Zobrazeno 1 - 10
of 485
pro vyhledávání: '"Cell resistance"'
Publikováno v:
Heliyon, Vol 10, Iss 16, Pp e36057- (2024)
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), also known as APO2L, has emerged as a highly potential anticancer agent because of its capacity to effectively trigger apoptosis in tumor cells by specifically binding to either of its
Externí odkaz:
https://doaj.org/article/b9a85ac54ef14060bb088af77a45e577
Autor:
Chou-Yi Hsu, Ahmed Mahdi Rheima, Mustafa M. Kadhim, Nada Nadhim Ahmed, Srwa Hashim Mohammed, Fatima Hashim Abbas, Zainab Talib Abed, Zahra Muhammed Mahdi, Zainab Sabri Abbas, Safa K. Hachim, Farah K. Ali, Zaid H Mahmoud, Ehsan Kianfar
Publikováno v:
South African Journal of Chemical Engineering, Vol 46, Iss , Pp 233-270 (2023)
Today, in diverse medical and clinical fields, including cancer treatment, nanoscience has evolved and evolved. Cancer and its forms, on the other hand, have been rumored and inclusive, and many individuals suffer from this fatal and lethal condition
Externí odkaz:
https://doaj.org/article/75831aa091ed4551a273c6e1a10b73be
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 6260 (2024)
Canonical transient receptor potential channel 3 (TRPC3) is the most abundant TRPC channel in the brain and is highly expressed in all subfields of the hippocampus. Previous studies have suggested that TRPC3 channels may be involved in the hyperexcit
Externí odkaz:
https://doaj.org/article/b35f9c9b3ee1483ba914fdbc9dde0204
Publikováno v:
Machinery & Energetics, Vol 13, Iss 4, Pp 60-71 (2022)
The change in the impedance of biological tissue under the influence of voltage is used in the diagnosis and treatment of various diseases. Mathematical models describing physical and biological processes in biological objects are based on electrical
Externí odkaz:
https://doaj.org/article/e6669d5418804b9a80f0286c2fa52979
Akademický článek
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Autor:
Yuan-Na Lin, Marcel O. Schmidt, Ghada M. Sharif, Eveline E. Vietsch, Amber J. Kiliti, Megan E. Barefoot, Anna T. Riegel, Anton Wellstein
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
Pancreatic cancer remains largely unresponsive to immune modulatory therapy attributable in part to an immunosuppressive, desmoplastic tumor microenvironment. Here, we analyze mechanisms of cancer cell-autonomous resistance to T cells. We used a 3D c
Externí odkaz:
https://doaj.org/article/2d24f4c980be417c897fa5b984546e5d
Akademický článek
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Autor:
Nicole Cordes, Carolin Kolbe, Dominik Lock, Tatjana Holzer, Deborah Althoff, Daniel Schäfer, Franziska Blaeschke, Bettina Kotter, Sandra Karitzky, Claudia Rossig, Toni Cathomen, Tobias Feuchtinger, Iris Bürger, Mario Assenmacher, Thomas Schaser, Andrew D. Kaiser
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 21, Iss , Pp 42-53 (2021)
Recently, a rare type of relapse was reported upon treating a B cell acute lymphoblastic leukemia (B-ALL) patient with anti-CD19 chimeric antigen receptor (CAR)-T cells caused by unintentional transduction of residual malignant B cells (CAR-B cells).
Externí odkaz:
https://doaj.org/article/c35a2ae8e0aa4f12be416e571f892b51
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6863 (2023)
3-Amino-1,2,4-benzotriazine-1,4-dioxide (tirapazamine, TPZ) and other heteroaromatic N-oxides (ArN→O) exhibit tumoricidal, antibacterial, and antiprotozoal activities. Their action is attributed to the enzymatic single-electron reduction to free ra
Externí odkaz:
https://doaj.org/article/510fbff2fba34a2baedd13e7d78985be
Autor:
Miguel Ponce-de-Leon, Arnau Montagud, Charilaos Akasiadis, Janina Schreiber, Thaleia Ntiniakou, Alfonso Valencia
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
The emergence of cell resistance in cancer treatment is a complex phenomenon that emerges from the interplay of processes that occur at different scales. For instance, molecular mechanisms and population-level dynamics such as competition and cell–
Externí odkaz:
https://doaj.org/article/ad585a2cdd25458f858a866dbad62f6a