Zobrazeno 1 - 10
of 1 158
pro vyhledávání: '"Cell models"'
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Obesity is a serious global illness that is frequently associated with metabolic syndrome. Adipocytes are the typical cells of adipose organ, which is composed of at least two different tissues, white and brown adipose tissue. They functiona
Externí odkaz:
https://doaj.org/article/f210d4ad1f8f499696313cd75423ee4b
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-20 (2024)
Abstract To protect against the constant threat of inhaled pathogens, the lung is equipped with cellular defenders. In coordination with resident and recruited immune cells, this defence is initiated by the airway and alveolar epithelium following th
Externí odkaz:
https://doaj.org/article/22082f76e19c436ab07516d01e31451b
Publikováno v:
Shipin Kexue, Vol 45, Iss 5, Pp 303-313 (2024)
Anthocyanins are ubiquitous in plants, and many studies indicate that they possess diverse biological activities depending on their bioaccessibility and bioavailability. Numerous studies have revealed that absorption and transport by intestinal epith
Externí odkaz:
https://doaj.org/article/6282fdf23ecf4590b0b30e5603fed179
Autor:
Zhoujiang Chen, Ji Wang, Ranjith Kumar Kankala, Mingli Jiang, Lianlin Long, Wei Li, Liang Zou, Aizheng Chen, Ya Liu
Publikováno v:
Materials Today Bio, Vol 29, Iss , Pp 101280- (2024)
In vitro drug screening endeavors to replicate cellular states closely resembling those encountered in vivo, thereby maximizing the fidelity of drug effects and responses within the body. Decellularized extracellular matrix (dECM)-based materials off
Externí odkaz:
https://doaj.org/article/a409d9bc323a45c48f1e8e44e9491f0e
Autor:
Chrysanthi‐Maria Moysidou, Douglas C. van Niekerk, Verena Stoeger, Charalampos Pitsalidis, Lorraine A. Draper, Aimee M. Withers, Katherine Hughes, Reece McCoy, Rachana Acharya, Colin Hill, Róisín M. Owens
Publikováno v:
Small Science, Vol 4, Iss 6, Pp n/a-n/a (2024)
The role of the gut microbiome in various aspects of health and disease is now a well‐established concept in modern biomedicine. Numerous studies have revealed links between host health and microbial activity, spanning from digestion and metabolism
Externí odkaz:
https://doaj.org/article/db790b9dad6349f7bb6ccb31668617ec
Publikováno v:
Biomedicines, Vol 12, Iss 10, p 2262 (2024)
Pluripotent stem cells (PSCs) offer many potential research and clinical benefits due to their ability to differentiate into nearly every cell type in the body. They are often used as model systems to study early stages of ontogenesis to better under
Externí odkaz:
https://doaj.org/article/5605845acd3346518c7863f325b34705
Autor:
Alessio Romaldini, Raffaele Spanò, Marina Veronesi, Benedetto Grimaldi, Tiziano Bandiera, Stefania Sabella
Publikováno v:
Cells, Vol 13, Iss 18, p 1542 (2024)
Three-dimensional hepatic cell cultures can provide an important advancement in the toxicity assessment of nanomaterials with respect to 2D models. Here, we describe liver organoids (LOs) obtained by assembling multiple cell lineages in a fixed ratio
Externí odkaz:
https://doaj.org/article/4fbaf6085cd347358c97a8d36668d571
Autor:
Luis M. Ortiz Jordan, Virneliz Fernández Vega, Justin Shumate, Adam Peles, Jordan Zeiger, Louis Scampavia, Timothy P. Spicer
Publikováno v:
SLAS Discovery, Vol 29, Iss 3, Pp 100141- (2024)
High Throughput Screening (HTS) with 3D cell models is possible thanks to the recent progress and development in 3D cell culture technologies. Results from multiple studies have demonstrated different drug responses between 2D and 3D cell culture. It
Externí odkaz:
https://doaj.org/article/482d07966d634fcfad48ee4a6637718a
Autor:
E. V. Petersen, D. A. Chudakova, D. B. Erdyneeva, A. A. Kalinkin, R. Claros, E. Y. Shabalina, D. A. Gudkov, О. A. Mynbaev, I. V. Reshetov
Publikováno v:
Сибирский онкологический журнал, Vol 22, Iss 3, Pp 108-118 (2023)
The purpose of the study was to summarize and analyze modern data about non-invasive methods of molecular diagnosis and approaches to the personalized therapy of diffuse midline glioma (DMG). Material and Methods. The search and analysis of publicati
Externí odkaz:
https://doaj.org/article/81b95bb6b17c46429bca0cceda628f43
Autor:
I. A. Mazerkina
Publikováno v:
Безопасность и риск фармакотерапии, Vol 11, Iss 2, Pp 131-144 (2023)
Drug-induced liver injury (DILI) is the reason for 15–18% of medicinal product recalls from the market. Since interspecies differences often limit the relevance of standard non-clinical tests in vivo, a promising alternative is to develop cell-base
Externí odkaz:
https://doaj.org/article/ac9a3258dd264805a6b94a306344ff27