Zobrazeno 1 - 10
of 1 923
pro vyhledávání: '"Cell reprogramming"'
Autor:
Yena Nam, Yoonji Song, Seung Ju Seo, Ga Ryang Ko, Seung Hyun Lee, Eunju Cha, Su Min Kwak, Sumin Kim, Mikyung Shin, Yoonhee Jin, Jung Seung Lee
Publikováno v:
MedComm, Vol 5, Iss 12, Pp n/a-n/a (2024)
Abstract Heart degenerative diseases pose a significant challenge due to the limited ability of native heart to restore lost cardiomyocytes. Direct cellular reprogramming technology, particularly the use of small molecules, has emerged as a promising
Externí odkaz:
https://doaj.org/article/9ac65995c9ca41aab2584e07d9a0eb43
Autor:
Gabriela Pavlinkova, Ondrej Smolik
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Transcription factors belonging to the basic helix-loop-helix (bHLH) family are key regulators of cell fate specification and differentiation during development. Their dysregulation is implicated not only in developmental abnormalities but also in va
Externí odkaz:
https://doaj.org/article/71739581bd5c41e0bfdcf6b5939e0738
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 11, Pp 2444-2455 (2024)
Parkinson’s disease is typically characterized by the progressive loss of dopaminergic neurons in the substantia nigra pars compacta. Many studies have been performed based on the supplementation of lost dopaminergic neurons to treat Parkinson’s
Externí odkaz:
https://doaj.org/article/a755e1e9f93c478dafa883a9581024a6
Autor:
Andrey Volnitskiy, Konstantin Shabalin, Rimma Pantina, Elena Varfolomeeva, Roman Kovalev, Vladimir Burdakov, Svetlana Emelianova, Luiza Garaeva, Alexander Yakimov, Marina Sogoyan, Michael Filatov, Andrey L. Konevega, Tatiana Shtam
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 2, Pp 1107-1120 (2024)
The OCT4 transcription factor is necessary to maintain cell stemness in the early stages of embryogenesis and is involved in the formation of induced pluripotent stem cells, but its role in oncogenesis is not yet entirely clear. In this work, OCT4 ex
Externí odkaz:
https://doaj.org/article/240e4b208c2f418dbc1bf9dccd2c40d6
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/8e513794719f4b6bb6a3fbcb017e4975
Autor:
B. Péault
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Externí odkaz:
https://doaj.org/article/8309d7e4dec241bc81493f3585807d1f
Autor:
I. V. Kizub
Publikováno v:
Regulatory Mechanisms in Biosystems, Vol 14, Iss 3, Pp 451-468 (2023)
The discovery of methods for reprogramming adult somatic cells into induced pluripotent stem cells (iPSCs) opens up prospects of developing personalized cell-based therapy options for a variety of human diseases as well as disease modeling and new dr
Externí odkaz:
https://doaj.org/article/5c84f31a00244fbeb4c80336b47d0c52
Publikováno v:
Advances in Ophthalmology Practice and Research, Vol 3, Iss 3, Pp 126-133 (2023)
Background: Retinal diseases characterized with irreversible loss of retinal nerve cells, such as optic atrophy and retinal degeneration, are the main causes of blindness. Current treatments for these diseases are very limited. An emerging treatment
Externí odkaz:
https://doaj.org/article/20649f1f023847e692a1f49d75eff09f
Publikováno v:
Molecular Medicine, Vol 29, Iss 1, Pp 1-10 (2023)
Abstract The telomerase RNA component (TERC) gene plays an important role in telomerase-dependent extension and maintenance of the telomeres. In the event of TERC haploinsufficiency, telomere length is often affected; this, in turn, can result in the
Externí odkaz:
https://doaj.org/article/128b3885f075411c8a3c5042722c26e4
Autor:
Alvin Y. Liu
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Multiple cancer cell types are found in prostate tumors. They are either luminal-like adenocarcinoma or less luminal-like and more stem-like non-adenocarcinoma and small cell carcinoma. These types are lineage related through differentiation. Loss of
Externí odkaz:
https://doaj.org/article/b9f04accbf0f493a9c399268341ae5f4