 1370-1382 (2024)
Objective·To identify the functional motifs of mucin 1 (MUC1) involved in regulating tumor cell proliferation, migration, and stemness maintenance.Methods·Mutational characteristics of the MUC1 gene across different cancers were identified from The
Externí odkaz:
https://doaj.org/article/18870c6f69344488a938d05d036fa083
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Background Gastrointestinal mesenchymal stromal tumors (GISTs) are a group of intramural tumors that exhibit a wide range of morphologies. Dysfunction or loss of interstitial cells of Cajal (ICCs) is correlated with the disorders of gastroin
Externí odkaz:
https://doaj.org/article/456fab38cedd4e888b6dedac01875e93
Publikováno v:
Translational Oncology, Vol 51, Iss , Pp 102155- (2025)
The incidence of prostate cancer (PCa) is increasing annually, making it the leading cause of tumor-related mortality in males. The available treatment options for metastatic PCa are limited. Vasculogenic mimicry (VM), an emerging phenomenon involvin
Externí odkaz:
https://doaj.org/article/56cb46699ea84fb18ea4062a03482659
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
BackgroundCancer stem cells are characterized by self-renewal, clonal tumor initiation capacity, and treatment resistance, which play essential roles in the tumor progression of prostate cancer (PCa). In this study, we aim to explore the features of
Externí odkaz:
https://doaj.org/article/23ae8ab18d3a42259239f85c1e197186
Publikováno v:
Annals of Medicine, Vol 56, Iss 1 (2024)
AbstractBackground The chemotherapy resistance often leads to chemotherapy failure. This study aims to explore the molecular mechanism by which MUC1 regulates paclitaxel resistance in lung adenocarcinoma (LUAD), providing scientific basis for future
Externí odkaz:
https://doaj.org/article/ce78e1fb238942bca79b5cded5cf5199
Autor:
Liu, Bide a, b, Li, Xun a, b, Wang, Shuheng a, b, Jia, Hongliang a, b, Zhang, Xiaoan a, b, Dong, Qiang a, b, Li, Jiuzhi a, b, ⁎
Publikováno v:
In Translational Oncology January 2025 51
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract Background Tumor cells with stemness in breast cancer might facilitate the immune microenvironment’s suppression process and led to anti-tumor immune effects. The primary objective of this study was to identify potential targets to disrupt
Externí odkaz:
https://doaj.org/article/b27bdccfb92a4cada7516d078a8e90bb
Publikováno v:
The Clinical Respiratory Journal, Vol 17, Iss 9, Pp 884-892 (2023)
Abstract Background Cancer stem cells are pivotal in cancer progression and therapy, including lung adenocarcinoma (LUAD). High NCAPG level is implicated in malignant tumorigenesis, but investigations on NCAPG and LUAD stem cells are warranted. Hence
Externí odkaz:
https://doaj.org/article/a5cae6a06527482c9016235621f70b26
Autor:
Yuan Gao, Miao Yu, Zengyuan Liu, Yi Liu, Zhijun Kong, Chunfu Zhu, Xihu Qin, Yan Li, Liming Tang
Publikováno v:
Translational Oncology, Vol 41, Iss , Pp 101858- (2024)
ALKBH5 plays critical roles in various cellular processes via post-transcriptional regulation of oncogenes or tumor suppressors in an N6-methyladenosine (m6A)-dependent manner. However, its function in intrahepatic cholangiocarcinoma (ICC) remains un
Externí odkaz:
https://doaj.org/article/57566b3a422e42958cf438ddfd79c95c
Autor:
Jin Chen, Zhongqiu Wu, Wenyi Deng, Minying Tang, Lvying Wu, Na Lin, Liuyan Chen, Yunfeng Fu, Min Zhao, Changguo Chen, Wenting Li
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Background USP51 is a deubiquitinase (DUB), that is involved in diverse cellular processes. Accumulating evidence has demonstrated that USP51 contributes to cancer development. However, its impact on non-small cell lung carcinoma (NSCLC) cel
Externí odkaz:
https://doaj.org/article/63db764755e24887a0ee35e138a1959f