Zobrazeno 1 - 10
of 1 755
pro vyhledávání: '"Cell phenotype"'
Autor:
Ahmed A. Y. Ragab, Margaret F. Doyle, Jiachen Chen, Yuan Fang, Kathryn L. Lunetta, Joanne M. Murabito
Publikováno v:
Immunity & Ageing, Vol 21, Iss 1, Pp 1-10 (2024)
Abstract Background Global life expectancy is rising, with the 60 + age group projected to hit 2 billion by 2050. Aging impacts the immune system. A notable marker of immune system aging is the presence of Aging-Related Immune Cell Phenotypes (ARIPs)
Externí odkaz:
https://doaj.org/article/c41cb3cf9955436687290af42e544dee
Autor:
Lu Song, He Qiu, Zhiru Chen, Jing Wang, Yang Xu, Zhanhong Liu, Shuo Liu, Zhiyuan Wang, Xiangdong Zhu, Kai Zhang, Hai Lin, Xingdong Zhang
Publikováno v:
Collagen and Leather, Vol 6, Iss 1, Pp 1-16 (2024)
Abstract Collagen, known for its excellent biocompatibility and biological properties, has limited in vivo maintenance duration after implantation, while hyaluronic acid faces challenges such as various complications and insufficient support for cell
Externí odkaz:
https://doaj.org/article/8a61a867c75841bb8e3d3a5cb9129612
Autor:
Guangqi Li, Qinhui Li, Yongqing Tong, Jin Zeng, Tiantian Dang, Ningai Yang, Yuning Zhou, Lei Ma, Qirui Ge, Zhijun Zhao
Publikováno v:
Cancer Biology & Therapy, Vol 25, Iss 1 (2024)
Lung adenocarcinoma is the most prevalent subtype of lung cancer, which is the leading cause of cancer-related mortality worldwide. Toxoplasma gondii (T.gondii) Rhoptry protein 16 (ROP16) has been shown to quickly enter the nucleus, and through activ
Externí odkaz:
https://doaj.org/article/276cd395658c4f2397ffc1a5c9a42d39
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/ae56a40c2b6b4feb8483cb98c5bf0259
Autor:
Chun-yan Zuo, Zhengwei Hu, Xiao-yan Hao, Meng-jie Li, Jing-jing Shi, Meng-nan Guo, Dong-rui Ma, Shuang-jie Li, Yuan-yuan Liang, Chan Zhang, Cheng-yuan Mao, Yuming Xu, Chang-he Shi
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
IntroductionAlzheimer’s disease (AD) is the most widespread neurodegenerative disease in the world. Previous studies have shown that peripheral immune dysregulation plays a paramount role in AD, but whether there is a protective causal relationship
Externí odkaz:
https://doaj.org/article/0871f6887b114830bfddf21233ed817a
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Background:Osteomyelitis is a severe bone marrow infection, whose pathogenesis is not yet fully understood. This study aims to explore the causal relationship between immune cell characteristics and osteomyelitis, hoping to provide new insights for t
Externí odkaz:
https://doaj.org/article/13b83d8b6c404a5ca23498e250f3ab9d
Autor:
Qi-Xin Shang, Yu-Shang Yang, Han-Lu Zhang, Ya-Ping Cheng, Han Lu, Yong Yuan, Long-Qi Chen, Ai-Fang Ji
Publikováno v:
Heliyon, Vol 10, Iss 1, Pp e23832- (2024)
Background: Esophageal squamous cell carcinoma (ESCC) is a common pathological esophageal cancer with poor prognosis. Vitamin D deficiency reportedly occurs in ESCC patients, and this is related to single nucleotide polymorphism of vitamin D receptor
Externí odkaz:
https://doaj.org/article/1687ea1bd9c7402b9daf72444260aa78
Autor:
Xudong Xing, Mengru Sun, Zifan Guo, Yongjuan Zhao, Yuru Cai, Ping Zhou, Huiying Wang, Wen Gao, Ping Li, Hua Yang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 9, Pp 3802-3816 (2023)
The chemical complexity of traditional Chinese medicines (TCMs) makes the active and functional annotation of natural compounds challenging. Herein, we developed the TCMs-Compounds Functional Annotation platform (TCMs-CFA) for large-scale predicting
Externí odkaz:
https://doaj.org/article/cfcfe7cf5bdf4b0c8023bb63b4383d37
Autor:
Elena Tassi, Alice Bergamini, Jessica Wignall, Miriam Sant’Angelo, Emanuela Brunetto, Chiara Balestrieri, Miriam Redegalli, Alessia Potenza, Danilo Abbati, Francesco Manfredi, Maria Giulia Cangi, Gilda Magliacane, Fabiola Scalisi, Eliana Ruggiero, Maria Chiara Maffia, Federica Trippitelli, Emanuela Rabaiotti, Raffaella Cioffi, Luca Bocciolone, Giorgio Candotti, Massimo Candiani, Gianluca Taccagni, Birgit Schultes, Claudio Doglioni, Giorgia Mangili, Chiara Bonini
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionDespite predicted efficacy, immunotherapy in epithelial ovarian cancer (EOC) has limited clinical benefit and the prognosis of patients remains poor. There is thus a strong need for better identifying local immune dynamics and immune-supp
Externí odkaz:
https://doaj.org/article/922dcb22f26e463191e455023be98e2a
Autor:
María Rodríguez-López, Nicola Bordin, Jon Lees, Harry Scholes, Shaimaa Hassan, Quentin Saintain, Stephan Kamrad, Christine Orengo, Jürg Bähler
Publikováno v:
eLife, Vol 12 (2023)
Many proteins remain poorly characterized even in well-studied organisms, presenting a bottleneck for research. We applied phenomics and machine-learning approaches with Schizosaccharomyces pombe for broad cues on protein functions. We assayed colony
Externí odkaz:
https://doaj.org/article/1e2e0ac5bcd64e5a95d52821d8b5c76a